IQUIMEFA   05518
INSTITUTO QUIMICA Y METABOLISMO DEL FARMACO
Unidad Ejecutora - UE
artículos
Título:
Development of sol-gel hybrid materials for whole cell immobilization
Autor/es:
MARTÍN FEDERICO DESIMONE; GISELA SOLANGE ALVAREZ; MARÍA LUCIA FOGLIA; LUIS EDUARDO DIAZ
Revista:
Recent Patent on Biotechnology
Editorial:
Bentham Science Publishers
Referencias:
Año: 2009 vol. 3 p. 55 - 60
ISSN:
1872-2083
Resumen:
The development of a good biocompatible matrix for immobilization of cells is very crucial for improving the performance of functional biohybrids. The synthesis of solid inorganic materials from alkoxide, aqueous and polyol-modified silanes routes, as well as the incorporation of organic polymers, are further areas being developed to improve the viability of encapsulated cells. This emerging field of material science has generated considerable and increasing interest during the past decade. Recent advances in the field involving biomaterials, biohybrids, and functional nanomaterials provided novel materials, which have gained the attention of the scientific community, Governments and industrial companies. Overall, this review is intended to give an overview on the current state of the art of the patents associated to the immobilization of whole living cells in sol-gel derived hybrid materials and to describe the major challenges to be addressed in the forthcoming years.