INVESTIGADORES
CABEZUDO Ignacio
artículos
Título:
Two-Stage Amplification of Receptors Using a Multilevel Orthogonal/Simultaneous Dynamic Combinatorial Library
Autor/es:
ANDREA M. ESCALANTE; A. GASTÓN ORRILLO; IGNACIO CABEZUDO; RICARDO L. E. FURLAN
Revista:
ORGANIC LETTERS
Editorial:
AMER CHEMICAL SOC
Referencias:
Lugar: Washington; Año: 2012 p. 5816 - 5819
ISSN:
1523-7060
Resumen:
Sequential activation of different reversible exchange reactions in a dynamic combinatorial library allows directed exploration of the chemical space: initially a macrocyclic scaffold is selected by the template and finally side chain and conformational constrains are introduced into such a scaffold.
