IQUIMEFA 05518
INSTITUTO QUIMICA Y METABOLISMO DEL FARMACO
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
A N4-aryl substituted thiosemicarbazone down-modulates metastasis-related properties of triple negative 4T1 mouse mammary cancer cells
Autor/es:
A. SÓLIMO, M.C. SORAIRES SANTACRUZ, A.I. LOAIZA PEREZ, E. BAL DE KIER JOFF., L. FINKIELSZTEIN, M.A. CALLERO
Reunión:
Congreso; Reunión Conjunta de Sociedades de Biociencias; 2017
Resumen:
Previously, we found that T2, a N4-aryl substituted thiosemicarbazone, had cytotoxic activity on 4T1 mouse mammary tumor cells. Now we investigated the action of T2 on metastasis-related properties of 4T1 cells. Our results show that T2 inhibits some of the metastasis-related properties of 4T1 cells, placing this compound as a candidate for in vivo experiments to investigate its anti-metastasic potential against triple negative breast cancer
