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Deoxycytidine kinase (dCK) inhibition is synthetic lethal with BRCA2 deficiency

DRUG RESISTANCE UPDATES; Lugar: ESCOCIA; Año: 2023

MANSILLA, SABRINA FLORENCIA; BERTOLIN AGOSTINA; SOFIA VENERUS ARBILLA; CASTAÑO, BRYAN; TIYA JAHJAH; JENNY K. SINGH; SEBASTIÁN OMAR SIRI; MARIA VICTORIA CASTRO ; MARIA BELEN DE LA VEGA; ANNABEL QUINET ; WIESMÜLLER, LISA; VANESA GOTTIFREDI

Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability

Science Advances; Lugar: washington; Año: 2023

SIRI, SEBASTIÁN O.; MARTINO, JULIETA; CALZETTA, NICOLÁS L.; PAVIOLO, NATALIA S.; GARRO, CINTIA; PANSA, MARÍA F.; CARBAJOSA, SOFÍA; BROWN, AARON C.; BOCCO, JOSÉ L.; GLOGER, ISRAEL; DREWES, GERARD; MADAUSS, KEVIN P.; SORIA, GASTÓN; GOTTIFREDI, VANESA

Inhibitors of Rho kinases (ROCK) induce multiple mitotic defects and synthetic lethality in BRCA2-deficient cells

eLife; Año: 2023 vol. 12

SIRI, SEBASTIÁN OMAR; MARTINO, JULIETA; GOTTIFREDI, VANESA

Structural chromosome instability: Types, origins, consequences, and therapeutic opportunities

Cancers; Lugar: Basel; Año: 2021 vol. 13

MANSILLA, SABRINA FLORENCIA; DE LA VEGA, MARÍA BELÉN; CALZETTA, NICOLÁS LUIS; SIRI, SEBASTIÁN OMAR; GOTTIFREDI, VANESA

CDK-Independent and PCNA-Dependent Functions of p21 in DNA Replication

Genes; Lugar: Basel; Año: 2020 vol. 11

SIRI, SEBASTIAN O.; ROZÉS-SALVADOR, VICTORIA; DE LA VILLARMOIS, EMILCE ARTUR; GHERSI, MARISA S.; QUASSOLLO, GONZALO; PÉREZ, MARIELA F.; CONDE, CECILIA

Decrease of Rab11 prevents the correct dendritic arborization, synaptic plasticity and spatial memory formation

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH; Año: 2020

FEDERICO, MARÍA BELÉN; SIRI, SEBASTIÁN OMAR; CALZETTA, NICOLÁS LUIS; PAVIOLO, NATALIA SOLEDAD; DE LA VEGA, MARÍA BELÉN; MARTINO, JULIETA; CAMPANA, MARÍA CAROLINA; WIESMÜLLER, LISA; GOTTIFREDI, VANESA

Unscheduled MRE11 activity triggers cell death but not chromosome instability in polymerase eta-depleted cells subjected to UV irradiation

ONCOGENE; Año: 2020 vol. 39 p. 3952 - 3964

VICTORIA ROZÉS-SALVADOR; SIRI, SEBASTIÁN OMAR; MELINA M. MUSRI; CONDE, CECILIA

New Player in Endosomal Trafficking: Differential Roles of Smad Anchor for Receptor Activation (SARA) Protein

MOLECULAR AND CELLULAR BIOLOGY; Lugar: Washington; Año: 2018

ARIAS, CRISTINA ISABEL; SIRI, SEBASTIÁN OMAR; CONDE, CECILIA

Involvement of SARA in axon and dendrite growth

PLOS ONE; Año: 2015 vol. 10