POLYPHENOLS CONTENT AND EVALUATION OF ANTICHEMOTACTIC, ANTIEDEMATOGENIC AND ANTIOXIDANT ACTIVITIES OF Rubus sp. CULTIVARS.

MARIA ROSANA RAMIREZ, MIRIAM ANDERS APEL, MARIA DO CARMO BASSOLS RASEIRA, JOSÊ ÂNGELO S. ZUANAZZI AND AMELIA TERESINHA HENRIQUES.

JOURNAL OF FOOD BIOCHEMISTRY

WILEY-BLACKWELL PUBLISHING, INC

Año: 2009 p. 1 - 17

0145-8884

<!-- /* Font Definitions */ @font-face {font-family:Calibri; mso-font-alt:"Century Gothic"; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-1610611985 1073750139 0 0 159 0;} /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-parent:""; margin-top:0cm; margin-right:0cm; margin-bottom:10.0pt; margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:Calibri; mso-fareast-font-family:Calibri; mso-bidi-font-family:"Times New Roman"; mso-ansi-language:PT-BR; mso-fareast-language:EN-US; mso-bidi-language:AR-SA;} @page Section1 {size:595.3pt 841.9pt; margin:70.85pt 3.0cm 70.85pt 3.0cm; mso-header-margin:35.4pt; mso-footer-margin:35.4pt; mso-paper-source:0;} div.Section1 {page:Section1;} --> Articulo acepto por la revista Journal of Food Biochemistry Manuscript ID JFBC-09-09-0285.   The purpose of this study was to compare the composition, antioxidant, antichemotactic and antiedematogenic properties of total extracts and anthocyanin-containing Rubus sp. extracts from selected cultivars. Rubus cultivars containing similar profile of anthocyanins, but greater levels of polyphenolics compounds increased antioxidant activity, and significantly enhanced antichemotactic and antiedematogenic properties. Cyanidin-3-glucoside isolated caused little or no anti-inflammatory effects in vitro/in vivo at same concentrations. These data suggest that polyphenols in Rubus extract act synergistically or additively in producing anti-inflammatory/antioxidant effects. These finding also provide essential information for the development of fruit-derived Rubus sp. as potential botanical drug products.