IMEX 05356
INSTITUTO DE MEDICINA EXPERIMENTAL
Unidad Ejecutora - UE
artículos
Título:
Update on the Functionality of Thymic Stromal Lymphopoietin and its Interaction with Dendritic Cells, to Trigger a Pro or Anti-Inflammatory Status
Autor/es:
VANINA A FONTANA; GABRIELA SALAMONE; JUAN VALENTIN CORONEL; MÓNICA VERMEULEN; JULIETA ALCAIN
Revista:
Journal of Allergy Research
Editorial:
SciTech Central Inc.
Referencias:
Año: 2020
ISSN:
2642-326X
Resumen:
Thymic stromal lymphopoietin (TSLP) is a cytokine produced primarily by activated epithelial cells of the lung, skin and intestine. The foremost property of this cytokine is to condition dendritic cells (DC) to initiate type 2 responses, and consequently to develop a wide range of related disease, including asthma, atopic dermatitis, and allergic responses. However, TSLP is also associated with regulatory and homeostatic processes. The objective of this review is to provide a summary overview of the variety of functions found in this cytokine.
