Localized corrosion and cytotoxic effect of ASTM F745 in culture medium

J. E. GRAU; D. CASTROGIOVANNI; C. I. ELSNER; R. W. GREGORUTTI; J. PARISI

Darmstadt

Congreso; European Congress Materials Science Engineering and Exhibition on Advanced Materials and Processes; 2018

Austenitic stainless steels (specification ASTM F138/139/745 are widely used for load bearing partial and total joint replacements, and post trauma reconstructive surgeries. These biomaterials contain Cr and Ni, which would cause different systemic-toxic reactions during the time that the device is implanted in the body. In particular, Ni is known as allergenic agent and has some carcinogenic potential.