INTECIN 20395
INSTITUTO DE TECNOLOGIAS Y CIENCIAS DE LA INGENIERIA "HILARIO FERNANDEZ LONG"
Unidad Ejecutora - UE
artículos
Título:
POLYURETHANE/POLY(2-(DIETHYL AMINO) ETHYLMETHACRYLATE): A POLYMERIC BLEND FOR DRUG DELIVERY APPLICATIONS
Autor/es:
DEBANDI M.V.; FRANCOIS N.J.; ECHEVERRÍA M.G.; PARDINI O.R.; DARAIO M.E.; AMALVY J.I.
Revista:
AAPS PHARMSCITECH
Editorial:
Springer
Referencias:
Año: 2011 p. 1 - 4
ISSN:
1530-9932
Resumen:
A previous study of 2-(diethyl amino) ethylmethacrylate (DEA)-based microgels (1) shows that they are film forming. A simple way to improve the physical characteristics of films formed from pure polyDEA (PDEA) is by blending PDEA with polymers like polyurethanes (PU) that also reduces the cost of the material. In this work, blends 50:50 of PU and PDEA were prepared and characterized for water swelling capacity, water vapor transmission and in vitro drug release using theophylline as delivery marker.
