Lactic Acid Bacteria as Cell Factories for the Generation of Bioactive Peptides

BROWN, L.; VERA PINGITORE, E.; MOZZI, F.; SAAVEDRA, L.; VILLEGAS, J.M.; HEBERT, E.M.

PROTEIN AND PEPTIDE LETTERS

BENTHAM SCIENCE PUBL LTD

Lugar: Oak Park; Año: 2017 vol. 24 p. 146 - 155

0929-8665

Thereis a growing interest in the incorporation of functional foods in the dailydiet to achieve health promotion and disease risk reduction. Numerous studieshave focused on the production of biologically active peptides asnutraceuticals and functional food ingredients due to their health benefits.These short peptides, displaying antihypertensive, antioxidant, mineralbinding, immunomodulatory and antimicrobial activities are hidden in a latentstate within the primary sequences of food proteins requiring enzymaticproteolysis for their release. While microbial fermentation is one of the majorand economically most convenient processes used to generate bioactive peptides,lactic acid bacteria (LAB) are widely used as starter cultures for theproduction of diverse fermented foods. This article reviews the current knowledgeon LAB as cell factories for the production of bioactive peptides from avariety ...