IHEM 20887
INSTITUTO DE HISTOLOGIA Y EMBRIOLOGIA DE MENDOZA DR. MARIO H. BURGOS
Unidad Ejecutora - UE
artículos
Título:
Coxiella burnetii: living inside the host cell
Autor/es:
BERÓN W; DISTEL JS; ORTIZ FLORES, RM
Revista:
BIOCELL
Editorial:
Tech Science Press
Referencias:
Lugar: Mendoza; Año: 2019 vol. 43 p. 1 - 6
ISSN:
0327-9545
Resumen:
Coxiella burnetii is an obligate intracellular pathogen and the causative agent of Q fever. In this brief review, we describe how recently described mechanisms help our understanding of C. burnetii invasion and its survival in the host cell by the formation of a replicative niche: the Coxiella-containing vacuole. We describe the actin-associated proteins involved in the internalization of C. burnetii, and we discuss the contribution of diverse degradation pathways of the cell during the formation and stabilization of the Coxiella-containing vacuole.
