SOY BASED DIET INFLUENCES IN HEMATOLOGICAL MODIFICATIONS INDUCED BY CADMIUM INTOXICATION IN RATS

CIMINARI ME; ÁLVAREZ SM; BOLDRINI GG; MARTIN MOLINERO GD; SALINAS E; GÓMEZ NN

San Luis

Congreso; Reunión Anual de la Sociedad de Biología de Cuyo; 2019

Sociedad de Biologia de Cuyo

Cadmium (Cd) is a toxic metal and it is considered an important environmental contaminant. Furthermore, it is widely known that consumption of soy protein has beneficial health effects. We studied cadmium effects on hematological parameters under different diets in 4 lots of female Wistar rats: 2 lots received casein (Cas) and 2 lots received soybean flour (So) as protein sources. Within each group: 1 lot received regular water (control-Co) and the other 15ppm of Cd in drinking water for 60 days. Blood samples were collected in heparinized tubes and they were analyzed using a hemocytometer ADVIA 360 (SIEMENS) and an autoanalyzer A15 (BIOSYSTEMS). ANOVA test was used for statistical analysis. Red Blood Cells Count (RBC) decreased in SoCo vs. CasCo (p