Bioactive peptides released from pseudo-cereals proteins during gastrointestinal digestion

AÑÓN MC; GARCÍA FILLERÍA S; NARDO AE; QUIROGA A; RODRÍGUEZ M; SABBIONE AC; SCILINGO A; SUAREZ S; TIRONI V

Protein digestion-derived peptides: chemistry, bioactivity, and health effects

Elsevier

Año: 2024;

Pseudo-cereals comprise a group of ancient grains such as amaranth, buckwheat, chia, canihua, and quinoa. A large number of studies demonstrating in vitro various bioactivities of peptides derived from their proteins can be found in the literature. However, most of these studies do not include the simulation of the gastrointestinal digestion process (SGID), essential to assess the bio accessibility and bioactivity of the compounds. This chapter presents results found in the literature related to proteins, flours, or food matrices from pseudo-cereals subjected to SGID, focusing on the most frequently studied bioactivities: antioxidant, anti-inflammatory, anti-proliferative, anti-hypertensive, hypocholesterolemic, anticoagulant and anti-diabetic. Although the existing studies suggest promising healthy properties, the evidence is still scarce and it is necessary to increase the number of research papers as well as to deepen the studies of bioaccessibility, intestinal absorption, and mechanisms of action. Amaranth seems to be the most studied pseudo-cereal up to now.