Composition and antifungal activity of the essential oil from aerial parts of Zuccagnia punctata

SANDRA L. ALVAREZ; ADRIANA CORTADI; MIGUEL A. JUAREZ; ELISA PETENATTI; FELIX TOMI; JOSEPH CASANOVA; CATALINA M. VAN BAREN; SUSANA ZACCHINO; ROSER VILA

PHYTOCHEMISTRY LETTERS

ELSEVIER SCIENCE BV

Lugar: Amsterdam; Año: 2012 vol. 5 p. 194 - 199

1874-3900

The essential oils from aerial parts of nine populations of Zuccagnia punctata Cav. (Fabaceae) were obtained by hydrodistillation and analyzed by GC–FID, GC–MS and 13C NMR. A total of 80 constituents,mainly oxygenated monoterpenes, were identified representing from 79.0 to 95.2% of the total oils which showed different composition patterns. The unusual compound ()-5,6-dehydrocamphor, the major constituent in six of the samples investigated with percentages ranging from 12.3% to 56.5%, was isolated for the first time from nature and its structure was completely defined from NMR spectrometric data. Microscope studies of leaves indicated that not only capitate glands but also non-glandular trichomes,not previously described in this species, were present on the leaf surfaces. The essential oil showed antifungal activity against the dermatophytes Microsporum gypseum,Tricophyton rubrum and T. mentagrophytes with MIC values between 15.6 and 125 mg ml1, being T. rubrum the most susceptible species.