IHEM 20887
INSTITUTO DE HISTOLOGIA Y EMBRIOLOGIA DE MENDOZA DR. MARIO H. BURGOS
Unidad Ejecutora - UE
artículos
Título:
PAX6 Promoter Methylation Correlates with MDA-MB-231 Cell Migration, and Expression of MMP2 and MMP9
Autor/es:
CAMPOY, EMANUEL; URRUTIA, GUILLERMO; ROQUÉ, MARÍA; DANIELA L. NASIF; CAMPOY, EMANUEL; URRUTIA, GUILLERMO; ROQUÉ, MARÍA; DANIELA L. NASIF; SERGIO LAURITO; BRANHAM, MARÍA T.; SERGIO LAURITO; BRANHAM, MARÍA T.
Revista:
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION
Editorial:
ASIAN PACIFIC ORGANIZATION CANCER PREVENTION
Referencias:
Año: 2018 vol. 19
ISSN:
1513-7368
Resumen:
Breast cancer is a heterogeneous disease characterized by an accumulation of genetic and epigenetic alterations that lead tumor cells to acquire characteristics like the capacity for invasion and metastasis. Metastasis remains a major challenge in cancer management and understanding of its molecular basis should result in improved prevention, diagnosis, and treatment of breast cancer patients. The aim of this study was to investigate how promoter DNA methylation regulates PAX6 gene expression and influences breast carcinoma cell migration.
