INIQUI 05448
INSTITUTO DE INVESTIGACIONES PARA LA INDUSTRIA QUIMICA
Unidad Ejecutora - UE
artículos
Título:
Withanolides with Antibacterial Activity from Nicandra john-tyleriana
Autor/es:
GUTIERREZ NICOLÁS, F.; REYES, G.; AUDISIO, M.; URIBURU, M. L.; LEIVA, S.; BARBOZA G. E.; NICOTRA, V.
Revista:
JOURNAL OF NATURAL PRODUCTS
Editorial:
AMER CHEMICAL SOC
Referencias:
Lugar: Washington; Año: 2015 vol. 78 p. 250 - 257
ISSN:
0163-3864
Resumen:
Eleven new withanolides (1−11) were isolated and characterized from the aerial parts of Nicandra john-tyleriana. Five of these withanolides have an unmodified skeleton (1−5), two are acnistins (6, 7), and four are withajardins (8−11). These new isolates were fully characterized using a combination of spectroscopic techniques (including multidimensional NMR) and mass spectrometry. All compounds were evaluated for their antibacterial activity against Bacillus, Enterococcus, Escherichia, Listeria, Pseudomonas, and Staphylococcus strains.
