IQUIR   05412
INSTITUTO DE QUIMICA ROSARIO
Unidad Ejecutora - UE
artículos
Título:
Versatile and Efficient Solid-Supported Synthesis of C3-Anchored Monocyclic b-Lactam Derivatives
Autor/es:
LUCIANA MENDEZ; SEBASTIÁN A. TESTERO; ERNESTO G. MATA
Revista:
J. Comb. Chem.
Editorial:
ACS
Referencias:
Año: 2007 vol. 9 p. 189 - 192
ISSN:
1520-4766
Resumen:
A novel and efficient approach, based on the immobilization of the carboxylic acid intermediate, is described for the preparation of synthetically useful â-lactam derivatives on solid support. The applied strategy allows the introduction of diversity at N-1 and C-4 of the â-lactam ring with good overall isolated yields of the desired products.