INCAPE   05401
INSTITUTO DE INVESTIGACIONES EN CATALISIS Y PETROQUIMICA "ING. JOSE MIGUEL PARERA"
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Tandem Hydrogenation-dehydration Reactions for the Synthesis of Olefins from Aromatic Ketones
Autor/es:
NICOLÁS M. BERTERO; CARLOS R. APESTEGUÍA; ALBERTO J. MARCHI
Lugar:
Detroit, Estados Unidos
Reunión:
Congreso; 22nd NAM Catalysis Meeting; 2011
Institución organizadora:
North American Catalysis Society
Resumen:
The synthesis of fine
chemicals usually involves several consecutive-parallel reaction steps that
often employ as many batch reactors as chemical transformations are needed in
the global synthesis. This methodology frequently allows the successful
selective synthesis of the desired product, but involves high operative costs.
Besides, the multi-step batch processes require large volumes of solvents,
salts and acid or basic liquids thereby generating significant amount of wastes
that need to be either recycled or removed. Thus, it is of environmental and
economic interest to develop novel integrated methodologies allowing one-pot
synthesis processes via the catalytic promotion of tandem reactions. The
two-steps conversion of aromatic ketones to aromatic olefins that involves
consecutive hydrogenation-dehydration reactions has been studied using
homogeneous catalysis for obtaining valuable products such as
2,6-dimethylnaphtalene and indenes. Here, we investigated the use of solid
catalysts for the one-pot synthesis of aromatic olefins from aromatic ketones
via tandem hydrogenation-dehydration reactions. Definitions of tandem process
are not unanimous in the literature. We used the concept of tandem consecutive
reactions, wherein the first step is necessary but not sufficient for the
tandem process, and changes in reaction conditions are also required to
facilitate propagation. The conversion of acetophenone (AP) to styrene (STY)
was used as model reaction. The AP hydrogenation and 1-phenylethanol (PHE)
dehydration reactions were first studied separately in order to select the best
catalysts for achieving high conversions and selectivities. Then, the selected
catalysts were employed for investigating the one-pot synthesis of STY from AP.