IHEM   20887
INSTITUTO DE HISTOLOGIA Y EMBRIOLOGIA DE MENDOZA DR. MARIO H. BURGOS
Unidad Ejecutora - UE
artículos
Título:
Small RAB GTPases Regulate Multiple Steps of Mitosis
Autor/es:
MISEREY-LENKEI, STÉPHANIE; COLOMBO, MARÍA I.
Revista:
Frontiers in Cell and Developmental Biology
Editorial:
Frontiers
Referencias:
Año: 2016 vol. 4
Resumen:
GTPases of the RAB family are key regulators of multiple steps of membrane trafficking. Several members of the RAB GTPase family have been implicated in mitotic progression. In this review, we will first focus on the function of endosome-associated RAB GTPases reported in early steps of mitosis, spindle pole maturation, and during cytokinesis. Second, we will discuss the role of Golgi-associated RAB GTPases at the metaphase/anaphase transition and during cytokinesis.