MATIAS GARCIA FALLIT; MATIAS PIDRE; ASAD, ANTONELA SOFÍA; JORGE PEÑA AGUDELO; MARIANA VERA; NICOLA CANDIA, ALEJANDRO JAVIER; SOFIA SAGRIPANTI; MELANIE PEREZ KUPER; LESLIE C. AMORÓS MORALES; ABRIL MARCHESINI; NAZARENO GONZÁLEZ; CARLA CARUSO; VICTOR ROMANOWSKY; SEILICOVICH, ADRIANA; GUILLERMO A. VIDELA-RICHARDSON ; FLAVIA ZANETTI; CANDOLFI, MARIANELA

Evaluation of Baculoviruses as Gene Therapy Vectors for Brain Cancer

Viruses; Año: 2023

PEÑA AGUDELO, JORGE A.; PIDRE, MATÍAS L.; GARCIA FALLIT, MATIAS; PÉREZ KÜPER, MELANIE; ZUCCATO, CAMILA; NICOLA CANDIA, ALEJANDRO J.; MARCHESINI, ABRIL; VERA, MARIANA B.; DE SIMONE, EMILIO; GIAMPAOLI, CARLA; AMORÓS MORALES, LESLIE C.; GONZALEZ, NAZARENO; ROMANOWSKI, VÍCTOR; VIDELA-RICHARDSON, GUILLERMO A.; SEILICOVICH, ADRIANA; CANDOLFI, MARIANELA

Mitochondrial Peptide Humanin Facilitates Chemoresistance in Glioblastoma Cells

Cancers; Año: 2023 vol. 15

NICOLA CANDIA, ALEJANDRO J.; GARCIA FALLIT, MATÍAS; PEÑA AGUDELO, JORGE A.; PÉREZ KÜPER, MELANIE; GONZALEZ, NAZARENO; MORENO AYALA, MARIELA A.; DE SIMONE, EMILIO; GIAMPAOLI, CARLA; CASARES, NOELIA; SEILICOVICH, ADRIANA; LASARTE, JUAN JOSÉ; ZANETTI, FLAVIA A.; CANDOLFI, MARIANELA

Targeting FOXP3 Tumor-Intrinsic Effects Using Adenoviral Vectors in Experimental Breast Cancer

Viruses; Año: 2023 vol. 15

CARDAMA, GEORGINA A.; MAGGIO, J.; LUCAS VALDEZ CAPUCCINO; NAZARENO GONZÁLEZ; DANIEL F. ALONSO

Preclinical Efficacy and Toxicology Evaluation of RAC1 Inhibitor 1A-116 in Human Glioblastoma Models

Cancers; Año: 2022

ANDREA FRANSON; BRANDON L MCCLELLAN ; MARIA LUISA VARELA; COMBA, ANDREA; MOHAMMAD FAISAL SYED; KAUSHIK BANERJEE; ZIWEN ZHU; NAZARENO GONZÁLEZ; CANDOLFI, MARIANELA; PEDRO LOWENSTEIN; CASTRO, MARIA

Development of immunotherapy for high-grade gliomas: Overcoming the immunosuppressive tumor microenvironment

Frontiers in Medicine; Año: 2022

ROSSO, DAVID; GONZALEZ, NAZARENO; JANCIC, CAROLINA

Glioblastoma cells potentiate the induction of the Th1-like profile in phosphoantigen-stimulated γδ T lymphocytes

JOURNAL OF NEURO-ONCOLOGY.; Lugar: Berlin; Año: 2021

GONZÁLEZ, NAZARENO; CARDAMA, GEORGINA A.; CHINESTRAD, PATRICIO; ROBLES-VALERO, JAVIER; RODRÍGUEZ-FDEZ, SONIA; LORENZO-MARTÍN, L. FRANCISCO; BUSTELO, XOSÉ R.; LORENZANO MENNA, PABLO; GOMEZ, DANIEL E.

Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity

Frontiers in Cell and Developmental Biology; Año: 2020 vol. 8

LORENZO-MARTÍN, L. FRANCISCO; FERNÁNDEZ-PAREJO, NATALIA; MENACHO-MÁRQUEZ, MAURICIO; RODRÍGUEZ-FDEZ, SONIA; ROBLES-VALERO, JAVIER; ZUMALAVE, SONIA; FABBIANO, SALVATORE; PASCUAL, GLORIA; GARCÍA-PEDRERO, JUANA M.; ABAD, ANTONIO; GARCÍA-MACÍAS, MARÍA C.; GONZÁLEZ, NAZARENO; LORENZANO-MENNA, PABLO; PAVÓN, MIGUEL A.; GONZÁLEZ-SARMIENTO, ROGELIO; SEGRELLES, CARMEN; PARAMIO, JESÚS M.; TUBÍO, JOSÉ M. C.; RODRIGO, JUAN P.; BENITAH, SALVADOR A.; CUADRADO, MYRIAM; BUSTELO, XOSÉ R.

VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma

NATURE COMMUNICATIONS; Año: 2020 vol. 11

ASAD, ANTONELA S; NICOLA CANDIA, ALEJANDRO J; GONZALEZ, NAZARENO; ZUCCATO, CAMILA F; SEILICOVICH, ADRIANA; CANDOLFI, MARIANELA

The role of the prolactin receptor pathway in the pathogenesis of glioblastoma: what do we know so far?

EXPERT OPINION ON THERAPEUTIC TARGETS; Año: 2020

GONZÁLEZ, NAZARENO; CARDAMA, GEORGINA A.; CHINESTRAD, PATRICIO; ROBLES-VALERO, JAVIER; RODRÍGUEZ-FDEZ, SONIA; LORENZO-MARTÍN, L. FRANCISCO; BUSTELO, XOSÉ R.; LORENZANO MENNA, PABLO; GOMEZ, DANIEL E.

Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity

Frontiers in Cell and Developmental Biology; Año: 2020 vol. 8

GONZÁLEZ, NAZARENO; ARCOS LÓPEZ, TRINIDAD; KÖNIG, ANNEKATRIN; QUINTANAR, LILIANA; MENACHO MÁRQUEZ, MAURICIO; OUTEIRO, TIAGO F.; FERNÁNDEZ, CLAUDIO O.

Effects of alpha‐synuclein post‐translational modifications on metal binding

JOURNAL OF NEUROCHEMISTRY; Año: 2019 vol. 150 p. 507 - 521

ASAD, ANTONELA SOFÍA; NICOLA CANDIA, ALEJANDRO JAVIER; GONZALEZ, NAZARENO; ZUCCATO, CAMILA FLORENCIA; ABT, ARACELI; ORRILLO, SANTIAGO JORDI; LASTRA, YAEL; DE SIMONE, EMILIO; BOUTILLON, FLORENCE; GOFFIN, VINCENT; SEILICOVICH, ADRIANA; PISERA, DANIEL ALBERTO; FERRARIS, MARÍA JIMENA; CANDOLFI, MARIANELA

Prolactin and its receptor as therapeutic targets in glioblastoma multiforme

Scientific Reports; Año: 2019 vol. 9

DELGADO OCAÑA, SUSANA; GONZALEZ, NAZARENO; FERNÁNDEZ, CLAUDIO O.

Abstracts of the 2018 Meeting of ArgentineSociety for Research in Neurosciences

ASN Neuro; Año: 2019 vol. 11

GONZÁLEZ, NAZARENO; GENTILE, IÑAKI; GARRO, HUGO A.; DELGADO-OCAÑA, SUSANA; RAMUNNO, CARLA F.; BURATTI, FIAMMA A.; GRIESINGER, CHRISTIAN; FERNÁNDEZ, CLAUDIO O.

Metal coordination and peripheral substitution modulate the activity of cyclic tetrapyrroles on αS aggregation: a structural and cell-based study

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY; Año: 2019 vol. 24 p. 1269 - 1278

DELGADO OCAÑA, SUSANA; GONZALEZ, NAZARENO; FERNÁNDEZ, CLAUDIO O.

Abstracts of the 2018 Meeting of ArgentineSociety for Research in Neurosciences

ASN Neuro; Año: 2019 vol. 11

GONZÁLEZ, NAZARENO; GENTILE, IÑAKI; GARRO, HUGO A.; DELGADO-OCAÑA, SUSANA; RAMUNNO, CARLA F.; BURATTI, FIAMMA A.; GRIESINGER, CHRISTIAN; FERNÁNDEZ, CLAUDIO O.

Metal coordination and peripheral substitution modulate the activity of cyclic tetrapyrroles on αS aggregation: a structural and cell-based study

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY; Año: 2019 vol. 24 p. 1269 - 1278

GONZÁLEZ, NAZARENO; ARCOS LÓPEZ, TRINIDAD; KÖNIG, ANNEKATRIN; QUINTANAR, LILIANA; MENACHO MÁRQUEZ, MAURICIO; OUTEIRO, TIAGO F.; FERNÁNDEZ, CLAUDIO O.

Effects of alpha‐synuclein post‐translational modifications on metal binding

JOURNAL OF NEUROCHEMISTRY; Año: 2019 vol. 150 p. 507 - 521

ASAD, ANTONELA SOFÍA; NICOLA CANDIA, ALEJANDRO JAVIER; GONZALEZ, NAZARENO; ZUCCATO, CAMILA FLORENCIA; ABT, ARACELI; ORRILLO, SANTIAGO JORDI; LASTRA, YAEL; DE SIMONE, EMILIO; BOUTILLON, FLORENCE; GOFFIN, VINCENT; SEILICOVICH, ADRIANA; PISERA, DANIEL ALBERTO; FERRARIS, MARÍA JIMENA; CANDOLFI, MARIANELA

Prolactin and its receptor as therapeutic targets in glioblastoma multiforme

Scientific Reports; Año: 2019 vol. 9

GENTILE, IÑAKI; GARRO, HUGO A.; DELGADO OCAÑA, SUSANA; GONZALEZ, NAZARENO; STROHÄKER, TIMO; SCHIBICH, DANIELA; QUINTANAR, LILIANA; SAMBROTTA, LUIS; ZWECKSTETTER, MARKUS; GRIESINGER, CHRISTIAN; MENACHO MÁRQUEZ, MAURICIO; FERNÁNDEZ, CLAUDIO O.

Interaction of Cu (I) with the Met-X3-Met motif of alpha-synuclein: binding ligands, affinity and structural features

METALLOMICS; Lugar: CAMBRIDGE; Año: 2018 vol. 10 p. 1383 - 1389

CARDAMA, G.A.; ALONSO, D.F.; GONZALEZ, N.; MAGGIO, J.; GOMEZ, D.E.; ROLFO, C.; MENNA, P.L.

Relevance of small GTPase Rac1 pathway in drug and radio-resistance mechanisms: Opportunities in cancer therapeutics

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY; Año: 2018 vol. 124 p. 29 - 36

CARDAMA, G.A.; ALONSO, D.F.; GONZALEZ, N.; MAGGIO, J.; GOMEZ, D.E.; ROLFO, C.; MENNA, P.L.

Relevance of small GTPase Rac1 pathway in drug and radio-resistance mechanisms: Opportunities in cancer therapeutics

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY; Año: 2018 vol. 124 p. 29 - 36

GENTILE, IÑAKI; GARRO, HUGO A.; DELGADO OCAÑA, SUSANA; GONZALEZ, NAZARENO; STROHÄKER, TIMO; SCHIBICH, DANIELA; QUINTANAR, LILIANA; SAMBROTTA, LUIS; ZWECKSTETTER, MARKUS; GRIESINGER, CHRISTIAN; MENACHO MÁRQUEZ, MAURICIO; FERNÁNDEZ, CLAUDIO O.

Interaction of Cu( i ) with the Met-X 3 -Met motif of alpha-synuclein: binding ligands, affinity and structural features

METALLOMICS; Lugar: CAMBRIDGE; Año: 2018 vol. 10 p. 1383 - 1389

CARDAMA, G.; GONZALEZ, N.; MAGGIO, J.; MENNA, P.; GOMEZ, D.

Rho GTPases as therapeutic targets in cancer (Review)

INTERNATIONAL JOURNAL OF ONCOLOGY; Año: 2017

NAZARENO GONZÁLEZ; GEORGINA A. CARDAMA; MARIA J. COMIN; VALERIA I. SEGATORI; MARINA PIFANO; DANIEL F. ALONSO; DANIEL E. GOMEZ; PABLO LORENZANO MENNA

Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells.

CELLULAR SIGNALLING; Lugar: Amsterdam; Año: 2017 vol. 30 p. 154 - 161

MAIA CABRERA; EMILIANA ECHEVERRIA; FEDERICO REMES LENICOV; GEORGINA CARDAMA; NAZARENO GONZALEZ; CARLOS DAVIO; NATALIA FERNANDEZ; PABLO LORENZANO MENNA

Pharmacological Rac1 inhibitors with selective apoptotic activity in human acute leukemic cell lines

Oncotarget; Año: 2017

PIFANO, MARINA; GARONA, JUAN; CAPOBIANCO, CARLA S.; GONZALEZ, NAZARENO; ALONSO, DANIEL F.; RIPOLL, GISELLE V.

Peptide Agonists of Vasopressin V2 Receptor Reduce Expression of Neuroendocrine Markers and Tumor Growth in Human Lung and Prostate Tumor Cells

Frontiers in Oncology; Año: 2017 vol. 7

CARDAMA, G.; GONZALEZ, N.; MAGGIO, J.; MENNA, P.; GOMEZ, D.

Rho GTPases as therapeutic targets in cancer (Review)

INTERNATIONAL JOURNAL OF ONCOLOGY; Año: 2017

PIFANO, MARINA; GARONA, JUAN; CAPOBIANCO, CARLA S.; GONZALEZ, NAZARENO; ALONSO, DANIEL F.; RIPOLL, GISELLE V.

Peptide Agonists of Vasopressin V2 Receptor Reduce Expression of Neuroendocrine Markers and Tumor Growth in Human Lung and Prostate Tumor Cells

Frontiers in Oncology; Año: 2017 vol. 7

MAIA CABRERA; EMILIANA ECHEVERRIA; FEDERICO REMES LENICOV; GEORGINA CARDAMA; NAZARENO GONZALEZ; CARLOS DAVIO; NATALIA FERNANDEZ; PABLO LORENZANO MENNA

Pharmacological Rac1 inhibitors with selective apoptotic activity in human acute leukemic cell lines

Oncotarget; Año: 2017

NAZARENO GONZÁLEZ; GEORGINA A. CARDAMA; MARIA J. COMIN; VALERIA I. SEGATORI; MARINA PIFANO; DANIEL F. ALONSO; DANIEL E. GOMEZ; PABLO LORENZANO MENNA

Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells.

CELLULAR SIGNALLING; Lugar: Amsterdam; Año: 2017 vol. 30 p. 154 - 161

GEORGINA A. CARDAMA; MARIA J. COMIN; LEANDRO HORNOS; NAZARENO GONZÁLEZ; LUCAS DEFELIPE; ADRIAN G. TURJANSKI; DANIEL F. ALONSO; DANIEL E. GOMEZ; PABLO LORENZANO MENNA

Preclinical development of novel Rac1-GEF signaling inhibitors using a rational design approach in highly aggressive breast cancer cell lines.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY; Año: 2014 p. 840 - 851

GEORGINA A. CARDAMA; MARIA J. COMIN; LEANDRO HORNOS; NAZARENO GONZÁLEZ; LUCAS DEFELIPE; ADRIAN G. TURJANSKI; DANIEL F. ALONSO; DANIEL E. GOMEZ; PABLO LORENZANO MENNA

Preclinical development of novel Rac1-GEF signaling inhibitors using a rational design approach in highly aggressive breast cancer cell lines.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY; Año: 2014 p. 840 - 851

GEORGINA A. CARDAMA; NAZARENO GONZÁLEZ; GANDOLFI-DONADÍO L; MARIA J. COMIN; DANIEL F. ALONSO; PABLO LORENZANO MENNA; DANIEL E. GOMEZ

Proapoptotic and antiinvasive activity of Rac1 small molecule inhibitors on malignant glioma cells

OncoTargets and Therapy; Año: 2014 vol. 7 p. 2021 - 2033