INTECIN   20395
INSTITUTO DE TECNOLOGIAS Y CIENCIAS DE LA INGENIERIA "HILARIO FERNANDEZ LONG"
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Natural Hydroxyapatite Bioceramic-Collagen based Bone Composites Production.
Autor/es:
C.FERNADEZ; A. OZOLS; C. MARTINEZ ; J. FAIG; J. LOCS; L. CIMDIņA-BēRZIņA
Lugar:
Chengdu
Reunión:
Congreso; 9th World Biomaterials Congress; 2012
Institución organizadora:
Biomaterial Society
Resumen:
The collagen and calcium phosphate based composites
were synthesized with the aim to use them as bone substitutes. This combination
pretends to mimics the synergy of organic and inorganic phases during bone
genesis. The effort was focused in getting stiff composites, able to be moulded
in as dowels and plates that fit into alveolar defects and allow lifting sinus
ridge, situation barely satisfied by known commercial products. The organic
phase is mainly composed by collagen, extracted from bovine ligaments and
bones, by chemical digestion in bioreactor. The inorganic phase was composed by
ceramic particles obtained from chemically and thermally reprocessed fresh
bovine bone. The product was frizzed, dried in mild vacuum, and sterilizing
under per-acetic acid vapour. The mechanical performance is evaluated thought
flexural strength. Such strength could be attributed to the composite microstructure
of ceramic particles tapped and adhered to organic matrix, as it is observed by
electronic microscope. The process was able to manage by means of phase ratio
the porosity in the 50-90 % range. These features make easer the use of
composites as bone fillers, with strength higher than similar known composites.
The
moulding ability of these composites is adequate for producing clinically
useful pieces, which good mechanical performance