LANDA, MARIA SILVINA; SCHUMAN, MARIANO LUIS; AISICOVICH, MAIA; PERES DIAZ, LUDMILA S; GIRONACCI, MARIELA; GARCÍA, SILVIA INÉS; PIROLA, CARLOS JOSE

Valproate Decreases Transgenerationally Blood Pressure by Affecting Thyrotropin-releasing Hormone Promoter DNA Methylation and Gene Expression in Spontaneously Hypertensive Rat

MOLECULAR AND CELLULAR BIOCHEMISTRY; Año: 2024

PERES DIAZ, LUDMILA SOLEDAD; AISICOVICH, MAIA; SCHUMAN, MARIANO LUIS; ROSATI MACARENA; TOBLLI, JORGE EDUARDO; ANA UCEDA; GRACIELA GIARDINA; LANDA, MARIA SILVINA; GARCÍA, SILVIA INÉS

Novel leptin-cardiacTRH pathway responsible of the cardiac alterations in the hyperleptinemic obesity

MOLECULAR AND CELLULAR BIOCHEMISTRY; Lugar: Berlin; Año: 2024

VALLI, EDUARDO; DALOTTO?MORENO, TOMÁS; STERLE, HELENA A.; MÉNDEZ?HUERGO, SANTIAGO P.; PAULAZO, MARÍA A.; GARCÍA, SILVIA I.; PIROLA, CARLOS J.; KLECHA, ALICIA J.; RABINOVICH, GABRIEL A.; CREMASCHI, GRACIELA A.

Hypothyroidism‐associated immunosuppression involves induction of galectin‐1‐producing regulatory T cells

FASEB JOURNAL; Año: 2023 vol. 37

SCHUMAN, MARIANO LUIS; PERES DIAZ, LUDMILA S; AISICOVICH, MAIA; INGALLINA FERNANDO; TOBLLI, J; LANDA, MARIA SILVINA; GARCIA , SILVIA INES

Cardiac thyrotropin-releasing hormone (TRH) inhibition improves ventricular function and reduces hypertrophy and fibrosis after myocardial infarction in rats.

JOURNAL OF CARDIAC FAILURE; Año: 2021

LANDA, MARÍA SILVINA; GARCÍA, SILVIA INÉS; SCHUMAN, MARIANO LUIS; PERES DIAZ, LUDMILA SOLEDAD; AISICOVICH, MAIA; PIROLA, CARLOS JOSÉ

Cardiovascular and body weight regulation changes in transgenic mice overexpressing thyrotropin-releasing hormone (TRH)

JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY; Lugar: Navarra; Año: 2020

PERES DIAZ, LUDMILA SOLEDAD; SCHUMAN, MARIANO LUIS; AISICOVICH, MAIA; TOBLLI, JORGE EDUARDO; PIROLA, CARLOS JOSÉ; LANDA, MARÍA SILVINA; GARCÍA, SILVIA INÉS

Short-term doxorubicin cardiotoxic effects: involvement of cardiac Thyrotropin Releasing Hormone system

LIFE SCIENCES; Año: 2020 vol. 261

PERES DIAZ, LUDMILA S; SCHUMAN, MARIANO LUIS; AISICOVICH MAIA; TOBLLI, J; PIROLA, CARLOS JOSE; LANDA, MARIA SILVINA; GARCIA , SILVIA INES

Angiotensin II Requires an Intact Cardiac Thyrotropin-Releasing Hormone (TRH) System to Induce Cardiac Hypertrophy in Mouse.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY; Lugar: Amsterdam; Año: 2018 vol. 114 p. 1 - 11

SCHUMAN, MARIANO LUIS; PERES DIAZ LUDMILA; LANDA, MARIA SILVINA; TOBLLI, J; CAO, GABRIEL; ALVAREZ, AZUCENA LAURA; FINKIELMAN, SAMUEL; PIROLA, CARLOS JOSE; GARCIA , SILVIA INES

Thyrotropin-releasing hormone overexpression induces structural changes

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY; Lugar: Philadelphia; Año: 2014

LANDA, MARIA SILVINA; SCHUMAN, MARIANO LUIS; PERES DIAZ LUDMILA; GARCIA , SILVIA INES; PIROLA, CARLOS JOSE

THYROTROPIN-RELEASING HORMONE (TRH) MAY MEDIATE SYMPATHETIC ACTION AND ARTERIAL BLOOD PRESSURE INCREASE IN OFFSPRING OF MATERNAL OBESITY. In: Hypertension. eLetters [Internet]. Dallas

HYPERTENSION; Lugar: Philadelphia; Año: 2014 p. 1 - 2

LOPEZ VERILLI, M; RODRIGUEZ FERMEPIN, M ; LONGO CARBAJOSA, N; LANDA, MARIA SILVINA; CERRATO, B; GARCÍA SILVIA INES; FERNANDEZ, B; GIRONACCI, MM

Angiotensin 1-7 through MAS receptor upregulates neuronal norepinephrine transporter via AKT and ERK 1/2 dependent pathways

JOURNAL OF NEUROCHEMISTRY; Año: 2012 vol. 120 p. 46 - 55

SCHUMAN, MARIANO LUIS; LANDA, MARIA SILVINA; TOBLLI, J; PERES DIAZ, LUDMILA S; ALVAREZ, AZUCENA LAURA; FINKIELMAN, SAMUEL; PAZ, LEONARDO; CAO, GABRIEL; PIROLA, CARLOS JOSE; GARCIA , SILVIA INES

Cardiac Thyrotropin Releasing Hormone (TRH) mediates left ventricular hypertrophy in Spontaneously Hypertensive Rats (SHR)

HYPERTENSION; Año: 2011 vol. 57 p. 103 - 109

GEMMA, CAROLINA; SOOKOIAN SILVIA,; DIEUZEIDE, G; GARCIA , SILVIA INES; FERNANDEZ GIANOTTI, T; GONZALEZ, C; PIROLA, CARLOS JOSE

Methylation of TFAM gene promoter in peripheral white blood cells is associated with insulin resistance in adolescents

MOLECULAR GENETICS AND METABOLISM; Año: 2010

LANDA, MARIA SILVINA; GARCIA , SILVIA INES; PIROLA, CARLOS JOSE

"Protein tyrosine phosphatase 1B, a major regulator of leptin-mediated control of cardiovascular function"

CIRCULATION RESEARCH; Año: 2010 p. 419 - 419

GEMMA, CAROLINA; SOOKOIAN SILVIA,; J, ALVARIÑAS; GARCIA , SILVIA INES; L, QUINTANA; D, KANEVSKY; GONZALEZ, C; PIROLA, CARLOS JOSE

Maternal Pregestational BMI Is Associated With Methylation of the PPARGC1A Promoter in Newborns.

OBESITY RESEARCH; Año: 2009 vol. 17 p. 1032 - 1039

LANDA, MARIA SILVINA; GARCIA , SILVIA INES; SCHUMAN, MARIANO LUIS; ALVAREZ, AZUCENA LAURA; FINKIELMAN, SAMUEL; PIROLA, CARLOS JOSE

THYROTROPIN-RELEASING HORMONE (TRH) PRECURSOR GENE KNOCKING DOWN IMPEDES MELANOCORTIN-INDUCED HYPERTENSION IN RATS.

HYPERTENSION; Año: 2008

FERNANDEZ GIANOTTI, T; SOOKOIAN SILVIA,; DIEUZEIDE, G; GARCIA , SILVIA INES; GEMMA, CAROLINA; GONZALEZ, C; PIROLA, CARLOS JOSE

A decreased mitochondrial DNA content is related to insulin resistance in adolescents

OBESITY RESEARCH; Año: 2008

LANDA, MARIA SILVINA; GARCIA , SILVIA INES; SCHUMAN, MARIANO LUIS; BURGUEÑO, ADRIANA; ALVAREZ, AZUCENA LAURA; FLAVIA E, SARAVIA; GEMMA, CAROLINA; PIROLA, CARLOS JOSE

KNOCKING DOWN OF THE DIENCEPHALIC THYROTROPIN-RELEASING HORMONE PRECURSOR GENE NORMALIZES OBESITY-INDUCED HYPERTENSION IN THE RAT.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM; Año: 2007 vol. 292 p. 1388 - 1394

BURGUEÑO, ADRIANA LAURA; LANDA, MARIA SILVINA; SCHUMAN, MARIANO LUIS; ALVAREZ, AZUCENA LAURA; JULIETA CARABELLI; GARCIA , SILVIA INES; PIROLA, CARLOS JOSE

Association between diencephalic thyroliberin and arterial blood pressure in agouti-yellow and ob/ob mice may be mediated by leptin.

METABOLISM-CLINICAL AND EXPERIMENTAL; Año: 2007 vol. 56 p. 1439 - 1443

SOOKOIAN SILVIA,; GEMMA, CAROLINA; GARCIA , SILVIA INES; FERNANDEZ GIANOTTI, T; DIEUZEIDE, G; ROUSSOS, A; TONIETTI, M; TRIFONE, L; D, KANEVSKY; GONZALEZ, C; PIROLA, CARLOS JOSE

Short allele of serotonin transporter gene promoter is a risk factor for obesity in adolescents

OBESITY RESEARCH; Año: 2007 vol. 15 p. 271 - 276

LANDA, MARIA SILVINA; SCHUMAN, MARIANO LUIS; BURGUEÑO, ADRIANA LAURA; ALVAREZ, AZUCENA LAURA; GARCIA , SILVIA INES; PIROLA, CARLOS JOSE

SiRNA-mediated silencing of the diencephalic thyrotropin-releasing hormone precursor gene decreases the arterial blood pressure in the obese agouti mice.PMID: 17485311 [PubMed - in process]

Frontiers In Bioscience; Año: 2007 vol. 1 p. 3431 - 3435

KLECHA, AJ; GENARO, AM; GORELIK, G; BARREIRO ARCOS, ML; MAGALI SILBERMAN, D; SCHUMAN, MARIANO LUIS; GARCIA , SILVIA INES; PIROLA, CARLOS JOSE; CREMASCHI, GA

Integrative study of hypothalamus-pituitary-thyroid-immune system interaction: thyroid hormone-mediated modulation of lymphocyte activity through the protein kinase C signaling pathway.

JOURNAL OF ENDOCRINOLOGY; Año: 2006 vol. 189 p. 45 - 55

GEMMA, CAROLINA; SOOKOIAN SILVIA,; J, ALVARIÑAS; GARCIA , SILVIA INES; L, QUINTANA; D, KANEVSKY; C, GONZALEZ; PIROLA, CARLOS JOSE

Mitochondrial DNA depletion in small- and large-for-gestational-age newborns

OBESITY RESEARCH; Año: 2006 vol. 14 p. 2193 - 2199

SOOKOIAN SILVIA,; GARCIA , SILVIA INES; FERNANDEZ GIANOTTI, T; DIEUZEIDE, G; GONZALEZ, C; PIROLA, CARLOS JOSE

The G-308A promoter variant of the tumor necrosis factor-alpha gene is associated with hypertension in adolescents harboring the metabolic syndrome.

AMERICAN JOURNAL OF HYPERTENSION; Año: 2005 vol. 18 p. 1271 - 1275

LANDA, MARIA SILVINA; GARCIA , SILVIA INES; LIBERJEN, LEONARDO; SCHUMAN, MARIANO LUIS; FINKIELMAN, SAMUEL; PIROLA, CARLOS JOSE

Parathyroid hormone-related protein overexpression decreases blood pressure in spontaneously hypertensive rats.

CLINICAL AND EXPERIMENTAL HYPERTENSION; Año: 2005 vol. 27 p. 343 - 354

GARCIA , SILVIA INES; PIROLA, CARLOS JOSE

Thyrotropin-releasing hormone in cardiovascular pathophysiology.

REGULATORY PEPTIDES; Año: 2005 vol. 30 p. 239 - 246

SOOKOIAN SILVIA,; GARCIA , SILVIA INES; CASTAÑO, GUSTAVO; VIUDEZ, P; GONZALEZ, C; PIROLA, CARLOS JOSE

A1166C angiotensin II type 1 receptor gene polymorphism may predict hemodynamic response to losartan in patients with cirrhosis and portal hypertension.

AMERICAN JOURNAL OF GASTROENTEROLOGY; Año: 2005 vol. 100 p. 636 - 642

SOOKOIAN SILVIA,; GARCIA , SILVIA INES; FERNANDEZ GIANOTTI, T; DIEUZEIDE, G; GONZALEZ, C; PIROLA, CARLOS JOSE

Peroxisome proliferator-activated receptor gamma and its coactivator-1 alpha may be associated with features of the metabolic syndrome in adolescents

Journal Molecular Endocrinology; Año: 2005 vol. 35 p. 375 - 382

PORTO, PATRICIA INES; GARCIA , SILVIA INES; DIEUZEIDE, G; GONZALEZ, C; LANDA, MARIA SILVINA; PIROLA, CARLOS JOSE

Clinical features of the metabolic syndrome in adolescents: minor role of the Trp64Arg beta3-adrenergic receptor gene variant.

PEDIATRIC RESEARCH; Año: 2004 vol. 55 p. 836 - 841

GARCIA , SILVIA INES; GARFUNKEL, VA; PORTO, PATRICIA INES; DIEUZEIDE, G; KIRSZNER, T; Y PLOTQUIN,; SPATARO, RJ; GONZALEZ, C; PIROLA, CARLOS JOSE

Hyperhomocysteinemia but not MTHFR genotype is associated with young-onset essential hypertension.

JOURNAL OF HUMAN HYPERTENSION; Año: 2003 vol. 17 p. 361 - 364

PORTO, PATRICIA INES; GARCIA , SILVIA INES; DIEUZEIDE, G; GONZALEZ, C; PIROLA, CARLOS JOSE

Renin-angiotensin-aldosterone system loci and multilocus interactions in young-onset essential hypertension.

CLINICAL AND EXPERIMENTAL HYPERTENSION; Año: 2003 vol. 25 p. 117 - 130

GARCIA , SILVIA INES; LANDA, MARIA SILVINA; PORTO, PATRICIA INES; SCHUMAN, MARIANO LUIS; FINKIELMAN, SAMUEL; PIROLA, CARLOS JOSE

Thyrotropin-releasing hormone decreases leptin and mediates the leptin-induced pressor effect.

HYPERTENSION; Año: 2002 vol. 39 p. 491 - 495

GARCIA , SILVIA INES; PORTO, PATRICIA INES; DIEUZEIDE, G; LANDA, MARIA SILVINA; KIRSZNER, T; Y PLOTQUIN,; GONZALEZ, C; PIROLA, CARLOS JOSE

Thyrotropin-releasing hormone receptor (TRHR) gene is associated with essential hypertension.

HYPERTENSION; Año: 2001 vol. 38 p. 683 - 687

GARCIA , SILVIA INES; ALVAREZ, AZUCENA LAURA; PORTO, PATRICIA INES; GARFUNKEL, VA; FINKIELMAN, SAMUEL; PIROLA, CARLOS JOSE

Antisense inhibition of thyrotropin-releasing hormone reduces arterial blood pressure in spontaneously hypertensive rats.

HYPERTENSION; Año: 2001 vol. 37 p. 365 - 370

GARCIA , SILVIA INES; PORTO, PATRICIA INES; MARTINEZ, VERONICA; ALVAREZ, AZUCENA LAURA; FINKIELMAN, SAMUEL; PIROLA, CARLOS JOSE

Expression of TRH and TRH-like peptides in a human glioblastoma-astrocytoma cell line (U-373-MG).

JOURNAL OF ENDOCRINOLOGY; Año: 2000 vol. 166 p. 697 - 703

GARCIA , SILVIA INES; CLEMENS, TL; FAGIN, JA; FINKIELMAN, SAMUEL; PIROLA, CARLOS JOSE

Parathyroid hormone-related protein expression in vascular smooth muscle of spontaneously hypertensive rats: evidence for lack of response to angiotensin II.

JOURNAL OF HYPERTENSION; Año: 1998 vol. 16 p. 1467 - 1474

GRILLO, CA; SARAVIA, FE; FERRINI, M; PIROLI, G; ROIG, P; GARCIA , SILVIA INES; DE KLOET, ER; DE NICOLA, AF

Increased expression of magnocellular vasopressin mRNA in rats with deoxycorticosterone-acetate induced salt appetite.

NEUROENDOCRINOLOGY; Año: 1998 vol. 68 p. 105 - 115

GARCIA , SILVIA INES; PORTO, PATRICIA INES; ALVAREZ, AZUCENA LAURA; MARTINEZ, VERONICA; SHAURLI, D; FINKIELMAN, SAMUEL; PIROLA, CARLOS JOSE

Central overexpression of the TRH precursor gene induces hypertension in rats: antisense reversal.

HYPERTENSION; Año: 1997 vol. 30 p. 759 - 766

DELORENZI, A; PEDREIRA, ME; ROMANO, A; GARCIA , SILVIA INES; PIROLA, CARLOS JOSE; NAHMOD, VE; MALDONADO, H

Angiotensin II enhances long-term memory in the crab Chasmagnathus.

BRAIN RESEARCH BULLETIN; Año: 1996 vol. 41 p. 211 - 220

GARCIA , SILVIA INES; DABSYS, SM; MARTINEZ, VERONICA; DELORENZI, A; SANTAJULIANA, D; NAHMOD, VE; FINKIELMAN, SAMUEL; PIROLA, CARLOS JOSE

Thyrotropin-releasing hormone hyperactivity in the preoptic area of spontaneously hypertensive rats.

HYPERTENSION; Año: 1995 vol. 26 p. 1105 - 1110

GARCIA , SILVIA INES; DABSYS, SM; SANTAJULIANA, D; DELORENZI, A; FINKIELMAN, SAMUEL; NAHMOD, VE; PIROLA, CARLOS JOSE

Interaction between thyrotrophin-releasing hormone and the muscarinic cholinergic system in rat brain.

JOURNAL OF ENDOCRINOLOGY; Año: 1992 vol. 134 p. 215 - 219

GARCIA , SILVIA INES; PIROLA, CARLOS JOSE; DABSYS, SM; SANTAJULIANA, D; DELORENZI, A; FINKIELMAN, SAMUEL; NAHMOD, VE

The cholinergic system participates in thyrotropin-releasing hormone (TRH) regulation.

NEUROSCIENCE LETTERS; Año: 1992 vol. 135 p. 1 - 1

GARCIA , SILVIA INES; FANELLI, M; NAHMOD, VE; TORRES, N; SANTAJULIANA, D; FINKIELMAN, SAMUEL; PIROLA, CARLOS JOSE

Brain amines in glucocorticoid-induced hypertension in the rat.

NEUROSCIENCE LETTERS; Año: 1992 vol. 135 p. 189 - 192