INVESTIGADORES
ALONSO Leonardo Gabriel
congresos y reuniones científicas
Título:
Deamidation drives molecular aging of the SARS-CoV-2 spike receptor-binding motif.
Autor/es:
ALONSO LEONARDO
Lugar:
Janeiro-na-Madeira
Reunión:
Workshop; Janeiro-na-Madeira Winter Summer School 2022; 2022
Institución organizadora:
Lectures and actions for EU consortia TopSpec, ARIADNE and ALLODD
Resumen:
By default, ASN deamidation is conceived as a degradative reaction that is detrimental for protein function and stability.Exceptionally, deamidation gains importance in biologics and vaccine development when deamidating-prone Asn residues are located, by chance, in protein-protein binding interfaces or in antigenically relevant epitopes that critically affect protein performance.
