CASTILLO, ANA F.; PODEROSO, CECILIA; MALOBERTI, PAULA M.; CORNEJO MACIEL, FABIANA; MORI SEQUEIROS GARCIA, MM; ORLANDO, ULISES; MELE, PABLO G.; BENZO, YANINA; DATTILO, MELINA A.; PRADA, JESICA G.; QUEVEDO, LUCIANO; BELLUNO, MATIAS; PAZ, CRISTINA; PODESTA, ERNESTO J.

Specific cellular microenvironments for spatiotemporal regulation of StAR and steroid synthesis

Journal of Endocrinology; Año: 2024 vol. 261

RÍOS MEDRANO, MAYRA A.; BIGI, MARÍA M.; MARTÍNEZ PONCE, PALOMA; PODESTA, ERNESTO J.; ORLANDO, ULISES D.

Exposure to anticancer drugs modulates the expression of ACSL4 and ABCG2 proteins in adrenocortical carcinoma cells

Heliyon; Lugar: Massachusetts; Año: 2023 vol. 9

ANGELA R. SOLANO, PABLO G. MELE, FERNANDA S. JALIL, NATALIA C. LIRIA, ERNESTO J. PODESTA AND LEANDRO G. GUTIÉRREZ.

Study of the Genetic Variants in BRCA1/2 and Non-BRCA Genes in a Population-Based Cohort of 2155 Breast/Ovary Cancer Patients, Including 443 Triple-Negative Breast Cancer Patients, in Argentina

Cancers; Lugar: Basel; Año: 2021 vol. 13

CASTILLO, ANA F.; ORLANDO, ULISES D.; MALOBERTI, PAULA M.; PRADA, JESICA G.; DATTILO, MELINA A.; SOLANO, ANGELA R.; BIGI, MARÍA M.; RÍOS MEDRANO, MAYRA A.; TORRES, MARÍA T.; INDO, SEBASTIÁN; CAROCA, GRACIELA; CONTRERAS, HECTOR R.; MARELLI, BELKIS E.; SALINAS, FACUNDO J.; SALVETTI, NATALIA R.; ORTEGA, HUGO H.; LORENZANO MENNA, PABLO; SZAJNMAN, SERGIO; GOMEZ, DANIEL E.; RODRÍGUEZ, JUAN B.; PODESTA, ERNESTO J.

New inhibitor targeting Acyl-CoA synthetase 4 reduces breast and prostate tumor growth, therapeutic resistance and steroidogenesis

CELL. MOLEC. LIFE SCIEN.; Lugar: Basel; Año: 2021 vol. 78 p. 2893 - 2910

HELFENBERGER, KATIA E.; CASTILLO, ANA F.; MELE, PABLO G.; FIORE, ANA; HERRERA, LUCÍA; FINOCCHIETTO, PAOLA; PODESTÁ, ERNESTO J.; PODEROSO, CECILIA

Angiotensin II stimulation promotes mitochondrial fusion as a novel mechanism involved in protein kinase compartmentalization and cholesterol transport in human adrenocortical cells

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY; Año: 2019

ORLANDO UD,CASTILLO AF,MEDRANO MAR,SOLANO AR,MALOBERTI PM,PODESTA EJ.

Acyl-CoA synthetase-4 is implicated in drug resistance in breast cancer cell lines involving the regulation of energy-dependent transporter expression

BIOCHEMICAL PHARMACOLOGY; Lugar: Amsterdam; Año: 2019 vol. 159 p. 52 - 63

PODESTA, ERNESTO J.

BRCA1 and BRCA2 mutations and clinical interpretation in 398 ovarian cancer patients: comparison with breast cancer variants in a similar population

human genomic; Año: 2018 vol. 12

ANGELA R. SOLANO1,2*, NATALIA C. LIRIA1, FERNANDA S. JALIL1, DANIELA M. FAGGIONATO1, PABLO G. MELE2, ALEJANDRA MAMPEL3, FLORENCIA C. CARDOSO1 AND ERNESTO J. PODESTA2.

BRCA1 and BRCA2 Mutations Other Than the Founder Alleles Among Ashkenazi Jewish in the Population of Argentina

Frontier in Oncology; Año: 2018 vol. 8

ANGELA ROSARIA SOLANO; FLORENCIA CECILIA CARDOSO; VANESA ROMANO; FLORENCIA PERAZZO; CARLOS BAS; GONZALO RECONDO; FRANCISCO BERNARDO SANTILLAN; EDUARDO GONZALEZ; EDUARDO ABALO; MARÍA VINIEGRA; JOSÉ DAVALOS MICHEL; LINA MARÍA NUÑEZ; CRISTINA MARIA NOBLIA; IGNACIO MC LEAN; ENRIQUE DIAZ CANTON; REINALDO DANIEL CHACON; GUSTAVO CORTESE; EDUARDO BECCAR VARELA; MARTÍN GRECO; MARÍA LAURA BARRIENTOS; SILVIA ADELA AVILA; HECTOR DANIEL VUOTTO; ANTONIO LORUSSO; ERNESTO JORGE PODESTA; OSCAR GASPAR MANDO

Spectrum of BRCA1/2 variants in 940 patients from Argentina including novel, deleterious and recurrent germline mutations: impact on healthcare and clinical practice

Oncotarget; Año: 2016

CRISTINA PAZ; FABIANA CORNEJO MACIEL; ANA F. CASTILLO; ALEJANDRA GOROSTIZAGA; M. MERCEDES MORI SEQUEIROS GARCÍA; PAULA M. MALOBERTI; ULISES D. ORLANDO; PABLO G. MELE; CECILIA PODEROSO; ERNESTO J. PODESTA

Role of Protein Phosphorylation and Tyrosine Phosphatases in the Adrenal Regulation of Steroid Synthesis and Mitochondrial Function

Frontiers in Endocrinology; Año: 2016 p. 1 - 10

GARONA J, PIFANO; M, ORLANDO UD; PASTRIAN MB; IANNUCCI NB; ORTEGA HH; PODESTA EJ; GOMEZ DE; RIPOLL GV; ALONSO DF

The novel desmopressin analogue [V4Q5]dDAVP inhibits angiogenesis, tumour growth and metastases in vasopressin type 2 receptor-expressing breast cancer models.

INTERNATIONAL JOURNAL OF ONCOLOGY; Lugar: Atenas; Año: 2015

ULISES ORLANDO ; ANA F. CASTILLO; MELINA A. DATTILO; ANGELA R. SOLANO; PAULA M. MALOBERTI; ERNESTO J. PODESTA

Acyl-CoA synthetase-4, a new regulator of mTOR and a potential therapeutic target for enhanced estrogen receptor function in receptor-positive and -negative breast cancer

Oncotarget; Año: 2015

ANA F. CASTILLO; ULISES D. ORLANDO ; PAULA LOPEZ; ANGELA R. SOLANO; PAULA M. MALOBERTI ; ERNESTO J. PODESTA

Gene Expression Profile and Signaling Pathways in MCF-7 Breast Cancer Cells Mediated by Acyl-CoA Synthetase 4 Overexpression

Transcriptomics; Lugar: Los Angeles; Año: 2015

CASTILLO AF, ORLANDO U, HELFENBERGER KE, PODEROSO C, PODESTA EJ.

The role of mitochondrial fusion and StAR phosphorylation in the regulation of StAR activity and steroidogenesis.

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Lugar: Amsterdam; Año: 2014 p. 73 - 79

DUARTE A, CASTILLO AF, PODESTÁ EJ, PODEROSO C.

Mitochondrial fusion and ERK activity regulate steroidogenic acute regulatory protein localization in mitochondria.

PLOS ONE; Lugar: San Francisco; Año: 2014 p. 1 - 10

PODEROSO C, DUARTE A, COOKE M, ORLANDO U, GOTTIFREDI V, SOLANO AR, LEMOS JR, PODESTÁ EJ.

The spatial and temporal regulation of the hormonal signal. Role of mitochondria in the formation of a protein complex required for the activation of cholesterol transport and steroids synthesis.

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Lugar: Amsterdam; Año: 2013 vol. 371 p. 26 - 33

GÓMEZ NV, GOROSTIZAGA AB, MORI SEQUEIROS GARCÍA MM, BRION L, ACQUIER A, GONZÁLEZ-CALVAR SI, MÉNDEZ CF, PODESTÁ EJ, PAZ C.

MAPK phosphatase-2 (MKP-2) is induced by hCG and plays a role in the regulation of CYP11A1 expression in MA-10 Leydig cells.

ENDOCRINOLOGY; Año: 2013 vol. 154 p. 1488 - 1500

ORLANDO U, COOKE M, CORNEJO MACIEL FC, PAPADOPOULOS V, PODESTÁ EJ, MALOBERTI P.

Characterization of the mouse promoter region of the acyl-CoA synthetase 4 gene: role of Sp1 and CREB.

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Lugar: Amsterdam; Año: 2013 vol. 369 p. 15 - 26

MELE PG, DUARTE A, PAZ C, CAPPONI A, PODESTÁ EJ.

Role of intramitochondrial arachidonic acid and acyl-CoA synthetase 4 in angiotensin II-regulated aldosterone synthesis in NCI-H295R adrenocortical cell line.

ENDOCRINOLOGY; Año: 2012 vol. 153 p. 3284 - 3294

DUARTE A, PODEROSO C, COOKE M, SORIA G, CORNEJO MACIEL F, GOTTIFREDI V, PODESTÁ EJ.

Mitochondrial fusion is essential for steroid biosynthesis.

PLOS ONE; Lugar: San Francisco; Año: 2012 vol. 7 p. 1 - 8

ORLANDO UD, GARONA J, RIPOLL GV, MALOBERTI PM, SOLANO ÁR, AVAGNINA A, GOMEZ DE, ALONSO DF, PODESTÁ EJ.

The functional interaction between Acyl-CoA synthetase 4, 5-lipooxygenase and cyclooxygenase-2 controls tumor growth: a novel therapeutic target.

PLOS ONE; Lugar: San Francisco; Año: 2012 vol. 7 p. 1 - 35

PERONI, ABRAMOF, NEUMAN, PODESTA, ADLER

Phytoestrogens Enhance the Vascular Actions of the Endocannabinoid Anandamide in Mesenteric Beds of Female Rats,

International journal of hypertension; Lugar: New York; Año: 2012 p. 1 - 10

SOLANO, A.R., ACETO, G.M., DELETTIERES, D., VESCHI, S., NEUMAN, M.I., ALONSO, E., CHIALINA, S., CHACÓN, R., MARIANI-CONSTANTINI, R., PODESTÁ, E.J.

BRCA1 And BRCA2 analysis of Argentinean breast/ovarian cancer patients selected for age and family history highlights a role for novel mutations of putative south-American origin

SpringerPlus-SpringerOpen Journal; Año: 2012 vol. 1 p. 1 - 10

COOKE M, ORLANDO U, MALOBERTI P, PODESTÁ EJ, MACIEL FC

Tyrosine phosphatase SHP2 regulates the expression of acyl-CoA synthetase ACSL4.

JLR PAPERS IN PRESS; Lugar: Bethesda, Maryland; Año: 2011 vol. 52 p. 1936 - 1948

COOKE M, MELE P, MALOBERTI P, DUARTE A, PODEROSO C, ORLANDO U, PAZ C, CORNEJO MACIEL F, PODESTÁ EJ.

Tyrosine phosphatases as key regulators of StAR induction and cholesterol transport: SHP2 as a potential tyrosine phosphatase involved in steroid synthesis.

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Año: 2011 vol. 336 p. 63 - 69

ANA FERNANDA CASTILLO, JINJIANG FAN, VASSILIOS PAPADOPOULOS, AND ERNESTO J. PODESTA

Hormone-Dependent Expression of a Steroidogenic Acute Regulatory Protein Natural Antisense Transcript in MA-10 Mouse Tumor Leydig Cells

PLOS ONE; Lugar: San Francisco; Año: 2011 vol. 6 p. 1 - 5

LAURA BRION, PAULA M. MALOBERTI, NATALIA V. GOMEZ, CECILIA PODEROSO ALEJANDRA B. GOROSTIZAGA, MARIA M. MORI SEQUEIROS GARCIA, ANDREA B. ACQUIER MARIANA COOKE, CARLOS F. MENDEZ, ERNESTO J. PODESTA, AND CRISTINA PAZ

MAPK Phosphatase-1 (MKP-1) Expression Is

ENDOCRINOLOGY; Año: 2011 vol. 152

ACETO GM, SOLANO AR, NEUMAN MI, VESCHI S, MORGANO A, MALATESTA S, CHACON RD, PUPARELI C, LOMBARDI M, BATTISTA P, MARCHETTI A, MARIANI-COSTANTINI R, PODESTA E J.

High-risk human papilloma virus infection, tumor pathophenotypes, and BRCA1/2 and TP53 status in juvenile breast cancer.

BREAST CANCER RESEARCH AND TREATMENT; Año: 2010 vol. 122 p. 671 - 683

PAULA M. MALOBERTI,1 ALEJANDRA B. DUARTE,1 ULISES D. ORLANDO,1 MARÍA E. PASQUALINI,2 ÁNGELA R. SOLANO,1 CARLOS LÓPEZ-OTÍN,3 AND ERNESTO J. PODESTÁ

Functional Interaction between Acyl-CoA Synthetase 4, Lipooxygenases and Cyclooxygenase-2 in the Aggressive Phenotype of Breast Cancer Cells

PLOS ONE; Año: 2010 p. 15540 - 15540

BRION L, GOROSTIZAGA A, GÓMEZ NV, PODESTÁ EJ, CORNEJO MACIEL F, PAZ C

Valproic acid alters mitochondrial colesterol transport in Y1 adrenocortical cells.

TOXICOLOGY IN VITRO : AN INTERNATIONAL JOURNAL PUBLISHED IN ASSOCIATION WITH BIBRA.; Año: 2010 vol. 25 p. 7 - 12

PAZ C, PODEROSO C, MALOBERTI P, MACIEL FC, MENDEZ C, PODEROSO JJ, PODESTÁ EJ.

Detection of a mitochondrial kinase complex that mediates PKA-MEK-ERK-dependent phosphorylation of mitochondrial proteins involved in the regulation of steroid biosynthesis.

METHODS IN ENZYMOLOGY.; Año: 2009 vol. 457 p. 169 - 192

PODEROSO C, MALOBERTI P, DUARTE A, NEUMAN I, PAZ C, MACIEL FC, PODESTA EJ.

Hormonal activation of a kinase cascade localized at the mitochondria is required for StAR protein activity.

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Año: 2009 p. 37 - 42

CECILIA PODEROSO, DANIELA P. CONVERSO, PAULA MALOBERTI, ALEJANDRA DUARTE, ISABEL NEUMAN, SOLEDAD GALLI, FABIANA CORNEJO MACIEL, CRISTINA PAZ, MARÍA C. CARRERAS, JUAN J. PODEROSO, ERNESTO J. PODESTÁ.

A Mitochondrial Kinase Complex Is Essential to Mediate an ERK1/2-Dependent Phosphorylation of a Key Regulatory Protein in Steroid Biosynthesis.

PLOS ONE; Lugar: San Francisco, Californoa , USA; Año: 2008 p. 1 - 11

A. CASTILLO, R CASTILLA, A DUARTE, P MELE, U ORLANDO, I NEUMANM, H DI CONSOLI, C PODEROSO, A SOLANO, C FINKELSTEIN, P MALOBERTI, F CORNEJO MACIEL, C PAZ ANS E J PODESTA

Review: Intramitochondrial arachidonic acid as regulator of two different cellular functions: steroid biosynthesis and tumor cell proliferation.

Current Trends in Endocrinology; Año: 2008 vol. 3 p. 57 - 71

C PODEROSO, P MALOBERTI, A DUARTE, R CASTILLA, I NEUMAN, C PAZ, F CORNEJO MACIEL, E J PODESTA

Review: The Steroidogenic Acute Regulatory (StAR) protein as target for multiple kinases. Roles of protein phosphorylation on StAR function.

Current Topic in Steroid Research; Año: 2008 vol. 5 p. 35 - 49

R. CASTILLA; M. GADALETA; F. CASTILLO; A. DUARTE; I. NEUMAN; C. PAZ; F. CORNEJO MACIEL; E.J. PODESTÁ

New Enzymes Involved in the Mechanism of Action of Epidermal Growth Factor in a Clonal Strain of Leydig Tumor Cells

ENDOCRINOLOGY; Año: 2008 p. 113 - 120

P. MALOBERTI; F. CORNEJO MACIEL; F. CASTILLO; R. CASTILLA; A. DUARTE; F. TOLEDO; F. MEULI; P. MELE; C. PAZ; E.J. PODESTÁ

Enzymes involved in arachidonic acid release in adrenal and Leydig cells

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Año: 2007 vol. 265 p. 113 - 120

A. GOROSTIZAGA; F. CORNEJO MACIEL; L. BRION; P. MALOBERTI; E.J. PODESTÁ; C. PAZ

Tyrosine phosphatases in steroidogenic cells: regulation and function

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Año: 2007 vol. 265 p. 131 - 137

A. DUARTE; F. CASTILLO; R. CASTILLA; P. MALOBERTI; C. PAZ; E.J. PODESTÁ; F. CORNEJO MACIEL

An arachidonic acid generation/export system involved in the regulation of cholesterol transport in mitochondria of steroidogenic cells

FEBS LETTERS; Año: 2007 vol. 581 p. 4023 - 4028

C. PODEROSO; D. CONVERSO; P. MALOBERTI; A. DUARTE; I. NEUMAN; S. GALLI; F. CORNEJO MACIEL; C. PAZ; C. CARRERAS; J.J. PODEROSO; E.J. PODESTÁ

A Mitochondrial Kinase Complex Is Essential to Mediate an ERK1/2-Dependent Phosphorylation of a Key Regulatory Protein in Steroid Biosynthesis

PLOS ONE; Año: 2007

M.L. ORLIAC; R.N. PERONI; T. ABRAMOFF; I. NEUMAN; E.J. PODESTÁ; E. ADLER-GRASCHINSKY

Increases in vanilloid TRPV1 receptor protein and CGRP content during endotoxemia in rats

Eur J Pharmacol; Año: 2007 vol. 566 p. 145 - 152

F. CANO; C. PODEROSO; F. CORNEJO MACIEL; R. CASTILLA; P. MALOBERTI; F. CASTILLO; I. NEUMAN; C. PAZ; E.J. PODESTÁ

Protein tyrosine phosphatases regulate arachidonic acid release, StAR induction and steroidogenesis acting on a hormone-dependent arachidonic acid-preferring acyl-CoA synthetase

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY; Año: 2006 vol. 99 p. 197 - 202

F. CASTILLO; F. CORNEJO MACIEL; R. CASTILLA; A. DUARTE; P. MALOBERTI; C. PAZ; E.J. PODESTÁ

1. cAMP increases mitochondrial cholesterol transport through the induction of arachidonic acid release inside this organelle in Leydig cells

FEBS JOURNAL; Año: 2006 vol. 273 p. 5011 - 5021

DOURISBOURE RJ; BELLI S; DOMENICHINI E; PODESTÁ EJ; CHARIS E; SOLANO AR.

Penetrance and clinical manifestations of non-hotspot germline RET mutation, c630r, in a family with medullar thyroid carcinoma.

THYROID; Lugar: United States; Año: 2005 vol. 15 p. 668 - 671

GOROSTIZAGA A; BRION L; MALOBERTI P; CORNEJO MACIEL F; PODESTÁ EJ; PAZ C

Heat shock triggers MAPK activation and MKP-1 induction in Leydig testicular cells.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Lugar: United States; Año: 2005 vol. 327 p. 23 - 28

CORNEJO MACIEL F; MALOBERTI P; NEUMAN I; CANO F; CASTILLA R; CASTILLO F; PAZ C; PODESTA EJ.

An arachidonic acid-preferring acyl-CoA synthetase is a hormone-dependent and cicloheximide-sensitive protein obligatory in the signal transduction pathway of steroidogenic hormones.

JOURNAL OF MOLECULAR ENDOCRINOLOGY; Lugar: England; Año: 2005 vol. 34 p. 655 - 666

MALOBERTI PM; CASTILLA R; CASTILLO F; CORNEJO MACIEL F; MENDEZ C; PAZ C; PODESTA EJ

Silencing the expression of mitochondrial acyl-CoA thioesterase I and acyl-CoA synthetase 4 inhibits hormone-induced steroidogenesis.

EUROPEAN JOURNAL OF BIOCHEMISTRY; Lugar: England; Año: 2005 vol. 272 p. 1804 - 1814

HUNT MC; YAMADA J; MALTAIS LJ; WRIGHT M; PODESTA EJ; ALEXSON SE

A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases.

JLR PAPERS IN PRESS; Lugar: United States; Año: 2005 vol. 46 p. 2029 - 2032

DE ROSA M; DOURISBOURE RJ; MORELLI G; GRAZIANO A; GUTIÉRREZ A; THIBODEAU S; HALLING K; COLLIA AVILA K; DURATURO F; PODESTA EJ; IZZO P; SOLANO AR.

First Genotype Characterization of Argentinean FAP Patients: Identification of 14 Novel APC Gene Mutations.

HUMAN MUTATION; Lugar: United States; Año: 2004 vol. 23 p. 523 - 524

CASTILLO F; CANO F; MALOBERTI P; CASTILLA R; NEUMAN I; PODEROSO C; PAZ C; PODESTÁ EJ; CORNEJO MACIEL F

Tyrosine phosphatases act on steroidogenesis through the activation of arachidonic acid release.

ENDOCRINE RESEARCH; Lugar: United States; Año: 2004 vol. 30 p. 623 - 627

CASTILLA R; MALOBERTI P; CASTILLO F; DUARTE A; CANO F; CORNEJO MACIEL F; NEUMAN I; MENDEZ CF; PAZ C; PODESTA EJ

Arachidonic Acid Regulation of Steroid Synthesis: New Partners in the Signaling Pathway of Steroidogenic Hormones.

ENDOCRINE RESEARCH; Lugar: United States; Año: 2004 vol. 30 p. 599 - 606

POMERANIEC Y; GRION N; GADDA L; PANNUNZIO V; PODESTA EJ; CYMERYNG CB

Adrenocorticotropin induces heme oxygenase-1 expression in adrenal cells

JOURNAL OF ENDOCRINOLOGY; Lugar: Gran Bretaña; Año: 2004 vol. 180 p. 113 - 124

COLONNA C; PODESTA EJ

ACTH-induced Caveolin-1 Tyrosine Phosphorylation is Related to Podosome Assembly in Y1 Adrenal Cells.

EXPERIMENTAL CELL RESEARCH; Lugar: United States; Año: 2004 vol. 304 p. 432 - 442

BEY P, GOROSTIZAGA AB, MALOBERTI PM, LOZANO RC, PODEROSO C, CORNEJO MACIEL F, PODESTÁ EJ, PAZ C.

Adrenocorticotropin induces mitogen-activated protein kinase phosphatase 1 in Y1 mouse adrenocortical tumor cells.

ENDOCRINOLOGY; Año: 2003 p. 1309 - 1406

LOZANO RC, MALOBERTI P, MENDEZ CF, PAZ C, PODESTÁ EJ.

ACTH regulation of mitochondrial acyl-CoA thioesterase activity in Y1 adrenocortical tumour cells.

ENDOCRINE RESEARCH; Año: 2002 p. 331 - 337

PODEROSO C, PAZ C, GOROSTIZAGA A, CORNEJO MACIEL F, MENDEZ CF, PODESTA EJ.

Protein serine/threonine phosphatase 2A activity is inhibited by cAMP in MA-10 cells.

ENDOCRINE RESEARCH; Año: 2002 p. 319 - 323

MALOBERTI P, LOZANO RC, MELE PG, CANO F, COLONNA C, MENDEZ CF, PAZ C, PODESTÁ EJ.

Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells.

EUROPEAN JOURNAL OF BIOCHEMISTRY; Año: 2002 p. 5599 - 5607

SOLANO AR, DOURISBOURE RJ, WEITZEL J, PODESTA EJ.

A cautionary note: false homozygosity for BRCA2 6174delT mutation resulting from a single nucleotide polymorphism masking the wt allele.

EUROPEAN JOURNAL OF HUMAN GENETICS; Año: 2002 p. 395 - 397

CYMERYNG CB, LOTITO SP, COLONNA C, FINKIELSTEIN C, POMERANIEC Y, GRIÓN N, GADDA L, MALOBERTI P, PODESTÁ EJ.

Expression of nitric oxide synthases in rat adrenal zona fasciculata cells.

ENDOCRINOLOGY; Año: 2002 p. 1235 - 1242

PODEROSO C, CORNEJO MACIEL F, GOROSTIZAGA A, BEY P, PAZ C, PODESTÁ EJ.

The obligatory action of protein tyrosine phosphatases in ACTH-stimulated steroidogenesis is exerted at the level of StAR protein.

ENDOCRINE RESEARCH; Año: 2002 p. 413 - 417

NEUMAN I, MALOBERTI P, LISDERO C, COLONNA C, PERALTA J, JOSÉ JP, PODESTÁ EJ.

beta-Adrenergic stimulation controls the expression of a thioesterase specific for very-long-chain fatty acids in perfused hearts.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 2002 p. 135 - 141

PAZ C1, CORNEJO MACIEL F, MALOBERTI P, WALSH LP, STOCCO DM, PODESTÁ EJ.

Protein tyrosine phosphatases are involved in LH/chorionic gonadotropin and 8Br-cAMP regulation of steroidogenesis and StAR protein levels in MA-10 Leydig cells.

JOURNAL OF MOLECULAR ENDOCRINOLOGY; Año: 2002 p. 793 - 801

ERRASTI AE, REY-ARES V, DARAY FM, ROGINES-VELO MP, SARDI SP, PAZ C, PODESTÁ EJ, ROTHLIN RP.

Human umbilical vein: involvement of cyclooxygenase-2 pathway in bradykinin B1 receptor-sensitized responses.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY; Lugar: Berlin; Año: 2001 p. 149 - 156

CORNEJO MACIEL F, PODEROSO C, GOROSTIZAGA A, PAZ C, PODESTÁ EJ.

LH/chorionic gonadotropin signaling pathway involves protein tyrosine phosphatase activity downstream of protein kinase A activation: evidence of an obligatory step in steroid production by Leydig cells.

JOURNAL OF ENDOCRINOLOGY; Año: 2001 p. 403 - 411

MALOBERTI P, MELE PG, NEUMAN I, CORNEJO MACIEL F, CANO F, BEY P, PAZ C, PODESTÁ EJ.

Regulation of arachidonic acid release in steroidogenesis: role of a new acyl-CoA thioestrase (ARTISt).

ENDOCRINE RESEARCH; Año: 2000 p. 653 - 662

PAZ C, CORNEJO MACIEL F, PODEROSO C, GOROSTIZAGA A, PODESTÁ EJ.

An ACTH-activated protein tyrosine phosphatase (PTP) is modulated by PKA-mediated phosphorylation.

ENDOCRINE RESEARCH; Año: 2000 p. 609 - 614

CYMERYNG CB, LOTITO SP, COLONNA C, CORNEJO MF, PODESTÁ EJ.

Induction of nitric oxide synthase activity in adrenal cells.

ENDOCRINE RESEARCH; Año: 2000 p. 589 - 595

NEUMAN I, LISDERO C, FINKIELSTEIN C, MALOBERTI P, MENDEZ CF, PODEROSO JJ, PODESTÁ EJ

Activation of a thioesterase specific for very-long-chain fatty acids by adrenergic agonists in perfused hearts.

BIOCHIMICA AND BIOPHYSICA ACTA; Año: 1999 p. 101 - 108

CYMERYNG CB, DADA LA, COLONNA C, MENDEZ CF, PODESTÁ EJ.

Effects of L-arginine in rat adrenal cells: involvement of nitric oxide synthase.

ENDOCRINOLOGY; Año: 1999 p. 2962 - 2967

PAZ C, CORNEJO MACIEL F, MENDEZ C, PODESTA EJ.

Corticotropin increases protein tyrosine phosphatase activity by a cAMP-dependent mechanism in rat adrenal gland.

EUROPEAN JOURNAL OF BIOCHEMISTRY; Año: 1999 p. 911 - 918

FINKIELSTEIN CV, MALOBERTI P, MENDEZ CF, PODESTÁ EJ.

A novel arachidonic acid-related thioesterase involved in acute steroidogenesis.

ENDOCRINE RESEARCH; Año: 1998 p. 363 - 371

FINKIELSTEIN C, MALOBERTI P, MENDEZ CF, PAZ C, CORNEJO MACIEL F, CYMERYNG C, NEUMAN I, DADA L, MELE PG, SOLANO A, PODESTÁ EJ.

An adrenocorticotropin-regulated phosphoprotein intermediary in steroid synthesis is similar to an acyl-CoA thioesterase enzyme.

EUROPEAN JOURNAL OF BIOCHEMISTRY; Año: 1998 p. 60 - 66

CYMERYNG CB, DADA LA, PODESTÁ EJ.

Effect of nitric oxide on rat adrenal zona fasciculata steroidogenesis.

JOURNAL OF ENDOCRINOLOGY; Año: 1998 p. 197 - 203

CORNEJO MACIEL F, PAZ C, NEUMAN MI, PODESTÁ EJ.

Phosphotyrosine protein phosphatases activation by ACTH in rat adrenal gland.

ENDOCRINE RESEARCH; Año: 1998 p. 381 - 386

MELE PG, DADA LA, PAZ C, NEUMAN I, CYMERYNG CB, MENDEZ CF, FINKIELSTEIN CV, CORNEJO MACIEL F, PODESTÁ EJ.

Involvement of arachidonic acid and the lipoxygenase pathway in mediating luteinizing hormone-induced testosterone synthesis in rat Leydig cells.

ENDOCRINE RESEARCH; Año: 1997 p. 15 - 26

FINKIELSTEIN C, CYMERYNG C, PAZ C, NEUMAN I, DADA L, CORNEJO MACIEL F, MELE PG, MENDEZ CF, MALOBERTI P, SOLANO AR, SCHIMMER BP, PODESTÁ EJ.

Characterization of the cDNA corresponding to a phosphoprotein (p43) intermediary in the action of ACTH.

ENDOCRINE RESEARCH; Año: 1996 p. 521 - 532

MELE PG, DADA LA, PAZ C, CYMERYNG CB, CORNEJO MACIEL MF, NEUMAN MI, FINKIELSTEIN CV, MENDEZ CF, PODESTÁ EJ.

Site of action of proteinases in the activation of steroidogenesis in rat adrenal gland.

BIOCHIMICA AND BIOPHYSICA ACTA; Año: 1996 p. 260 - 268

DADA L, CORNEJO MACIEL F, NEUMAN I, MELE PG, MALOBERTI P, PAZ C, CYMERYNG C, FINKIELSTEIN C, MENDEZ CF, PODESTÁ EJ.

Cytosolic and mitochondrial proteins as possible targets of cycloheximide effect on adrenal steroidogenesis.

ENDOCRINE RESEARCH; Año: 1996 p. 533 - 539

BRIGNONI M, PODESTA EJ, MELE P, RODRIGUEZ ML, VEGA-SALAS DE, SALAS PJ.

Exocytosis of vacuolar apical compartment (VAC) in Madin-Darby canine kidney epithelial cells: cAMP is involved as second messenger.

EXPERIMENTAL CELL RESEARCH; Año: 1993 p. 171 - 178

DADA LA, PAZ C, MELE P, SOLANO AR, CORNEJO MACIEL F, PODESTA EJ.

The cytosol as site of phosphorylation of the cyclic AMP-dependent protein kinase in adrenal steroidogenesis.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY; Año: 1991 p. 889 - 896

PODESTA EJ, SOLANO AR, LEMOS JR.

Stimulation of an individual cell with peptide hormone in a prescribed region of its plasma membrane results in a compartmentalized cyclic AMP-dependent protein kinase response.

JOURNAL OF MOLECULAR ENDOCRINOLOGY; Año: 1991 p. 269 - 279

NEUMAN I, SOLANO AR, PAZ C, MELE P, CORNEJO MACIEL F, LEMOS JR, FERNANDEZ HN, PODESTA EJ.

The action of luteinizing hormone on the testis.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY; Año: 1991 p. 441 - 451

SARDAÑONS ML, DE LAS HERAS MA, CALANDRA RS, SOLANO AR, PODESTÁ EJ.

Effect of the antiandrogen flutamide on pituitary LH content and release.

NEUROENDOCRINOLOGY; Año: 1989 p. 211 - 216

SOLANO AR, DADA L, PODESTA EJ.

Lipoxygenase products as common intermediates in cyclic AMP-dependent and -independent adrenal steroidogenesis in rats.

JOURNAL OF MOLECULAR ENDOCRINOLOGY; Año: 1988 p. 147 - 154

SOLANO AR, CREMASCHI G, SÁNCHEZ ML, BORDA E, STERIN-BORDA L, PODESTÁ EJ

Molecular and biological interaction between major histocompatibility complex class I antigens and luteinizing hormone receptors or beta-adrenergic receptors triggers cellular response in mice.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 1988 p. 5087 - 5091

SOLANO AR, SANCHEZ ML, SARDANONS ML, DADA L, PODESTÁ EJ.

Luteinizing hormone triggers a molecular association between its receptor and the major histocompatibility complex class I antigen to produce cell activation.

ENDOCRINOLOGY; Año: 1988 p. 2080 - 2083

SARDAÑONS ML, SOLANO AR, PODESTÁ EJ.

Gonadotropin-releasing hormone action upon luteinizing hormone bioactivity in pituitary gland: role of sulfation.

JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 1987 p. 149 - 155

SOLANO AR, SÁNCHEZ ML, PODESTÁ EJ, TURYN D, DELLACHA JM.

Membrane methylation in isolated rat testis interstitial cells unmasks functional luteinizing hormone receptors.

BIOCHIMICA AND BIOPHYSICA ACTA; Año: 1987 p. 107 - 113

SOLANO AR, DADA LA, LUZ SARDAÑONS M, SÁNCHEZ ML, PODESTÁ EJ.

Leukotrienes as common intermediates in the cyclic AMP dependent and independent pathways in adrenal steroidogenesis.

Journal of steroid biochemistry.; Año: 1987 p. 745 - 751

PODESTÁ EJ, SOLANO AR, SÁNCHEZ ML.

Luteinizing hormone triggers two opposite regulatory pathways through an initial common event, receptor aggregation.

ENDOCRINOLOGY; Año: 1986 p. 989 - 997

PODESTÁ EJ, SOLANO AR, MOLINA Y VEDIA L, PALADINI A JR, SÁNCHEZ ML, TORRES HN.

Production of steroid hormone and cyclic AMP in hybrids of adrenal and Leydig cells generated by electrofusion.

EUROPEAN JOURNAL OF BIOCHEMISTRY; Año: 1984 p. 329 - 332

SOLANO AR, NEHER R, PODESTA EJ.

Rat adrenal cycloheximide-sensitive factors and phospholipids in the control of acute steroidogenesis.

Journal of steroid biochemistry; Año: 1984 p. 111 - 116

PODESTÁ EJ, SOLANO AR, ATTAR R, SÁNCHEZ ML, MOLINA Y VEDIA L

Receptor aggregation induced by antilutropin receptor antibody and biological response in rat testis Leydig cells.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 1983 p. 86 - 90

NEHER R, MILANI A, SOLANO AR, PODESTÀ EJ.

Compartmentalization of corticotropin-dependent steroidogenic factors in adrenal cortex: evidence for a post-translational cascade in stimulation of the cholesterol side-chain split.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 1982 p. 27 - 31

PODESTA EJ, MILANI A, STEFFEN H, NEHER R.

Steroidogenic action of calcium ions in isolated adrenocortical cells.

BIOCHEMICAL JOURNAL; Año: 1980 p. 391 - 397

PODESTA EJ, MILANI A, STEFFEN H, NEHER R.

Adrenocorticotropin (ACTH) induces phosphorylation of a cytoplasmic protein in intact isolated adrenocortical cells.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 1979 p. 355 - 363

PODESTA EJ, DUFAU ML, SOLANO AR, CATT KJ.

Hormonal activation of protein kinase in isolated Leydig cells. Electrophoretic analysis of cyclic AMP receptors.

JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 1978 p. 8994 - 9001

PODESTA EJ, DUFAU ML, CATT KJ.

Cyclic adenosine 3',5'-monophosphate dependent protein kinase of rat Leydig cells: physical characteristics of two holoenzymes and their subunits.

BIOCHEMISTRY; Lugar: Washington; Año: 1978 p. 1566 - 1573

DUFAU ML, TSURUHARA T, HORNER KA, PODESTA E, CATT KJ.

Intermediate role of adenosine 3':5'-cyclic monophosphate and protein kinase during gonadotropin-induced steroidogenesis in testicular interstitial cells.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 1977 p. 3419 - 3423

CIGORRAGA S, PODESTÁ EJ, CHEMES HE, RIVAROLA MA, CHARREAU EH.

Metabolism of testosterone and dihydrotestosterone in subcellular fractions of seminiferous tubules at the time of initiation of the meiotic division.

Journal of steroid biochemistry; Año: 1977 p. 747 - 752

PODESTA EJ, DUFAU ML, CATT KJ.

Adenosine 3',5'-monophosphate-dependent protein kinase of Leydig cells: in vitro activation and relationship to gonadotropin action upon cyclic AMP and steroidogenesis.

FEBS LETTERS; Lugar: Amsterdam; Año: 1976 p. 212 - 216

PODESTA EJ, DUFAU ML, CATT KJ.

Characterization of two forms of cyclic 3', 5'-adenosine monophosphate-dependent protein kinase in rat testicular interstitial cells.

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Lugar: Amsterdam; Año: 1976 p. 109 - 122

CHEMES HE, PODESTA E, RIVAROLA MA.

Action of testosterone, dihydrotestosterone and 5alpha androstane 3alpha, 17beta diol on the spermatogenesis of immature rats.

BIOLOGY OF REPRODUCTION; Año: 1976 p. 332 - 338

PODESTÁ EJ, CALANDRA RS, RIVAROLA MA, BLAQUIER JA.

The effect of castration and testosterone replacement on specific proteins and androgen levels of the rat epididymis.

ENDOCRINOLOGY; Año: 1975 p. 399 - 405

DUFAU ML, PODESTA EJ, CATT KJ.

Physical characteristics of the gonadotropin receptor-hormone complexes formed in vivo and in vitro.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 1975 p. 1272 - 1275

RIVAROLA MA, PODESTÁ EJ, CHEMES HE, CALANDRA RS

Androgen metabolism and concentration in the seminiferous tubules at different stages of development.

Journal of steroid biochemistry; Año: 1975 p. 365 - 369

RIVAROLA MA, PODESTA EJ, CHEMES HE, CIGORRAGA S.

Androgen metabolism in the seminiferous tubule.

Current topics in molecular endocrinology; Año: 1975 p. 25 - 35

CALANDRA RS, PODESTÁ EJ, RIVAROLA MA, BLAQUIER JA.

Tissue androgens and androphilic proteins in rat epididymis during sexual development.

STEROIDS; Lugar: Amsterdam; Año: 1974 p. 507 - 518

PODESTÁ EJ, RIVAROLA MA.

Concentration of androgens in whole testis, seminiferous tubules and interstitial tissue of rats at different stages of development.

ENDOCRINOLOGY; Año: 1974 p. 455 - 461

RIVAROLA MA, PODESTÁ EJ, CHEMES HE.

Proceedings: Androgen metabolism in the seminiferous tubules.

Acta physiologica latino americana; Año: 1973 p. 594 - 596

RIVAROLO MA, PODESTA EJ, CHEMES HE.

In vitro testosterone-14C metabolism by rat seminiferous tubules at different stages of development: formation of -androstandiol at meiosis.

ENDOCRINOLOGY; Año: 1972 p. 537 - 542

RIVAROLA MA, HEINRICH JJ, PODESTÁ EJ, DE CHWOJNIK MF, BERGADÁ C.

Testicular function in hypopituitarism.

PEDIATRIC RESEARCH; Año: 1972 p. 634 - 640

RIVAROLA MA, PODESTÁ EJ.

Metabolism of testosterone-14C by seminiferous tubules of mature rats: formation of 5 alpha-androstan-3 alpha-17 beta-14C.

ENDOCRINOLOGY; Año: 1972 p. 618 - 623