IQUIMEFA   05518
INSTITUTO QUIMICA Y METABOLISMO DEL FARMACO
Unidad Ejecutora - UE
artículos
Título:
Sol-gel Encapsulation of Biomolecules and Cells for Medicinal Applications
Autor/es:
X WANG; N BEN AHMED; GS ALVAREZ; MV TUTTOLOMONDO; C HÉLARY; MF DESIMONE; T CORADIN
Revista:
Current Topics in Medicinal Chemistry
Editorial:
BENTHAM SCIENCE PUBL LTD
Referencias:
Lugar: Oak Park; Año: 2015 vol. 15 p. 233 - 244
ISSN:
1568-0266
Resumen:
The sol-gel process provides a robust and versatile technology for the immobilization of biologicals. A wide range of inorganic, composites and hybrid materials can be prepared to encapsulate molecular drugs, proteins, antibodies/antigens, enzymes, nucleic acids, prokaryotic and eukaryotic cells into bulk gels, particles and films. This review describes the applications of sol-gel encapsulation relevant to medicinal chemistry focusing on the recent development of biosensors as well as systems for production, screening and delivery of bioactive compounds and biomaterials.