IQUIR 05412
INSTITUTO DE QUIMICA ROSARIO
Unidad Ejecutora - UE
artículos
Título:
Structural and Spectroscopic Characterization of 2,2-methylenedi-8-quinolinol dihydrochloride Dihydrate
Autor/es:
J. ZINCZUK, O.E. PIRO, E.E. CASTELLANO, E.J. BARAN
Revista:
JOURNAL OF MOLECULAR STRUCTURE
Editorial:
Elsevier
Referencias:
Lugar: Salford; Año: 2008 vol. 892 p. 216 - 219
ISSN:
0022-2860
Resumen:
The crystal structure of the title compound, a promising ligand for chelatoterapies in the treatment ofAlzheimers disease, has been determined by single crystal X-ray diffractometry. The compound crystallizedin the monoclinic space group C2/c with Z = 4. The dimeric 8-quinolinol molecule is sited on a crystallographictwofold axis passing through the CH2 carbon atom that links the symmetry related molecularhalves, giving rise to a two-bladed propeller-like conformation. The 1H and 13C NMR as well as the FT-IRand Raman spectra of the compound were also recorded and are briefly discussed. Some comparisonswith spectra of related species are made.
