MACNBR 00242
MUSEO ARGENTINO DE CIENCIAS NATURALES "BERNARDINO RIVADAVIA"
Unidad Ejecutora - UE
artículos
Título:
Identification of sulfated steroidal glycosides from the starfish Heliaster helianthus by electrospray ionization mass spectrometry
Autor/es:
MAIER, M.S.; CENTURIÓN, R.; MUNIAIN, C.; HADDAD, R.; EBERLIN, M.N.
Revista:
Arkivoc
Editorial:
Arkat USA, Inc.
Referencias:
Año: 2007 vol. VII p. 301 - 309
ISSN:
1424-6376
Resumen:
The starfish Heliaster helianthus contains Thornasteroside A (1) and Helianthoside (2) and itsisomer (3) as the major sulfated steroidal glycosides. Saponin containing fractions obtained bypurification of extracts of H. helianthus induced escape reactions and mortality in the limpetsSiphonaria lessoni and Fissurella radiosa. ESI-MS and ESI-MS/MS were successfully appliedto the rapid screening of two cytotoxic fractions obtained by purification of the ethanolic extractsof arms and central disks dissected from H. helianthus. Three major compounds were identified,together with minor sulfated steroidal mono- and diglycosides of polyhydroxysteroids.
