NIEMIROWICZ, GABRIELA T.; CARLEVARO, GIANNINA; CAMPETELLA, OSCAR; BOUVIER, LEÓN A.; MUCCI, JUAN

A versatile 2A peptide-based strategy for ectopic expression and endogenous gene tagging in Trypanosoma cruzi

Heliyon; Año: 2024 vol. 10

ALVAREZ, VANINA E.; IRIBARREN, PAULA A.; NIEMIROWICZ, GABRIELA T.; CAZZULO, JUAN JOSÉ

Update on relevant trypanosome peptidases: Validated targets and future challenges

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS; Año: 2021 vol. 1869

SALAS-SARDUY, EMIR; LANDABURU, LIONEL URÁN; CARMONA, ADRIANA K.; CAZZULO, JUAN JOSÉ; AGÜERO, FERNÁN; ALVAREZ, VANINA E.; NIEMIROWICZ, GABRIELA T.

Potent and selective inhibitors for M32 metallocarboxypeptidases identified from high-throughput screening of anti-kinetoplastid chemical boxes

PLOS NEGLECTED TROPICAL DISEASES; Año: 2019 vol. 13

SALAS-SARDUY, EMIR; NIEMIROWICZ, GABRIELA T.; JOSÉ CAZZULO, JUAN; ALVAREZ, VANINA EDER

Target-based screening of the Chagas box: setting up enzymatic assays to discover specific inhibitors across bioactive compounds

CURRENT MEDICINAL CHEMISTRY.; Año: 2019 vol. 26

NIEMIROWICZ, GABRIELA T.; CAZZULO, JUAN J.; ÁLVAREZ, VANINA E.; BOUVIER, LEÓN A.

Simplified inducible system for Trypanosoma brucei

PLOS ONE; Año: 2018 vol. 13

BOUVIER, LEÓN A.*; NIEMIROWICZ, GABRIELA T.*; SALAS-SARDUY, EMIR; CAZZULO, JUAN JOSÉ; ALVAREZ, VANINA E.

DNA-damage inducible protein 1 is a conserved metacaspase substrate that is cleaved and further destabilized in yeast under specific metabolic conditions

FEBS JOURNAL; Año: 2018

FRASCH, ALEJANDRA P.; BOUVIER, LEÓN A.; OPPENHEIMER, FLORENCIA M.; JULIANO, MARIA APARECIDA; JULIANO, LUIZ; CARMONA, ADRIANA K.; CAZZULO, JUAN JOSÉ; NIEMIROWICZ, GABRIELA T.

Substrate specificity profiling of M32 metallocarboxypeptidases from Trypanosoma cruzi and Trypanosoma brucei

MOLECULAR AND BIOCHEMICAL PARASITOLOGY; Año: 2017

ALVAREZ, VANINA EDER; NIEMIROWICZ, GABRIELA TERESA; CAZZULO, JUAN JOSÉ

Metacaspases, Autophagins and Metallocarboxypeptidases: Potential New Targets for Chemotherapy of the Trypanosomiases.

CURRENT MEDICINAL CHEMISTRY.; Lugar: Oak Park; Año: 2013

ALVAREZ, VANINA EDER; NIEMIROWICZ, GABRIELA TERESA; CAZZULO, JUAN JOSÉ

The peptidases of Trypanosoma cruzi: Digestive enzymes, virulence factors, and mediators of autophagy and programmed cell death.

BIOCHIMICA ET BIOPHYSICA ACTA (ENZIMOLOGY); Año: 2012 p. 195 - 206

ALEJANDRA PAULA FRASCH; ADRIANA CARMONA; JULIANO, LUIZ; JUAN JOSÉ CAZZULO; GABRIELA TERESA NIEMIROWICZ

Characterization of the M32 metallocarboxypeptidase of Trypanosoma brucei: differences and similarities with its orthologue in Trypanosoma cruzi.

MOLECULAR AND BIOCHEMICAL PARASITOLOGY; Lugar: Amsterdam; Año: 2012

NIEMIROWICZ G, FERNÁNDEZ D, SOLÀ M, CAZZULO JJ, AVILÉS FX, GOMIS-RÜTH FX.

The molecular analysis of Trypanosoma cruzi metallocarboxypeptidase 1 provides insight into fold and substrate specificity

MOLECULAR MICROBIOLOGY; Año: 2008 vol. 7 p. 853 - 866

GABRIELA NIEMIROWICZ, FABIOLA PARUSSINI, FERNÁN AGÜERO, AND JUAN J. CAZZULO

Two metallocarboxypeptidases from the protozoan Trypanosoma cruzi belong to the M32 family, found so far only in prokaryotes.

BIOCHEMICAL JOURNAL; Año: 2007 vol. 401 p. 399 - 410