JULIÁN TARSITANO; LILA Y. RAMIS; LEONARDO G. ALONSO; DANIELA M. RUSSO; ANGELES ZORREGUIETA

RapD Is a Multimeric Calcium-Binding Protein That Interacts With the Rhizobium leguminosarum Biofilm Exopolysaccharide, Influencing the Polymer Lengths

Frontiers in Microbiology; Lugar: Berlin; Año: 2022

TRABUCCHI, ALDANA; BOMBICINO, SILVINA SONIA; MARFÍA, JUAN IGNACIO; SABLJIC, ADRIANA VICTORIA; IACONO, RUBÉN FRANCISCO; SMITH, IGNACIO; CALLUM, GREGORIO JUAN MC; TARGOVNIK, ALEXANDRA MARISA; WOLMAN, FEDERICO JAVIER; FINGERMANN, MATÍAS; ALONSO, LEONARDO GABRIEL; MIRANDA, MARÍA VICTORIA; VALDEZ, SILVINA NOEMÍ

Novel bridge multi-species ELISA for detection of SARS-CoV-2 antibodies

JOURNAL OF IMMUNOLOGICAL METHODS; Año: 2022

ESPERANTE, S.A.; ALVAREZ-PAGGI, D.; SALGUEIRO, M.; DESIMONE, M.F.; DE OLIVEIRA, G.A.P.; ARÁN, M.; GARCÍA-PRADO, J.; APTEKMANN, A.A.; VENTURA, S.; ALONSO, L.G.; PRAT-GAY, G.

A finely tuned interplay between calcium binding, ionic strength and pH modulates conformational and oligomerization equilibria in the Respiratory Syncytial Virus Matrix (M) protein

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS; Año: 2022

POODTS, JOAQUÍN; SMITH, IGNACIO; BIRENBAUM, JOAQUÍN MANUEL; RODRIGUEZ, MARÍA SOL; MONTERO, LUCIANO; WOLMAN, FEDERICO JAVIER; MARFÍA, JUAN IGNACIO; VALDEZ, SILVINA NOEMÍ; ALONSO, LEONARDO GABRIEL; TARGOVNIK, ALEXANDRA MARISA; MIRANDA, MARÍA VICTORIA

Improved Expression of SARS-CoV-2 Spike RBD Using the Insect Cell-Baculovirus System

Viruses; Lugar: Basel; Año: 2022 vol. 14

SMITH, IGNACIO; MC CALLUM, GREGORIO JUAN; SABLJIC, ADRIANA VICTORIA; MARFIA, JUAN IGNACIO; BOMBICINO, SILVINA SONIA; TRABUCCHI, ALDANA; IACONO, RUBEN FRANCISCO; BIRENBAUM, JOAQUÍN MANUEL; VAZQUEZ, SUSANA CLAUDIA; MINOIA, JUAN MAURICIO; CASCONE, OSVALDO; LÓPEZ, MARÍA GABRIELA; TABOGA, OSCAR; TARGOVNIK, ALEXANDRA MARISA; WOLMAN, FEDERICO JAVIER; FINGERMANN, MATÍAS; ALONSO, LEONARDO GABRIEL; NOEMÍ, VALDEZ SILVINA; MIRANDA, MARÍA VICTORIA

RAPID AND COST‐EFFECTIVE PROCESS BASED ON INSECT LARVAE FOR SCALE‐UP PRODUCTION OF SARS‐COV‐2 SPIKE PROTEIN FOR SEROLOGICAL COVID‐19 TESTING

BIOENGINEERING AND BIOTECHNOLOGY; Año: 2021

RAMIRO LORENZO; LUCAS A. DEFELIPE; LUCIO ALIPERTI; STEPHAN NIEBLING; TÂNIA F. CUSTÓDIO; CHRISTIAN LÖW; JENNIFER J. SCHWARZ; KIM REMANS; PATRICIO O. CRAIG; LISANDRO H. OTERO; SEBASTIÁN KLINKE; MARÍA GARCÍA-ALAI; IGNACIO E. SÁNCHEZ; LEONARDO G. ALONSO

Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif

JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2021

LORENZO, RAMIRO; LEONETTI, CÉSAR O; ALONSO, LEONARDO G; SÁNCHEZ, IGNACIO E

NGOME-Lite: Proteome-wide prediction of spontaneous protein deamidation highlights differences between taxa

METHODS; Año: 2020

ALVAREZ-PAGGI, DAMIÁN; LORENZO, JUAN RAMIRO; CAMPOREALE, GABRIELA; MONTERO, LUCIANO; SÁNCHEZ, IGNACIO E; DE PRAT GAY, GONZALO; ALONSO, LEONARDO G

Topology Dictates Evolution of Regulatory Cysteines in a Family of Viral Oncoproteins

MOLECULAR BIOLOGY AND EVOLUTION; Año: 2019

JULIETA CONCI; ALVAREZ-PAGGI, DAMIÁN; DE OLIVERA GAP; PAGANI TD; ESPERANTE SEBASTIAN; BORKOSKY, SILVIA S.; ARAN MARTIN; ALONSO LEONARDO G.; MOHANA-BORGES R; DE PRAT GAY G

Conformational Isomerization Involving Conserved Proline Residues Modulates Oligomerization of the NS1 Interferon Response Inhibitor from the Syncytial Respiratory Virus.

BIOCHEMISTRY; Lugar: Washington; Año: 2019

GABRIELA CAMPOREALE; JUAN R. LORENZO; MARIA G. THOMAS; EDGARDO SALVATIERRA; SILVIA S. BORKOSKY; MARIKENA G. RISSO; IGNACIO E. SÁNCHEZ; GONZALO DE PRAT GAY; LEONARDO G. ALONSO

Degenerate cysteine patterns mediate two redox sensing mechanisms in the papillomavirus E7 oncoprotein

Redox Biology; Lugar: Amsterdam; Año: 2017 vol. 11 p. 38 - 50

BORKOSKY, SILVIA S.; CAMPOREALE, GABRIELA; CHEMES, LUCÍA B.; RISSO, MARIKENA; NOVAL, MARÍA GABRIELA; SÁNCHEZ, IGNACIO E.; ALONSO, LEONARDO G.; DE PRAT GAY, GONZALO

Hidden Structural Codes in Protein Intrinsic Disorder

BIOCHEMISTRY; Año: 2017

J. RAMIRO LORENZO; ALONSO LEONARDO G.; IGNACIO E. SÁNCHEZ

Prediction of Spontaneous Protein Deamidation from Sequence-Derived Secondary Structure and Intrinsic Disorder.

PLOS ONE; Lugar: San Francisco; Año: 2015 vol. 10

N RAMIREZ; F. GUERRA; G. CAMPOREALE; S QUINTANA; LB DIAZ; N CUNEO; J VILLACORTA HIDALGO; SA TATTI; LG ALONSO; SS BORKOSKY; G PRAT GAY; L PALAORO

Expressions of E2 and E7-HPV16 proteins in pre-malignant and malignant lesions of the uterine cervix.

BIOTECHNIC AND HISTOCHEMISTRY; Lugar: London; Año: 2015 vol. 8 p. 1 - 8

LUCÍA B. CHEMES; GABRIELA CAMPOREALE; IGNACIO E. SÁNCHEZ; DE PRAT-GAY GONZALO; ALONSO LEONARDO G.

Cysteine-Rich Positions Outside the Structural Zinc Motif of Human Papillomavirus E7 Provide Conformational Modulation and Suggest Functional Redox Roles

BIOCHEMISTRY; Lugar: Washington; Año: 2014 vol. 53 p. 1680 - 1696

KRICK TERESA; VERSTRAETE N; ALONSO L; SHUB DA; FERREIRO DU; SHUB, MICHAEL; SÁNCHEZ IE

Amino acid metabolism conflicts with protein diversity.

MOLECULAR BIOLOGY AND EVOLUTION; Lugar: Oxford; Año: 2014

LUCÍA B. CHEMES; JULIANA GLAVINA; LEONARDO G. ALONSO; CRISTINA MARINO-BUSLJE; GONZALO DE PRAT-GAY; IGNACIO E. SÁNCHEZ

Sequence Evolution of the Intrinsically Disordered and Globular Domains of a Model Viral Oncoprotein

PLOS ONE; Lugar: San Francisco; Año: 2012 vol. 7 p. 1 - 9

CLARA SMAL; LEONARDO G. ALONSO; DIANA E. WETZLE; ANGELES HEER; GONZALO DE PRAT GAY

Ordered Self-Assembly Mechanism of a Spherical Oncoprotein Oligomer Triggered by Zinc Removal and Stabilized by an Intrinsically Disordered Domain

PLOS ONE; Lugar: San Francisco; Año: 2012 p. 1 - 10

ALONSO LEONARDO; MARIA LAURA CERUTTI; MARIKENA RISSO; MARIANGELES GONZALEZ; GABRIELA CAMPOREALE; GONZALO DE PRAT GAY

DESARROLLO DE UNA VACUNA PROFILACTICA DE SEGUNDA GENERACION CONTRA EL PAPILOMAVIRUS HUMANO

MEDICINA (BUENOS AIRES); Lugar: Buenos Aires; Año: 2011 vol. 71 p. 261 - 266

ANGELES HEER; ALONSO LEONARDO G.; DE PRAT-GAY GONZALO

E6*, the 50 Amino Acid Product of the Most Abundant Spliced Transcript of the E6 Oncoprotein in High-Risk Human Papillomavirus, Is a Promiscuous Folder and Binder

BIOCHEMISTRY; Lugar: Washington; Año: 2011 p. 1376 - 1383

CERUTTI M.L; ALONSO L.G; SILVIO TATTI; DE PRAT GAY, G

Long-lasting immunoprotective and therapeutic effects of a hyperstable E7 oligomer based vaccine in a murine human papillomavirus tumor model.

INTERNATIONAL JOURNAL OF CANCER. JOURNAL INTERNATIONAL DU CANCER.; Año: 2011 p. 1813 - 1820

KARINA DANTUR; LEONARDO ALONSO; EDUARDO CASTAÑO; LAURA MORELLI; JUAN MANUEL CENTENO-CROWLEY; SUSANA VIGHI; GONZALO DE PRAT-GAY

ytosolic accumulation of HPV16 E7 oligomers supports different transformation routes for the prototypic viral oncoprotein: the amyloid-cancer connection

INTERNATIONAL JOURNAL OF CANCER. JOURNAL INTERNATIONAL DU CANCER.; Lugar: NJ (USA); Año: 2009 vol. 125 p. 1902 - 1911

SMAL C; WETZLER DE; DANTUR KI; CHEMES LB; GARCIA-ALAI MM; DELLAROLE M; ALONSO LG; GASTON K; DE PRAT-GAY G.

he human papillomavirus E7-E2 interaction mechanism in vitro reveals a finely tuned system for modulating available E7 and E2 proteins

BIOCHEMISTRY; Lugar: Washington; Año: 2009 vol. 48 p. 11939 - 11949

RAMIRO E. LLOVERA; MATÍAS DE TULLIO; LEONARDO G. ALONSO; MALCOLM A. LEISSRING; SERGIO B. KAUFMAN; ALEX E. ROHER; GONZALO DE PRAT GAY; LAURA MORELLI; EDUARDO M. CASTAÑO

The Catalytic Domain of Insulin-degrading Enzyme Forms a Denaturant-resistant Complex with Amyloid β Peptide IMPLICATIONS FOR ALZHEIMER DISEASE PATHOGENESIS

JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda; Año: 2008 vol. 283 p. 17039 - 17048

HABER CL; GOTTIFREDI V; LLERA AS; SALVATIERRA E; PRADA F; ALONSO L; SAGE EH; PODHAJCER OL

SPARC modulates the proliferation of stromal but not melanoma cells unless endogenous SPARC expression is downregulated

INTERNATIONAL JOURNAL OF CANCER. JOURNAL INTERNATIONAL DU CANCER.; Lugar: NJ; Año: 2007 vol. 122 p. 1465 - 1475

MARIA M. GARCÍA-ALAI; LEONARDO G. ALONSO; GONZALO DE PRAT-GAY

The N-Terminal Module of HPV16 E7 Is an Intrinsically Disordered Domain That Confers Conformational and Recognition Plasticity to the Oncoprotein

BIOCHEMISTRY; Año: 2007 vol. 46 p. 10405 - 10412

ALONSO LEONARDO G.; SMAL CLARA; GARCIA-ALAI MARIA M.; CHEMES LUCIA; SALAME MARCELO; DE PRAT-GAY GONZALO

Chaperone holdase activity of human papillomavirus E7 oncoprotein.

BIOCHEMISTRY; Año: 2006 vol. 45 p. 657 - 667

DE PRAT-GAY G.; NADRA ALEJANDRO D.; CORRALES-IZQUIERDO FJ; ALONSO LEONARDO G.; FERREIRO DU; MOK YK

The folding mechanism of a dimeric beta-barrel domain

JOURNAL OF MOLECULAR BIOLOGY; Año: 2005 vol. 351 p. 672 - 682

MORELLI L; LLOVERA RE; ALONSO LEONARDO G; FRANGIONE B; DE PRAT-GAY G; GHISO J; CASTANO EM

Insulin-degrading enzyme degrades amyloid peptides associated with British and Danish familial dementia

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 2005 vol. 332 p. 808 - 816

ALONSO LEONARDO G.; GARCIA-ALAI MM; SMAL C; CENTENO JM; IACONO R; CASTANO E; GUALFETTI P; DE PRAT-GAY G

The HPV16 E7 viral oncoprotein self-assembles into defined spherical oligomers.Alonso LG, Garcia-Alai

BIOCHEMISTRY; Año: 2004 vol. 43 p. 3310 - 3317

DI PIETRO SM; CENTENO JM; CERUTTI ML; LODEIRO MF; FERREIRO DU; ALONSO LEONARDO G.; SCHWARZ FP; GOLDBAUM FA; DE PRAT-GAY G

Specific antibody-DNA interaction: a novel strategy for tight DNA recognition.

BIOCHEMISTRY; Año: 2003 vol. 42 p. 6218 - 6227

CARAMELO JJ; CASTRO OA; ALONSO LEONARDO G.; DE PRAT-GAY G; PARODI AJ

UDP-Glc:glycoprotein glucosyltransferase recognizes structured and solvent accessible hydrophobic patches in molten globule-like folding intermediates

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2003 vol. 100 p. 86 - 91

ALONSO LEONARDO G; GARCIA-ALAI MM; NADRA AD; LAPENA AN; ALMEIDA FL; GUALFETTI P; PRAT-GAY GD

High-risk (HPV16) human papillomavirus E7 oncoprotein is highly stable and extended, with conformational transitions that could explain its multiple cellular binding partners

BIOCHEMISTRY; Año: 2002 vol. 41 p. 10510 - 10518

FERREIRO DU; LIMA LM; NADRA AD; ALONSO LEONARDO G; GOLDBAUM FA; DE PRAT-GAY G

Distinctive cognate sequence discrimination, bound DNA conformation, and binding modes in the E2 C-terminal domains from prototype human and bovine papillomaviruses

BIOCHEMISTRY; Año: 2000 vol. 39 p. 14692 - 14701

MOK YK; ALONSO LEONARDO G; LIMA LM; BYCROFT M; DE PRAT-GAY G

Folding of a dimeric beta-barrel: residual structure in the urea denatured state of the human papillomavirus E2 DNA binding domain

PROTEIN SCIENCE; Año: 2000 vol. 9 p. 799 - 811