IMEX 05356
INSTITUTO DE MEDICINA EXPERIMENTAL
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
High prevalence of recurrent F8 genotypes in the first series of Argentine patients with mild hemophilia A
Autor/es:
ROSSETTI LC; ABELLEYRO MM; CARLOS D. DE BRASI; MARCHIONE VD; SANCHEZ LUCERO A; RADIC CP; NEME D
Lugar:
Melbourne
Reunión:
Congreso; ISTH 2019; 2019
Institución organizadora:
International Society on Thrombosis and Haemostasis
Resumen:
Background: Hemophilia A (HA),the commonest X-linked coagulopathy, is associated with deleterious variants inthe F8. Mild-HA patients show clottingactivities of factor VIII (FVIII:C) ranging 5-40 IU/dL. Although mild-HArepresents 35-40% of total HA cases, they are much less studied and genotypedthan severe cases worldwide. Both the theoretical basis and the scarce relatedliterature indicate that mild- and severe-HA (FVIII:C
