SACERDOTI, M; GROSS, LISSY ZF; RILEY, A; ZEHNDER, K; GHODE, A; KLINKE, S; ANAND, GS; PARIS, K; WINKEL, A; HERBRAND, AK; GODAGE, HY; COZIER, GE; SUESS, E; SCHULZE, JO; PASTOR-FLORES, DANIEL; BOLLINI, M; CAPPELLARI, MV; SVERGUN, DI; GRÄWERT, M; ARAMENDIA, PF; LEROUX, AE; POTTER, B; CAMACHO, CJ; BIONDI, RM

Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein

Science Signaling; Año: 2023 vol. 16

LEROUX, ALEJANDRO E.; BIONDI, RICARDO M.

The choreography of protein kinase PDK1 and its diverse substrate dance partners

BIOCHEMICAL JOURNAL; Año: 2023 vol. 480 p. 1503 - 1532

ALCOBER-BOQUET, LUCIA; ZANG, TABEA; PIETSCH, LARISSA; SUESS, EVELYN; HARTMANN, MARKUS; PROSCHAK, EWGENIJ; GROSS, LISSY Z. F.; SACERDOTI, MARIANA; ZEUZEM, STEFAN; ROGOV, VLADIMIR V.; LEROUX, ALEJANDRO E.; PIIPER, ALBRECHT; BIONDI, RICARDO M.

The PB1 and the ZZ domain of the autophagy receptor p62/SQSTM1 regulate the interaction of p62/SQSTM1 with the autophagosome protein LC3B

PROTEIN SCIENCE; Lugar: New York; Año: 2023 vol. 33

GROSS, LISSY Z.F.; SACERDOTI, MARIANA; PIIPER, ALBRECHT; ZEUZEM, STEFAN; LEROUX, ALEJANDRO E.; BIONDI, RICARDO M.

ACE2, the Receptor that Enables the Infection by SARS‐CoV‐2: Biochemistry, Structure, Allostery and Evaluation of the Potential Development of ACE2 Modulators

CHEMMEDCHEM; Año: 2020

LEROUX, ALEJANDRO E.; BIONDI, RICARDO M.

Renaissance of Allostery to Disrupt Protein Kinase Interactions

TRENDS IN BIOCHEMICAL SCIENCES; Año: 2020

CURRIER, RACHEL B.; ULRICH, KATHRIN; LEROUX, ALEJANDRO E.; DIRDJAJA, NATALIE; DEAMBROSI, MATÍAS; BONILLA, MARIANA; AHMED, YASAR LUQMAN; ADRIAN, LORENZ; ANTELMANN, HAIKE; JAKOB, URSULA; COMINI, MARCELO A.; KRAUTH-SIEGEL, R. LUISE

An essential thioredoxin-type protein of Trypanosoma brucei acts as redox-regulated mitochondrial chaperone

PLOS Pathogens; Año: 2019 vol. 15

GIORDANA, LUCILA; SOSA, MÁXIMO HERNÁN; LEROUX, ALEJANDRO E.; MENDOZA, ELKIN F. RODAS; PETRAY, PATRICIA; NOWICKI, CRISTINA

Molecular and functional characterization of two malic enzymes from Leishmania parasites

MOLECULAR AND BIOCHEMICAL PARASITOLOGY; Año: 2018 vol. 219 p. 67 - 76

LEROUX, ALEJANDRO E.; SCHULZE, JÖRG; BIONDI, RICARDO M.

AGC kinases, mechanisms of regulation ‎and innovative drug development

SEMINARS IN CANCER BIOLOGY; Año: 2018 vol. 48 p. 1 - 17

LEROUX, ALEJANDRO E.; KRAUTH-SIEGEL, R. LUISE

Thiol redox biology of trypanosomatids and potential targets for chemotherapy

MOLECULAR AND BIOCHEMICAL PARASITOLOGY; Lugar: Amsterdam; Año: 2016 vol. 206 p. 67 - 74

ACHCAR, F.; FADDA, A.; HAANSTRA, J.R.; KERKHOVEN, E.J.; KIM, D.H.; LEROUX, ALEJANDRO E.; PAPAMARKOU, T.; ROJAS, F.; BAKKER, B. M.; BARRETT, M.P.; CLAYTON, C.; GIROLAMI, M.; KRAUTH-SIEGEL, R. LUISE; MATTHEWS, K.R.; BREITLING, R.

The silicon trypanosome: a test case of iterative model extension in systems biology

ADVANCES IN MICROBIAL PHYSIOLOGY; Lugar: Amsterdam; Año: 2014 vol. 64 p. 115 - 143

LEROUX, ALEJANDRO E.; HAANSTRA, J. R.; BAKKER, B. M.; KRAUTH-SIEGEL, R. LUISE

Dissecting the Catalytic Mechanism of Trypanosoma brucei Trypanothione Synthetase by Kinetic Analysis and Computational Modelling

JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 2013 vol. 288 p. 2375 - 23764

STEFANIE ZIMMERMANN; MOUHSSIN OUFIR; ALEJANDRO LEROUX; R. LUISE KRAUTH-SIEGEL; KATJA BECKER; MARCEL KAISER; RETO BRUN; MATTHIAS HAMBURGER; MICHAEL ADAMS

Cynaropicrin targets the trypanothione redox system in Trypanosoma brucei

BIOORGANIC & MEDICINAL CHEMISTRY.; Lugar: Amsterdam; Año: 2013 vol. 21 p. 7202 - 7209

KRAUTH-SIEGEL, R. LUISE; LEROUX, ALEJANDRO E.

Low-Molecular-Mass Antioxidants in Parasites

ANTIOXIDANTS & REDOX SIGNALING; Lugar: New York; Año: 2012 vol. 17 p. 583 - 607

LEROUX, ALEJANDRO E.; MAUGERI, DANTE; CAZZULO, JUAN JOSÉ; NOWICKI, CRISTINA

Functional characterization of NADP-dependent isocitrate dehydrogenase isozymes from Trypanosoma cruzi

MOLECULAR AND BIOCHEMICAL PARASITOLOGY; Lugar: Amsterdam; Año: 2011 vol. 177 p. 61 - 64

LEROUX, ALEJANDRO E.; MAUGERI, DANTE; OPPERDOES, FREDERIC; CAZZULO, JUAN JOSÉ; NOWICKI CRISTINA

Comparative studies on the biochemical properties of the malic enzymes from Trypanosoma cruzi and Trypanosoma brucei

FEMS MICROBIOLOGY LETTERS; Año: 2010 vol. 314 p. 25 - 33

LEROUX, ALEJANDRO E.; FLEMING-CANEPA, X; ARANDA, A; MAUGERI, D; CAZZULO, JUAN JOSÉ; SÁNCHEZ, MARCO A.; NOWICKI, CRISTINA

Functional characterization and subcellular localization of the three malate dehydrogenase isozymes in Leishmania spp.

MOLECULAR AND BIOCHEMICAL PARASITOLOGY; Lugar: Amsterdam; Año: 2006 vol. 149 p. 74 - 85