INCAPE 05401
INSTITUTO DE INVESTIGACIONES EN CATALISIS Y PETROQUIMICA "ING. JOSE MIGUEL PARERA"
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Enantioselective hydrogenation of ethyl pyruvate over ionic exchange resins supported catalyts
Autor/es:
CARRARA, N.; LEDERHOS, C.; POLETT RUIZ, D.; MENDOW, G.; BETTI, C.; VERA, C.; BADANO, J.; MACCARRONE, M.J.; QUIROGA , M.
Lugar:
Beijing
Reunión:
Congreso; 16th International Congress on Catalysis; 2016
Institución organizadora:
The Catalysis Society of China
Resumen:
The use of noble metal catalysts supported on ionic exchange resins for the enantioselective hydrogenation of ethyl pyruvate was studied. High activity and selectivity values were obtained. Pt was the best active metal, followed by Pd,Au and Rh. The use of a Pt-Cinchonidine system produced (R)-ethyl lactate enantiomeric excess. Pt-Cinchonine yielded the unwanted (S) enantiomer. The reaction was found to be structure sensitive and the importance of the metalparticle size for the adsorption of the chiral modiffier was proved. Sintering of the metal particles during the nitrite reduction reaction seemingly occurs with migration of the particles to the surface layers and a decrease of the dispersion. There exists an optimal particle size that maximizes the enantiomeric excess, corresponding to 24 h sintering treatment time in the current experiments.
