IQUIR 05412
INSTITUTO DE QUIMICA ROSARIO
Unidad Ejecutora - UE
artículos
Título:
Discovery of a Beta-glucosidase inhibitor from a Chemically Engineered Extract prepared through sulfonylation
Autor/es:
SALAZAR, MARIO; MICHELONI, OSCAR; ESCALANTE, ANDREA M.; FURLÁN, RICARDO L.E.
Revista:
MOLECULAR DIVERSITY
Editorial:
SPRINGER
Referencias:
Lugar: New York; Año: 2011 vol. 15 p. 713 - 719
ISSN:
1381-1991
Resumen:
A semisynthetic beta-glucosidase inhibitor was identified from a chemically engineered extract prepared by reaction with benzenesulfonyl chloride. The structure includes a natural histamine portion and a benzenesulfonyl portion introduced during the diversification step. This structure could be detected and characterized by LC-MS/MS experiments.
