Data of H 2 O 2 release from AQP8-knockdown rat hepatocyte mitochondria

DANIELLI, MAURO; MARINELLI, RAÚL A.; CAPIGLIONI, ALEJO M.; MARRONE, JULIETA

Data in Brief

Elsevier Inc.

Año: 2019 vol. 23

This article reports experimental data related to the research article entitled ?Mitochondrial aquaporin-8 is involved in SREBP-controlled hepatocyte cholesterol biosynthesis? [Danielli et al., 2019]. We present data about hydrogen peroxide (H 2 O 2 ) release from mitochondria isolated from rat hepatocytes with or without silencing of aquaporin-8 (AQP8) protein expression. The rate of mitochondrial H 2 O 2 release (pmoles/min/mg mitochondrial protein) was found to be decreased by about 50% in AQP8-knockdown mitochondria.