Assessment of effectiveness of oral supplementation of isolated fi ber of carrot on metabolic parameters in mature rats

RAMIREZ MR,; MANUALE D; YORI JC

Food Science and Human Wellness

Elsevier

Lugar: Amsterdam; Año: 2022

2213-4530

This present study was conducted to evaluate the metabolic effects of isolated fi ber of carrot supplementation in rats. Physicochemical properties of fi ber were determined. The groups were as follows: animals fed a standard diet, control group; high fi ber supplementation (70 mg); low fi ber supplementation (35 mg); for 12 weeks. Blood samples were collected at the time of sacrifi ce. The weights of heart, liver, kidneys and spleen of the experimental rats with respect to body weight were recorded. Commercial kits were used to determine serum glucose concentration, lipid profi le (cholesterol, HDL-cholesterol, triglycerides), and the two main aminotransferases glutamic-oxalacetic transaminase (GOT)/glutamate-pyruvate transaminase (GPT). A histopathological assay was performed on the heart, liver, and spleen tissues of animals. Supplementation with fi ber favors weight loss in female ((242.03 ± 23.73) g - (197.81 ± 10.45)) g; and male rats ((262.50 ± 32.21) g- (213.96 ± 12.56) g and induces a decrease in glucose levels in the supplemented animals. With the exception of total high-density lipoprotein cholesterol, the other lipid fractions decrease signifi cantly in rats supplemented. Fiber supplementation did not induce changes in the dissected organs of the supplemented animals. In conclusion supplementation of fi ber, improves glucose control, lower plasma lipid concentrations and reduced body weight in normal rats