INCAPE 05401
INSTITUTO DE INVESTIGACIONES EN CATALISIS Y PETROQUIMICA "ING. JOSE MIGUEL PARERA"
Unidad Ejecutora - UE
artículos
Título:
Novel application of HKUST-1 metal-organic framework as antifungal: Biological tests and physicochemical characterizations
Autor/es:
CHIERICATTI CAROLINA; BASILICO JUAN CARLOS; BASILICO MARIA L ZAPATA; J. M. ZAMARO
Revista:
MICROPOROUS AND MESOPOROUS MATERIALS
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2012 vol. 162 p. 60 - 63
ISSN:
1387-1811
Resumen:
The HKUST-1 metal-organic framework (MOF) was successfully applied as a biocidal material against representative yeast and mold. The synthesized MOF showed a strong antifungal effect against Saccharomices cerevisiae for which the growth was completely inhibited, whereas the growth of Geotrichum candidum was reduced from 6.16 CFU ml-1 to 1.29 CFU ml-1. The antifungal action was related to copper ions released into the culture medium due to a progressive degradation of the crystalline structure of the material that involved the formation of surface extra-framework Cu(I). This study shows the potential of using copper-based metal-organic frameworks for a controlled release of biologically active copper ions.
