VÁZQUEZ, RAMIRO; RIVEIRO, MARIA E.; BERENGUER-DAIZÉ, CAROLINE; O?KANE, ANTHONY; GORMLEY, JULIE; TOUZELET, OLIVIER; REZAI, KEYVAN; BEKRADDA, MOHAMED; OUAFIK, L?HOUCINE

Targeting Adrenomedullin in Oncology: A Feasible Strategy With Potential as Much More Than an Alternative Anti-Angiogenic Therapy

Frontiers in Oncology; Año: 2021 vol. 10

SIGAUD, ROMAIN; DUSSAULT, NADÈGE; BERENGUER-DAIZÉ, CAROLINE; VELLUTINI, CHRISTINE; BENYAHIA, ZOHRA; CAYOL, MYLÈNE; PARAT, FABRICE; MABROUK, KAMEL; VÁZQUEZ, RAMIRO; RIVEIRO, MARIA E.; METELLUS, PHILIPPE; OUAFIK, LHOUCINE

Role of the Tyrosine Phosphatase SHP-2 in Mediating Adrenomedullin Proangiogenic Activity in Solid Tumors

Frontiers in Oncology; Año: 2021 vol. 11

SESTITO, SIMONA; BACCI, ANDREA; CHIARUGI, SARA; RUNFOLA, MASSIMILIANO; GADO, FRANCESCA; MARGHERITIS, ELEONORA; GUL, SHERAZ; RIVEIRO, MARIA E.; VAZQUEZ, RAMIRO; HUGUET, SAMUEL; MANERA, CLEMENTINA; REZAI, KEYVAN; GARAU, GIANPIERO; RAPPOSELLI, SIMONA

Development of potent dual PDK1/AurA kinase inhibitors for cancer therapy: Lead-optimization, structural insights, and ADME-Tox profile

EUROPEAN JOURNAL OF MEDICAL CHEMISTRY; Lugar: Paris; Año: 2021

VÁZQUEZ, RAMIRO; CIVENNI, GIANLUCA; SHINCE, DHEERAJ; CANTERGIANI, JASMINE; MARCHETTI, MARTINA; ZOPPI, GIADA; KOKANOVIC, ALEKSANDRA; MERULLA, JESSICA; ALBINO, DOMENICO; RUGGERI, BRUCE; LIU, PHILLIP; CARBONE, GIUSEPPINA M.; CATAPANO, CARLO V.

Efficacy of novel BET inhibitors in combination chemotherapy for castrationresistant prostate cancer

European Urology Oncology; Lugar: Ámsterdam; Año: 2021

GOLDIN, CARLA J.; VÁZQUEZ, RAMIRO; POLACK, FERNANDO P.; ALVAREZ-PAGGI, DAMIAN

Identifying pathophysiological bases of disease in COVID-19

Translational Medicine Communications; Año: 2020 vol. 5

CIVENNI, GIANLUCA; ALBINO, DOMENICO; SHINDE, DHEERAJ; VÁZQUEZ, RAMIRO; MERULLA, JESSICA; KOKANOVIC, ALEKSANDRA; MAPELLI, SARAH NATALIA; CARBONE, GIUSEPPINA M.; CATAPANO, CARLO V.

Transcriptional Reprogramming and Novel Therapeutic Approaches for Targeting Prostate Cancer Stem Cells

Frontiers in Oncology; Año: 2019 vol. 9

CIVENNI, GIANLUCA; BOSOTTI, ROBERTO; TIMPANARO, ANDREA; VÁZQUEZ, RAMIRO; MERULLA, JESSICA; PANDIT, SHUSIL; ROSSI, SIMONA; ALBINO, DOMENICO; ALLEGRINI, SARA; MITRA, ABHISHEK; MAPELLI, SARAH NATALIA; VIERLING, LUCA; GIURDANELLA, MARTINA; MARCHETTI, MARTINA; PAGANONI, ALYSSA; RINALDI, ANDREA; LOSA, MARCO; MIRA-CATÓ, ENRICA; D'ANTUONO, ROCCO; MORONE, DIEGO; REZAI, KEYVAN; D'AMBROSIO, GIOACCHINO; OUAFIK, L'HOUCINE; MACKENZIE, SARAH; RIVEIRO, MARÍA EUGENIA; CVITKOVIC, ESTEBAN; CARBONE, GIUSEPPINA M.; CATAPANO, CARLO V.

Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer

CELL METABOLISM; Lugar: United States; Año: 2019

VÁZQUEZ, RAMIRO; ASTORGUES-XERRI, LUCILE; ODORE, ELODIE; KAHATT, CARMEN; MACKENZIE, SARAH; BEKRADDA, MOHAMED; COUDÉ, MARIE-MAGDELAINE; DOMBRET, HERVE; GARDIN, CLAUDE; LOKIEC, FRANCOIS; RAYMOND, ERIC; NOEL, KAY; CVITKOVIC, ESTEBAN; HERAIT, PATRICE; BERTONI, FRANCESCO; RIVEIRO, MARÍA EUGENIA

Insights into the cellular pharmacological properties of the BETinhibitor OTX015/MK-8628 (birabresib), alone and in combination, in leukemia models

LEUKEMIA AND LYMPHOMA; Lugar: Londres; Año: 2019

MONDILLO, CAROLINA; VARELA, MARÍA LUISA; ABIUSO, ADRIANA MARÍA BELÉN; VÁZQUEZ, RAMIRO

Potential negative effects of anti-histamines on male reproductive function

REPRODUCTION; Año: 2018 vol. 155 p. 221 - 227

VÁZQUEZ, RAMIRO; LICANDRO, SIMONETTA ANDREA; ASTORGUES-XERRI, LUCILE; LETTERA, EMANUELE; PANINI, NICOLÒ; ROMANO, MICHELA; ERBA, EUGENIO; UBEZIO, PAOLO; BELLO, EZIA; LIBENER, ROBERTA; ORECCHIA, SARA; GROSSO, FEDERICA; RIVEIRO, MARÍA EUGENIA; CVITKOVIC, ESTEBAN; BEKRADDA, MOHAMED; D'INCALCI, MAURIZIO; FRAPOLLI, ROBERTA

Promising in vivo efficacy of the BET bromodomain inhibitor OTX015/MK-8628 in malignant pleural mesothelioma xenografts

INTERNATIONAL JOURNAL OF CANCER. JOURNAL INTERNATIONAL DU CANCER.; Año: 2017 vol. 140 p. 197 - 207

RIVEIRO, MARÍA EUGENIA; ASTORGUES-XERRI, LUCILE; VÁZQUEZ, RAMIRO; FRAPOLLI, ROBERTA; KWEE, IVO; RINALDI, ANDREA; ODORE, ELODIE; REZAI, KEYVAN; BEKRADDA, MOHAMED; INGHIRAMI, GIORGIO; D'INCALCI, MAURIZIO; NOEL, KAY; CVITKOVIC, ESTEBAN; RAYMOND, ERIC; BERTONI, FRANCESCO

OTX015 (MK-8628), a novel BET inhibitor, exhibits antitumor activity in non-small cell and small cell lung cancer models harboring different oncogenic mutations

Oncotarget; Año: 2016

VÁZQUEZ, RAMIRO; RIVEIRO, MARÍA EUGENIA; ASTORGUES-XERRI, LUCILE; ODORE, ELODIE; REZAI, KEYVAN; ERBA, EUGENIO; PANINI, NICOLÒ; RINALDI, ANDREA; KWEE, IVO; BELTRAME, LUCA; BEKRADDA, MOHAMED; CVITKOVIC, ESTEBAN; BERTONI, FRANCESCO; FRAPOLLI, ROBERTA; D'INCALCI, MAURIZIO

The bromodomain inhibitor OTX015 (MK-8628) exerts anti-tumor activity in triple-negative breast cancer models as single agent and in combination with everolimus

Oncotarget; Año: 2016

VÁZQUEZ, RAMIRO; ASTORGUES-XERRI, LUCILE; BEKRADDA, MOHAMED; GORMLEY, JULIE; BUICK, RICHARD; KERR, PAUL; CVITKOVIC, ESTEBAN; RAYMOND, ERIC; D'INCALCI, MAURIZIO; FRAPOLLI, ROBERTA; RIVEIRO, MARÍA EUGENIA

Fsn0503h antibody-mediated blockade of cathepsin S as a potential therapeutic strategy for the treatment of solid tumors

BIOCHIMIE; Año: 2014 vol. 108 p. 101 - 107

VÁZQUEZ, RAMIRO; RIVEIRO, MARÍA EUGENIA; MONDILLO, CAROLINA; PERAZZO, JUAN CARLOS; VERMULEN, MÓNICA; BALDI, ALBERTO; DAVIO, CARLOS; SHAYO, CARINA

Pharmacodynamic study of the 7,8-dihydroxy-4-methylcoumarininduced selective cytotoxicity toward U-937 leukemic cells versus mature monocytes: Cytoplasmic p21Cip1/WAF1 as resistance factor

BIOCHEMICAL PHARMACOLOGY; Año: 2013 vol. 86 p. 210 - 221

VÁZQUEZ, RAMIRO; RIVEIRO, MARÍA EUGENIA; VERMULEN, MÓNICA; MONDILLO, CAROLINA; COOMBES, PHILIP H.; CROUCH, NEIL R.; ISMAIL, FATHIMA; MULHOLLAND, DULCIE A.; BALDI, ALBERTO; SHAYO, CARINA; DAVIO, CARLOS

Toddaculin, a natural coumarin from Toddalia asiatica, induces differentiation and apoptosis in U-937 leukemic cells

PHYTOMEDICINE; Lugar: Ámsterdam; Año: 2012 vol. 19 p. 737 - 746

VÁZQUEZ, RAMIRO; RIVEIRO, MARÍA EUGENIA; VERMULEN, MÓNICA; ALONSO, ELIANA; MONDILLO, CAROLINA; FACORRO, GRACIELA; PIEHL, LIDIA; GÓMEZ, NATALIA; MOGLIONI, ALBERTINA; FERNÁNDEZ, NATALIA; BALDI, ALBERTO; SHAYO, CARINA; DAVIO, CARLOS

Structure-anti-leukemic activity relationship study of ortho- dihydroxycoumarins in U-937 cells: Key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action

BIOORGANIC & MEDICINAL CHEMISTRY.; Lugar: Ámsterdam; Año: 2012 vol. 20 p. 5537 - 5549

GÓMEZ, NATALIA; SANTOS, DIEGO; VÁZQUEZ, RAMIRO; SUESCÚN, LEOPOLDO; MOMBRÚ, ÁLVARO; VERMEULEN, MÓNICA; FINKIELSZTAIN, LILIANA; SHAYO, CARINA; MOGLIONI, ALBERTINA; GAMBINO, DINORAH; DAVIO, CARLOS

Synthesis, Structural Characterization, and Pro-apoptotic Activity of 1-Indanone Thiosemicarbazone Platinum(II) and Palladium(II) Complexes: Potential as Antileukemic Agents

CHEMMEDCHEM; Año: 2011 vol. 6 p. 1485 - 1494

RIVEIRO, MARÍA EUGENIA; DE KIMPE, NORBERT; MOGLIONI, ALBERTINA; VÁZQUEZ, RAMIRO; MONCZOR, FEDERICO; SHAYO, CARINA; DAVIO, CARLOS

Coumarins: Old compounds with novel promising therapeutic perspectives

CURRENT MEDICINAL CHEMISTRY.; Año: 2010 vol. 17 p. 1325 - 1338

RIVEIRO, MARÍA EUGENIA; MAES, DOMINICK; VÁZQUEZ, RAMIRO; VERMULEN, MÓNICA; MAGELINCKX, SVEN; JACOBS, JAN; DEBENEDETTI, SILVIA; SHAYO, CARINA; DE KIMPE, NORBERT; DAVIO, CARLOS

Toward establishing structure?activity relationships for oxygenated coumarins as differentiation inducers of promonocytic leukemic cells

BIOORGANIC & MEDICINAL CHEMISTRY.; Lugar: Amsterdam; Año: 2009

RIVEIRO, MARÍA EUGENIA; MOGLIONI, ALBERTINA; VÁZQUEZ, RAMIRO; GÓMEZ, NATALIA; FACORRO GRACIELA; PIEHL LIDIA; RUBIN DE CELIS EMILIO; SHAYO, CARINA; DAVIO, CARLOS

Structural insights into hydroxycoumarins-induced apoptosis in U-937 cells.

BIOORGANIC & MEDICINAL CHEMISTRY.; Lugar: Ámsterdam; Año: 2008 vol. 16 p. 2665 - 2675

RIVEIRO, MARÍA EUGENIA; VÁZQUEZ, RAMIRO; MOGLIONI, ALBERTINA; GÓMEZ, NATALIA; BALDI ALBERTO; DAVIO, CARLOS; SHAYO, CARINA

Biochemical mechanisms underlying the pro-apoptotic activity of 7,8-dihidroxy-4-methylcoumarin in human leukemic cells

BIOCHEMICAL PHARMACOLOGY; Lugar: Ámsterdam; Año: 2008 vol. 75 p. 725 - 736