Genomic overview of Proteolytic Enzymes in Lactobacillus delbrueckii: Implications for Dairy Fermentation

ELEAN, M.; ALBARRACIN, L.; VILLENA, J.C.; SAAVEDRA, L.; HEBERT, E.M.

Congreso; XIII Argentine Congress of Bioinformatics andComputational Biology (XIII CAB2C) XIII International Conference of the IberoamericanSociety of Bioinformatics (XIII SoIBio) III Annual Meeting of the Ibero-American ArtificialIntelligence Network for Big BioDa; 2023

Lactobacillus delbrueckii is widely recognized as the primary starter culture in the dairy industryfor the elaboration of a variety of fermented dairy products, such as yogurts, fermented sour milks,mozzarella, and Swiss and Italian cheeses. This group of microorganisms has a limited capacity tosynthesize amino acids and is therefore dependent on the use of exogenous nitrogen sources foroptimal growth. As milk contains only small amounts of amino acids and short peptides,Lactobacillus depend on a complex proteolytic system to obtain essential amino acids from caseinsduring growth in this substrate. The cell envelope proteinase (CEP) stands as a pivotal enzyme,initiating the hydrolysis of casein. Strain-specific differences in proteolytic activity have beenobserved, prompting an investigation into potential disparities in CEPs.</div><div class="CodeMirror-scroll" tabindex="-1" draggable="true"><div class="CodeMirror-sizer" style="margin-left: 0px; min-width: 7px; margin-bottom: -17px; border-right-width: 33px; min-height: 28px; padding-right: 0px; padding-bottom: 0px;"><div style="position: relative; top: 0px;"><div class="CodeMirror-lines" role="presentation"><div style="position: relative; outline: none;" role="presentation"><div class="CodeMirror-measure" /><div class="CodeMirror-measure" /><div style="position: relative; z-index: 1;" /><div class="CodeMirror-cursors" style="visibility: hidden;"><div class="CodeMirror-cursor" style="left: 4px; top: 0px; height: 17px;" /></div><div class="CodeMirror-code" role="presentation"><pre class=" CodeMirror-line " role="presentation"><span role="presentation"><span>​</span></span></pre></div></div></div></div></div></div></div></div></div></body></html>