IMBIV   05474
INSTITUTO MULTIDISCIPLINARIO DE BIOLOGIA VEGETAL
Unidad Ejecutora - UE
artículos
Título:
Polyethylenimine Functionalized with Dopamine: Characterization
Autor/es:
DOLORES RUBIANES; MIRIAM STRUMIA
Revista:
ELECTROANALYSIS
Editorial:
WILEY-V C H VERLAG GMBH
Referencias:
Año: 2010 vol. 22 p. 1200 - 1206
ISSN:
1040-0397
Resumen:
We report the chemical modification of polyethylenimine (PEI) by functionalization with dopamine (Do) using
glutaraldehyde (Glu) as a linker (PEI-Glu-Do). The new polymer was characterized by FT-IR spectroscopy, by
derivative UV-vis spectroscopy, and Cyclic Voltammetry. The PEI-Glu-Do demonstrated to have an important
electrocatalytic activity allowing an important decrease in the overvoltages for the oxidation of NADH and a
significant increase in its oxidation peaks currents. Different ratios of PEI:Do were assayed and the best response was
obtained using PEI:Glu:Do 1: 2:1. The new polymer represents an interesting and promising alternative for the
electrochemical quantification of NADH and other analytes of clinical interest, as well as for the development of new
electrochemical (bio)sensors.