INVESTIGADORES
ALONSO Leonardo Gabriel
artículos
ALVAREZ-PAGGI, DAMIÁN; LORENZO, JUAN RAMIRO; CAMPOREALE, GABRIELA; MONTERO, LUCIANO; SÁNCHEZ, IGNACIO E; DE PRAT GAY, GONZALO; ALONSO, LEONARDO G
Topology Dictates Evolution of Regulatory Cysteines in a Family of Viral Oncoproteins
MOLECULAR BIOLOGY AND EVOLUTION; Año: 2019
JULIETA CONCI; ALVAREZ-PAGGI, DAMIÁN; DE OLIVERA GAP; PAGANI TD; ESPERANTE SEBASTIAN; BORKOSKY, SILVIA S.; ARAN MARTIN; ALONSO LEONARDO G.; MOHANA-BORGES R; DE PRAT GAY G
Conformational Isomerization Involving Conserved Proline Residues Modulates Oligomerization of the NS1 Interferon Response Inhibitor from the Syncytial Respiratory Virus.
BIOCHEMISTRY; Lugar: Washington; Año: 2019
GABRIELA CAMPOREALE; JUAN R. LORENZO; MARIA G. THOMAS; EDGARDO SALVATIERRA; SILVIA S. BORKOSKY; MARIKENA G. RISSO; IGNACIO E. SÁNCHEZ; GONZALO DE PRAT GAY; LEONARDO G. ALONSO
Degenerate cysteine patterns mediate two redox sensing mechanisms in the papillomavirus E7 oncoprotein
Redox Biology; Lugar: Amsterdam; Año: 2017 vol. 11 p. 38 - 50
BORKOSKY, SILVIA S.; CAMPOREALE, GABRIELA; CHEMES, LUCÍA B.; RISSO, MARIKENA; NOVAL, MARÍA GABRIELA; SÁNCHEZ, IGNACIO E.; ALONSO, LEONARDO G.; DE PRAT GAY, GONZALO
Hidden Structural Codes in Protein Intrinsic Disorder
BIOCHEMISTRY; Año: 2017
J. RAMIRO LORENZO; ALONSO LEONARDO G.; IGNACIO E. SÁNCHEZ
Prediction of Spontaneous Protein Deamidation from Sequence-Derived Secondary Structure and Intrinsic Disorder.
PLOS ONE; Lugar: San Francisco; Año: 2015 vol. 10
N RAMIREZ; F. GUERRA; G. CAMPOREALE; S QUINTANA; LB DIAZ; N CUNEO; J VILLACORTA HIDALGO; SA TATTI; LG ALONSO; SS BORKOSKY; G PRAT GAY; L PALAORO
Expressions of E2 and E7-HPV16 proteins in pre-malignant and malignant lesions of the uterine cervix.
BIOTECHNIC AND HISTOCHEMISTRY; Lugar: London; Año: 2015 vol. 8 p. 1 - 8
LUCÍA B. CHEMES; GABRIELA CAMPOREALE; IGNACIO E. SÁNCHEZ; DE PRAT-GAY GONZALO; ALONSO LEONARDO G.
Cysteine-Rich Positions Outside the Structural Zinc Motif of Human Papillomavirus E7 Provide Conformational Modulation and Suggest Functional Redox Roles
BIOCHEMISTRY; Lugar: Washington; Año: 2014 vol. 53 p. 1680 - 1696
KRICK TERESA; VERSTRAETE N; ALONSO L; SHUB DA; FERREIRO DU; SHUB, MICHAEL; SÁNCHEZ IE
Amino acid metabolism conflicts with protein diversity.
MOLECULAR BIOLOGY AND EVOLUTION; Lugar: Oxford; Año: 2014
LUCÍA B. CHEMES; JULIANA GLAVINA; LEONARDO G. ALONSO; CRISTINA MARINO-BUSLJE; GONZALO DE PRAT-GAY; IGNACIO E. SÁNCHEZ
Sequence Evolution of the Intrinsically Disordered and Globular Domains of a Model Viral Oncoprotein
PLOS ONE; Lugar: San Francisco; Año: 2012 vol. 7 p. 1 - 9
CLARA SMAL; LEONARDO G. ALONSO; DIANA E. WETZLE; ANGELES HEER; GONZALO DE PRAT GAY
Ordered Self-Assembly Mechanism of a Spherical Oncoprotein Oligomer Triggered by Zinc Removal and Stabilized by an Intrinsically Disordered Domain
PLOS ONE; Lugar: San Francisco; Año: 2012 p. 1 - 10
ALONSO LEONARDO; MARIA LAURA CERUTTI; MARIKENA RISSO; MARIANGELES GONZALEZ; GABRIELA CAMPOREALE; GONZALO DE PRAT GAY
DESARROLLO DE UNA VACUNA PROFILACTICA DE SEGUNDA GENERACION CONTRA EL PAPILOMAVIRUS HUMANO
MEDICINA (BUENOS AIRES); Lugar: Buenos Aires; Año: 2011 vol. 71 p. 261 - 266
ANGELES HEER; ALONSO LEONARDO G.; DE PRAT-GAY GONZALO
E6*, the 50 Amino Acid Product of the Most Abundant Spliced Transcript of the E6 Oncoprotein in High-Risk Human Papillomavirus, Is a Promiscuous Folder and Binder
BIOCHEMISTRY; Lugar: Washington; Año: 2011 p. 1376 - 1383
CERUTTI M.L; ALONSO L.G; SILVIO TATTI; DE PRAT GAY, G
Long-lasting immunoprotective and therapeutic effects of a hyperstable E7 oligomer based vaccine in a murine human papillomavirus tumor model.
INTERNATIONAL JOURNAL OF CANCER. JOURNAL INTERNATIONAL DU CANCER.; Año: 2011 p. 1813 - 1820
KARINA DANTUR; LEONARDO ALONSO; EDUARDO CASTAÑO; LAURA MORELLI; JUAN MANUEL CENTENO-CROWLEY; SUSANA VIGHI; GONZALO DE PRAT-GAY
ytosolic accumulation of HPV16 E7 oligomers supports different transformation routes for the prototypic viral oncoprotein: the amyloid-cancer connection
INTERNATIONAL JOURNAL OF CANCER. JOURNAL INTERNATIONAL DU CANCER.; Lugar: NJ (USA); Año: 2009 vol. 125 p. 1902 - 1911
SMAL C; WETZLER DE; DANTUR KI; CHEMES LB; GARCIA-ALAI MM; DELLAROLE M; ALONSO LG; GASTON K; DE PRAT-GAY G.
he human papillomavirus E7-E2 interaction mechanism in vitro reveals a finely tuned system for modulating available E7 and E2 proteins
BIOCHEMISTRY; Lugar: Washington; Año: 2009 vol. 48 p. 11939 - 11949
RAMIRO E. LLOVERA; MATÍAS DE TULLIO; LEONARDO G. ALONSO; MALCOLM A. LEISSRING; SERGIO B. KAUFMAN; ALEX E. ROHER; GONZALO DE PRAT GAY; LAURA MORELLI; EDUARDO M. CASTAÑO
The Catalytic Domain of Insulin-degrading Enzyme Forms a Denaturant-resistant Complex with Amyloid β Peptide IMPLICATIONS FOR ALZHEIMER DISEASE PATHOGENESIS
JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda; Año: 2008 vol. 283 p. 17039 - 17048
HABER CL; GOTTIFREDI V; LLERA AS; SALVATIERRA E; PRADA F; ALONSO L; SAGE EH; PODHAJCER OL
SPARC modulates the proliferation of stromal but not melanoma cells unless endogenous SPARC expression is downregulated
INTERNATIONAL JOURNAL OF CANCER. JOURNAL INTERNATIONAL DU CANCER.; Lugar: NJ; Año: 2007 vol. 122 p. 1465 - 1475
MARIA M. GARCÍA-ALAI; LEONARDO G. ALONSO; GONZALO DE PRAT-GAY
The N-Terminal Module of HPV16 E7 Is an Intrinsically Disordered Domain That Confers Conformational and Recognition Plasticity to the Oncoprotein
BIOCHEMISTRY; Año: 2007 vol. 46 p. 10405 - 10412
ALONSO LEONARDO G.; SMAL CLARA; GARCIA-ALAI MARIA M.; CHEMES LUCIA; SALAME MARCELO; DE PRAT-GAY GONZALO
Chaperone holdase activity of human papillomavirus E7 oncoprotein.
BIOCHEMISTRY; Año: 2006 vol. 45 p. 657 - 667
DE PRAT-GAY G.; NADRA ALEJANDRO D.; CORRALES-IZQUIERDO FJ; ALONSO LEONARDO G.; FERREIRO DU; MOK YK
The folding mechanism of a dimeric beta-barrel domain
JOURNAL OF MOLECULAR BIOLOGY; Año: 2005 vol. 351 p. 672 - 682
MORELLI L; LLOVERA RE; ALONSO LEONARDO G; FRANGIONE B; DE PRAT-GAY G; GHISO J; CASTANO EM
Insulin-degrading enzyme degrades amyloid peptides associated with British and Danish familial dementia
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 2005 vol. 332 p. 808 - 816
ALONSO LEONARDO G.; GARCIA-ALAI MM; SMAL C; CENTENO JM; IACONO R; CASTANO E; GUALFETTI P; DE PRAT-GAY G
The HPV16 E7 viral oncoprotein self-assembles into defined spherical oligomers.Alonso LG, Garcia-Alai
BIOCHEMISTRY; Año: 2004 vol. 43 p. 3310 - 3317
DI PIETRO SM; CENTENO JM; CERUTTI ML; LODEIRO MF; FERREIRO DU; ALONSO LEONARDO G.; SCHWARZ FP; GOLDBAUM FA; DE PRAT-GAY G
Specific antibody-DNA interaction: a novel strategy for tight DNA recognition.
BIOCHEMISTRY; Año: 2003 vol. 42 p. 6218 - 6227
CARAMELO JJ; CASTRO OA; ALONSO LEONARDO G.; DE PRAT-GAY G; PARODI AJ
UDP-Glc:glycoprotein glucosyltransferase recognizes structured and solvent accessible hydrophobic patches in molten globule-like folding intermediates
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2003 vol. 100 p. 86 - 91
ALONSO LEONARDO G; GARCIA-ALAI MM; NADRA AD; LAPENA AN; ALMEIDA FL; GUALFETTI P; PRAT-GAY GD
High-risk (HPV16) human papillomavirus E7 oncoprotein is highly stable and extended, with conformational transitions that could explain its multiple cellular binding partners
BIOCHEMISTRY; Año: 2002 vol. 41 p. 10510 - 10518
FERREIRO DU; LIMA LM; NADRA AD; ALONSO LEONARDO G; GOLDBAUM FA; DE PRAT-GAY G
Distinctive cognate sequence discrimination, bound DNA conformation, and binding modes in the E2 C-terminal domains from prototype human and bovine papillomaviruses
BIOCHEMISTRY; Año: 2000 vol. 39 p. 14692 - 14701
MOK YK; ALONSO LEONARDO G; LIMA LM; BYCROFT M; DE PRAT-GAY G
Folding of a dimeric beta-barrel: residual structure in the urea denatured state of the human papillomavirus E2 DNA binding domain
PROTEIN SCIENCE; Año: 2000 vol. 9 p. 799 - 811
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