Radical Based Arylation Methods

SANTIAGO E. VAILLARD, BIRTE SCHULTE AND ARMIDO STUDER

Modern Arylation Methods

Wiley & Sons

Lugar: Weinhein; Año: 2009; p. 475 - 511

Most of the radical reactions can be conducted under mild conditions. In contrast to ionic reactions and many transition-metal mediated processes most of the functional groups are tolerated under radical conditions. Moreover, radical reactions can be performed in various solvents; even water is tolerated as a reaction medium. These facts among others make radical processes highly useful for arylations. Radical arylations can be performed by SRN1 type reactions, by homolytic aromatic substitutions, and by reactions of aryl radicals with various radical acceptors. In the present book article we first focus on SRN1 type reactions . The second and larger part deals with homolytic aromatic substitutions