IQUIR 05412
INSTITUTO DE QUIMICA ROSARIO
Unidad Ejecutora - UE
artículos
Título:
Synthesis of a 3-Thiomannoside
Autor/es:
SUÁREZ, A.G.; COMBA, M. B.; SPANEVELLO, R.A.*; SAROTTI, A.M.; MANGIONE, M.I.; GIORDANO, E.D.
Revista:
ORGANIC LETTERS
Editorial:
AMER CHEMICAL SOC
Referencias:
Lugar: Washington; Año: 2016 vol. 18 p. 1748 - 1751
ISSN:
1523-7060
Resumen:
An efficient and straightforward synthesis of a novel 3-thiomannoside derivative (1,2,4,6-tetra-O-acetyl-3-S-acetyl-3-thio- β - D -mannopyranoside) was developed starting from levoglucosenone. A xanthate − thiocarbonate exchange under acidic conditions was the key step for the new C − S bond. The product was obtained enantiospecifically in very good overall yield.
