IHEM 20887
INSTITUTO DE HISTOLOGIA Y EMBRIOLOGIA DE MENDOZA DR. MARIO H. BURGOS
Unidad Ejecutora - UE
capítulos de libros
Título:
Virus maturation
Autor/es:
LAURA RUTH DELGUI; JOSÉ F. RODRÍGUEZ
Libro:
Structure and Physics of Viruses
Editorial:
Springer
Referencias:
Lugar: Heidelberg; Año: 2013; p. 395 - 415
Resumen:
The formation of infectious virus particles is a highly complex process involving a series of sophisticated molecular events. In most cases, the assembly of virus structural elements results in the formation of immature virus particles unable to initiate a productive infection. Accordingly, for most viruses the final stage of the assembly pathway entails a set of structural transitions and/or biochemical modifications that transform inert precursor particles into fully infectious agents. In this chapter, we review the most relevant maturation mechanisms involved in the generation of infectious virions for a wide variety of viruses.
