MACNBR   00242
MUSEO ARGENTINO DE CIENCIAS NATURALES "BERNARDINO RIVADAVIA"
Unidad Ejecutora - UE
artículos
Título:
Identification of sulfated steroidal glycosides from the starfish Heliaster helianthus by electrospray ionization mass spectrometry
Autor/es:
MAIER, M.; CENTURIÓN, R.; MUNIAIN, C.; HADDAD, R.; EBERLIN, N.
Revista:
Arkivoc
Editorial:
Arkat USA
Referencias:
Año: 2006 vol. vii p. 301 - 301
ISSN:
1424-6376
Resumen:
The starfish Heliaster helianthus contains Thornasteroside A (1) and Helianthoside A (2) and its isomer (3) as the major sulfated steroidal glycosides. Saponin containing fractions obtained by purification of extracts of H. helianthus induced escape reactions and mortality in the limpets Siphonaria lessoni and Fissurella radiosa. ESI-MS and ESI-MS/MS were successfully applied to the rapid screening of two cytotoxic fractions obtained by purification of the ethanolic extracts of arms and central disks dissected from H. helianthus. Three major compounds were identified, together with minor sulfated steroidal mono- and diglycosides of polyhydroxysteroids.