INVESTIGADORES
PEREYRA Carina Maricel
congresos y reuniones científicas
Título:
Antimicrobial activity of carbohydrate chitosan derivatives
Autor/es:
DÍAZ VERGARA L.; ARATA BADANO J.; BRESER L.; PORPORATTO C.; PEREYRA C.M.; CAVAGLIERI L.R.; MONTENEGRO M.A.
Lugar:
Mar del Plata
Reunión:
Congreso; XVI Simposio Latinoamericano de Polímeros y XIV Congreso Iberoamericano de Polímeros; 2018
Institución organizadora:
SLAP 2018
Resumen:
Chitosan (Ch) is a polysaccharide composed of β- (1→4)-N-acetyl-2-amino-2-deoxy-D-glucose and 2- amino-2-deoxy-D-glucose obtained from the alkaline deacetylation of chitin1 . It is a natural, biocompatible, biodegradable, antioxidant, antimicrobial, non-toxic, mucoadhesive, antitumor compound2 . Antimicrobial activity of Ch has been attributed to the molecular weight (MW) and the –NH2 gropus3. However, this property is limited by the low solubility of Ch4. The modification with carbohydrates can improve the solubility5. The aims of this study were to evaluate the antimicrobial activity of different carbohydrate Ch derivatives against Staphylococcus aureus, Escherichia coli and Enterococcus faecalis.