SARAPURA MARTÍNEZ, VALERIA JUDITH; BUONINCONTRO BRENDA; CASSARINO CHIARA; BERNATOWIEZ, JULIANA; COLADO ANA; CORDINI, GREGORIO; CUSTIDIANO, MARÍA DEL ROSARIO; PAVLOVSKY, MIGUEL; BEZARES FERNANDO; FABALE NICOLAS; VERMEULEN MONICA; BORGE MERCEDES; GIORDANO MIRTA; GAMBERALE ROMINA

Venetoclax resistance induced by activated T cells can be counteracted by sphingosine kinase inhibitors in chronic lymphocytic leukemia

Frontiers in Oncology; Año: 2023

ELÍAS, ESTEBAN E; SARAPURA MARTÍNEZ, VALERIA JUDITH; AMONDARAIN, MIKELE; COLADO, ANA; CORDINI, GREGORIO; BEZARES FERNANDO RAIMUNDO; FERNANDEZ GRECCO, HORACIO; CUSTIDIANO, MARÍA DEL ROSARIO; AVALOS SANCHEZ JULIO; GARATE, GONZALO MARTÍN; PAVLOLVSY, MIGUEL; BORGE, MERCEDES; GIORDANO, MIRTA; GAMBERALE, ROMINA

Venetoclax-resistant CLL cells show a highly activated and proliferative phenotype

CANCER IMMUNOLOGY IMMUNOTHERAPY; Lugar: Berlin; Año: 2022 vol. 71 p. 979 - 987

ERRA, LORENZO; URIARTE, IGNACIO; COLADO, ANA; PAOLINI, MARÍA VIRGINIA; SEMINARIO, GISELA; FERNÁNDEZ, JULIETA BELÉN; TAU, LORENA; BERNATOWIEZ, JULIANA; MOREIRA, ILEANA; VISHNOPOLSKA, SEBASTIÁN; RUMBO, MARTÍN; CASSARINO, CHIARA; VIJODITZ, GUSTAVO; LÓPEZ, ANA LAURA; CURCIARELLO, RENATA; RODRÍGUEZ, DIEGO; RIZZO, GASTÓN; FERREYRA, MALENA; FERREYRA MUFARREGUE, LEILA ROMINA; BADANO, MARÍA NOEL; PÉREZ MILLÁN, MARÍA INÉS; QUIROGA, MARÍA FLORENCIA; BARÉ, PATRICIA; IBAÑEZ, ITATÍ; POZNER, ROBERTO; BORGE, MERCEDES; DOCENA, GUILLERMO; BEZRODNIK, LILIANA; ALMEJUN, MARÍA BELÉN

COVID-19 Vaccination Responses with Different Vaccine Platforms in Patients with Inborn Errors of Immunity

JOURNAL OF CLINICAL IMMUNOLOGY; Año: 2022

COLADO, ANA; ELÍAS, ESTEBAN ENRIQUE; SARAPURA MARTÍNEZ, VALERIA JUDITH; CORDINI, GREGORIO; MORANDE, PABLO; BEZARES, FERNANDO; GIORDANO, MIRTA; GAMBERALE, ROMINA; BORGE, MERCEDES

Immunomodulatory effects of different intravenous immunoglobulin preparations in chronic lymphocytic leukemia

Scientific Reports; Año: 2021 vol. 11

VEREERTBRUGGHEN, ALEXIA; COLADO, ANA; GARGIULO, ERNESTO; BEZARES, RAIMUNDO FERNANDO; FERNÁNDEZ GRECCO, HORACIO; CORDINI, GREGORIO; CUSTIDIANO, MARIA DEL ROSARIO; FRANÇOIS, JEAN-HUGUES; BERCHEM, GUY; BORGE, MERCEDES; PAGGETTI, JEROME; MOUSSAY, ETIENNE; GAMBERALE, ROMINA; GIORDANO, MIRTA; MORANDE, PABLO ELÍAS

In Vitro Sensitivity to Venetoclax and Microenvironment Protection in Hairy Cell Leukemia

Frontiers in Oncology; Año: 2021 vol. 11

COLADO, ANA; MARÍN FRANCO, JOSÉ L.; ELÍAS, ESTEBAN E.; AMONDARAIN, MIKELE; VERGARA RUBIO, MARICEF; SARAPURA MARTÍNEZ, VALERIA; CORDINI, GREGORIO; FUENTES, FEDERICO; BALBOA, LUCIANA; FERNANDEZ GRECCO, HORACIO; PAVLOLVSY, MIGUEL; BEZARES, FERNANDO; MORANDE, PABLO; GIORDANO, MIRTA; GAMBERALE, ROMINA; BORGE, MERCEDES

Second generation BTK inhibitors impair the anti‐fungal response of macrophages and neutrophils

AMERICAN JOURNAL OF HEMATOLOGY; Lugar: New York; Año: 2020

RISNIK, DENISE; COLADO, ANA; PODAZA, ENRIQUE; ALMEJÚN, MARÍA BELÉN; ELÍAS, ESTEBAN ENRIQUE; BEZARES, RAIMUNDO FERNANDO; FERNÁNDEZ-GRECCO, HORACIO; SEIJA, NOÉ; OPPEZZO, PABLO; BORGE, MERCEDES; GAMBERALE, ROMINA; GIORDANO, MIRTA

Immunoregulatory effects of Lurbinectedin in chronic lymphocytic leukemia

CANCER IMMUNOLOGY IMMUNOTHERAPY; Año: 2020 vol. 69 p. 813 - 824

RISNIK, DENISE; ELÍAS, ESTEBAN E.; KEITELMAN, IRENE; COLADO, ANA; PODAZA, ENRIQUE; CORDINI, GREGORIO; VERGARA RUBIO, MARICEF; FERNÁNDEZ GRECCO, HORACIO; BEZARES, RAIMUNDO FERNANDO; BORGE, MERCEDES; TREVANI, ANALÍA; GIORDANO, MIRTA; JANCIC, CAROLINA; GAMBERALE, ROMINA

The effect of ibrutinib on neutrophil and γδ T cell functions

LEUKEMIA AND LYMPHOMA; Año: 2020 p. 1 - 10

PODAZA, ENRIQUE; PALACIOS, FLORENCIA; CROCI, DIEGO O; RISNIK, DENISE; YAN, XIAO J; ALMEJÚN, MARÍA BELÉN; COLADO, ANA; ELÍAS, ESTEBAN E; BORGE, MERCEDES; MORANDE, PABLO E; BEZARES, RAIMUNDO; FERNÁNDEZ-GRECCO, HORACIO; RABINOVICH, GABRIEL A; GAMBERALE, ROMINA; CHIORAZZI, NICHOLAS; GIORDANO, MIRTA

Expression and function of cathelicidin hCAP18/LL-37 in chronic lymphocytic leukemia

HAEMATOLOGICA; Año: 2020

GORI, SOLEDAD; SOCZEWSKI, ELIZABETH; FERNÁNDEZ, LAURA; GRASSO, ESTEBAN; GALLINO, LUCILA; MERECH, FATIMA; COLADO, ANA; BORGE, MERCEDES; PÉREZ LEIRÓS, CLAUDIA; SALAMONE, GABRIELA; RAMHORST, ROSANNA

Decidualization Process Induces Maternal Monocytes to Tolerogenic IL-10-Producing Dendritic Cells (DC-10)

Frontiers in Immunology; Lugar: London; Año: 2020 vol. 11

PODAZA, ENRIQUE; RISNIK, DENISE; COLADO, ANA; ELÍAS, ESTEBAN; ALMEJÚN, MARÍA BELÉN; FERNANDEZ GRECCO, HORACIO; BEZARES, RAIMUNDO FERNANDO; BORGE, MERCEDES; GAMBERALE, ROMINA; GIORDANO, MIRTA

Chronic lymphocytic leukemia cells increase neutrophils survival and promote their differentiation into CD16 high CD62L dim immunosuppressive subset

INTERNATIONAL JOURNAL OF CANCER. JOURNAL INTERNATIONAL DU CANCER.; Año: 2019 vol. 144 p. 1128 - 1134

COLADO, ANA; GENOULA, MELANIE; COUGOULE, CÉLINE; MARÍN FRANCO, JOSÉ L.; ALMEJÚN, MARÍA B.; RISNIK, DENISE; KVIATCOVSKY, DENISE; PODAZA, ENRIQUE; ELÍAS, ESTEBAN E.; FUENTES, FEDERICO; MARIDONNEAU-PARINI, ISABELLE; BEZARES, FERNANDO R.; FERNANDEZ GRECCO, HORACIO; CABREJO, MARÍA; JANCIC, CAROLINA; SASIAIN, MARÍA DEL CARMEN; GIORDANO, MIRTA; GAMBERALE, ROMINA; BALBOA, LUCIANA; BORGE, MERCEDES

Effect of the BTK inhibitor ibrutinib on macrophage- and γδ T cell-mediated response against Mycobacterium tuberculosis

Blood Cancer Journal; Año: 2018 vol. 8

ELÍAS, ESTEBAN ENRIQUE; ALMEJÚN, MARÍA BELÉN; COLADO, ANA; CORDINI, GREGORIO; VERGARA-RUBIO, MARICEF; PODAZA, ENRIQUE; RISNIK, DENISE; CABREJO, MARÍA; FERNÁNDEZ-GRECCO, HORACIO; BEZARES, RAIMUNDO FERNANDO; CUSTIDIANO, MARÍA DEL ROSARIO; SÁNCHEZ-ÁVALOS, JULIO CÉSAR; VICENTE, ÁNGELES; GARATE, GONZALO MARTÍN; BORGE, MERCEDES; GIORDANO, MIRTA; GAMBERALE, ROMINA

Autologous T cell activation fosters ABT-199 resistance in chronic lymphocytic leukemia: rationale for a combined therapy with SYK inhibitors and anti-CD20 MoAbs.

HAEMATOLOGICA; Año: 2018

PODAZA ENRIQUE; FLORENCIA SABBIONE; RISNIK DENISE; BORGE MERCEDES; ALMEJÚN MARÍA BELÉN; COLADO ANA; FERNANDEZ GRECCO HORACIO; CABREJO MARÍA; BEZARES FERNANDO RAIMUNDO; TREVANI ANALÍA; GAMBERALE ROMINA; GIORDANO MIRTA

Neutrophils from chronic lymphocytic leukemia patients exhibit an increased capacity to release extracellular traps (NETs).

CANCER IMMUNOLOGY IMMUNOTHERAPY; Lugar: Berlin; Año: 2017

COLADO ANA; ALMEJÚN MARÍA BELÉN; PODAZA ENRIQUE; RISNIK DENISE; STANGANELLI CARMEN; ELÍAS ESTEBAN; DOS SANTOS PATRICIA; SLAVUTSKY IRMA; FERNANDEZ GRECCO HORACIO; CABREJO MARÍA; BEZARES FERNANDO RAIMUNDO; GIORDANO MIRTA; GAMBERALE ROMINA; BORGE MERCEDES

The kinase inhibitors R406 and GS-9973 impair T cell functions and macrophage-mediated anti-tumor activity of rituximab in chronic lymphocytic leukemia patients.

CANCER IMMUNOLOGY IMMUNOTHERAPY; Lugar: Berlin; Año: 2017 vol. 66 p. 461 - 473

ALMEJÚN, MARÍA BELÉN; BORGE, MERCEDES; COLADO, ANA; ELÍAS, ESTEBAN ENRIQUE; PODAZA, ENRIQUE; RISNIK, DENISE; DE BRASI, CARLOS DANIEL; STANGANELLI, CARMEN; SLAVUTSKY, IRMA; CABREJO, MARÍA; FERNÁNDEZ-GRECCO, HORACIO; BEZARES, RAIMUNDO FERNANDO; CRANCO, SANTIAGO; BURGOS, RUBÉN ÁNGEL; SÁNCHEZ-ÁVALOS, JULIO CÉSAR; OPPEZZO, PABLO; GIORDANO, MIRTA; GAMBERALE, ROMINA

Sphingosine kinase 1 participates in the activation, proliferation and survival of chronic lymphocytic leukemia cells.

HAEMATOLOGICA; Año: 2017

RISNIK, DENISE; PODAZA, ENRIQUE; ALMEJÚN, MARÍA B.; COLADO, ANA; ELÍAS, ESTEBAN E.; BEZARES, RAIMUNDO F.; FERNÁNDEZ-GRECCO, HORACIO; CRANCO, SANTIAGO; SÁNCHEZ-ÁVALOS, JULIO C.; BORGE, MERCEDES; GAMBERALE, ROMINA; GIORDANO, MIRTA

Revisiting the role of interleukin-8 in chronic lymphocytic leukemia

Scientific Reports; Año: 2017 vol. 7

ALMEJUN, MARÍA BELÉN; BORGE, MERCEDES

Somatic Hypermutation Defects in Common Variable Immune Deficiency

CURRENT ALLERGY AND ASTHMA REPORTS; Año: 2017 vol. 17

BORGE MERCEDES; MARÍA VICTORIA DELPINO; PODAZA ENRIQUE; STANGANELLI CARMEN; PALAU-NAGORE V; ROISMAN ALEJANDRO; SLAVUTSKY IRMA; PALACIOS MARÍA FERNANDA; LEDESMA IGNACIO; ARRA A; DIAZ A; GIORDANO MIRTA; GAMBERALE ROMINA; BEZARES FERNANDO RAIMUNDO

Soluble RANKL production by leukemic cells in a case of chronic lymphocytic leukemia with bone destruction

LEUKEMIA AND LYMPHOMA; Lugar: Londres; Año: 2016 vol. 25 p. 1 - 4

MORANDE PABLO ELIAS; BORGE MERCEDES; ABREU CECILIA; GALLETTI JEREMÍAS; ZANETTI SAMANTA; NANNINI PAULA ROMINA; BEZARES FERNANDO RAIMUNDO; DIGHIERO GUILLERMO; OPPEZZO PABLO; GAMBERALE ROMINA; GIORDANO MIRTA

Surface localization of high-mobility group nucleosome-binding protein 2 (HMGN2) on leukemic B cells from chronic lymphocytic leukemia patients is related to secondary autoimmune hemolytic anemi

LEUKEMIA AND LYMPHOMA; Lugar: Londres; Año: 2015

BORGE MERCEDES; ALMEJÚN MARÍA BELÉN; PODAZA ENRIQUE; COLADO ANA; CABREJO MARÍA; FERNANDEZ GRECCO HORACIO; BEZARES FERNANDO RAIMUNDO; GIORDANO MIRTA; GAMBERALE ROMINA

Ibrutinib impairs the phagocytosis of rituximab-coated leukemic cells from chronic lymphocytic leukemia patients by human macrophages.

HAEMATOLOGICA; Año: 2015

BORGE MERCEDES; REMES LENICOV FEDERICO; NANNINI PAULA ROMINA; MERCEDES DE LOS RIOS ALICANDU; PODAZA ENRIQUE; CABREJO MARÍA; FERNANDEZ GRECCO HORACIO; BEZARES FERNANDO RAIMUNDO; MORANDE PABLO ELIAS; OPPEZZO PABLO; GIORDANO MIRTA; GAMBERALE ROMINA

The Expression of Sphingosine-1 Phosphate Receptor-1 in Chronic Lymphocytic Leukemia Cells Is Impaired by Tumor Microenvironmental Signals and Enhanced by Piceatannol and R406.

JOURNAL OF IMMUNOLOGY; Lugar: Bethesda MD; Año: 2014 vol. 193 p. 3165 - 3174

CROCI DIEGO; MORANDE PABLO; DERGAN-DYLON S; BORGE MERCEDES; TOSCANO MARTA; STUPIRSKI JC; BEZARES FERNANDO RAIMUNDO; AVALOS SANCHEZ JULIO; NARBAITZ M; GAMBERALE ROMINA; RABINOVICH GABRIEL; GIORDANO MIRTA

Nurse-like cells control the activity of chronic lymphocytic leukemia B cells via galectin-1

LEUKEMIA; Lugar: Londres; Año: 2013 p. 1413 - 1416

ABREU CECILIA; MORENO PILAR; FLORENCIA PALACIOS; BORGE MERCEDES; MORANDE PABLO; LANDONI ANA INES; GABUS R; DIGHIERO GUILLERMO; GIORDANO MIRTA; GAMBERALE ROMINA; OPPEZZO PABLO

Methylation status regulates LPL expression in Chronic Lymphocytic Leukemia

LEUKEMIA AND LYMPHOMA; Lugar: Londres; Año: 2013 p. 1 - 2

BORGE MERCEDES; NANNINI PAULA ROMINA; MORANDE PABLO ELIAS; JANCIC CAROLINA; BISTMANS ALICIA; BEZARES FERNANDO RAIMUNDO; GIORDANO MIRTA; GAMBERALE ROMINA

CXCL12 is a costimulator for CD4+ T cell activation and proliferation in Chronic Lymphocytic Leukemia patients

CANCER IMMUNOLOGY IMMUNOTHERAPY; Lugar: Berlin; Año: 2013 p. 113 - 124

MORENO PILAR; ABREU CECILIA; BORGE MERCEDES; MORANDE PABLO ELIAS; PEGAZZANO MARIANA; FLORENCIA PALACIOS; BIANCHI SERGIO; LANDONI ANA INES; AGRELO RUBEN; GIORDANO MIRTA; DIGHIERO GUILLERMO; GAMBERALE ROMINA; OPPEZZO PABLO

Lipoprotein lipase expression in unmutated CLL patients is the consequence of a demethylation process induced by the microenvironment

LEUKEMIA; Lugar: Londres; Año: 2013 p. 1 - 4

MORANDE PABLO; ZANETTI SAMANTA; BORGE MERCEDES; NANNINI PAULA ROMINA; JANCIC CAROLINA; BEZARES FERNANDO RAIMUNDO; BISTMANS ALICIA; GONZÁLEZ MIGUEL; RODRIGUEZ ANDREA; GALMARINI CARLOS ; GAMBERALE ROMINA; GIORDANO MIRTA

The cytotoxic activity of Aplidin in chronic lymphocytic leukemia (CLL) is mediated by a direct effect on leukemic cells and an indirect effect on monocyte-derived cells.

INVESTIGATIONAL NEW DRUGS; Lugar: Berlin; Año: 2012 p. 1 - 11

NANNINI PAULA ROMINA; BORGE MERCEDES; MIKOLAITIS VANESA CARLA; ABREU CECILIA; MORANDE PABLO ELIAS; ZANETTI SAMANTA; OPPEZZO PABLO; PALACIOS FERNANDA; LEDESMA IGNACIO; BEZARES FERNANDO RAIMUNDO; GIORDANO MIRTA; GAMBERALE ROMINA

CCR4 expression in a case of cutaneous Richter's transformation of chronic lymphocytic leukemia (CLL) to diffuse large B-cell lymphoma (DLBCL) and in CLL patients with no skin manifestations.

EUROPEAN JOURNAL OF HAEMATOLOGY; Lugar: Londres; Año: 2011 vol. 87 p. 80 - 86

BORGE MERCEDES; NANNINI PAULA ROMINA; GALLETTI JEREMÍAS; MORANDE PABLO; SÁNCHEZ ÁVALOS JULIO; BEZARES FERNANDO RAIMUNDO; GIORDANO MIRTA; GAMBERALE ROMINA

CXCL12-induced chemotaxis is impaired in T cells from patients with ZAP-70-negative chronic lymphocytic leukemia

HAEMATOLOGICA; Año: 2010 vol. 95 p. 768 - 775

GALLETTI JEREMÍAS; CAÑONES CRISTIAN; MORANDE PABLO; BORGE MERCEDES; OPPEZZO PABLO; GEFFNER JORGE; BEZARES FERNANDO RAIMUNDO; GAMBERALE ROMINA; GIORDANO MIRTA

Chronic lymphocytic leukemia cells bind and present the erythrocyte protein band 3: possible role as initiators of autoimmune hemolytic anemia.

JOURNAL OF IMMUNOLOGY; Año: 2008 vol. 181 p. 3674 - 3683

GABELLONI MARÍA LAURA; BORGE MERCEDES; GALLETTI JEREMÍAS; CAÑONES CRISTIAN; BEZARES FERNANDO; AVALOS SANCHEZ JULIO; GIORDANO MIRTA; GAMBERALE ROMINA

SHIP-1 protein level and phosphorylation status differs between CLL cells segregated by ZAP-70 expression.

BRITISH JOURNAL OF HAEMATOLOGY; Año: 2008 vol. 140 p. 117 - 119