PIROLA, CARLOS JOSE; SALATINO, ADRIAN; FERNÁNDEZ GIANOTTI, TOMAS; CASTAÑO, GUSTAVO OSVALDO; GARAYCOECHEA, MARTIN; SOOKOIAN, SILVIA

Cross talk between the liver microbiome and epigenome in patients with metabolic dysfunction-associated steatotic liver disease

eBioMedicine; Lugar: Amsterdam; Año: 2024 vol. 101 p. 104996 - 105017

PIROLA, CARLOS JOSE; SOOKOIAN, SILVIA

The gene expression signature of metabolic dysfunction- associated steatotic liver disease from a multiomics perspective

Clinical and Molecular Hepatology; Lugar: Seul; Año: 2024 vol. 30 p. 174 - 176

ÅBERG, FREDRIK; BYRNE, CHRISTOPHER D.; PIROLA, CARLOS J.; MÄNNISTÖ, VILLE; SOOKOIAN, SILVIA

Alcohol consumption and metabolic syndrome: Clinical and epidemiological impact on liver disease

JOURNAL OF HEPATOLOGY; Año: 2023 vol. 78 p. 191 - 206

VALLI, EDUARDO; DALOTTO?MORENO, TOMÁS; STERLE, HELENA A.; MÉNDEZ?HUERGO, SANTIAGO P.; PAULAZO, MARÍA A.; GARCÍA, SILVIA I.; PIROLA, CARLOS J.; KLECHA, ALICIA J.; RABINOVICH, GABRIEL A.; CREMASCHI, GRACIELA A.

Hypothyroidism‐associated immunosuppression involves induction of galectin‐1‐producing regulatory T cells

FASEB JOURNAL; Año: 2023 vol. 37 p. 1 - 16

PIROLA, CARLOS J.; SOOKOIAN, SILVIA

SARS-CoV-2 targets the liver and manipulates glucose metabolism

TRENDS IN MOLECULAR MEDICINE; Año: 2023 vol. 29 p. 681 - 683

SOOKOIAN, SILVIA; PIROLA, CARLOS J.

Genetics in non-alcoholic fatty liver disease: The role of risk alleles through the lens of immune response

Clinical and Molecular Hepatology; Lugar: Seoul; Año: 2023 vol. 29 p. 184 - 195

PIROLA, CARLOS J.; SOOKOIAN, SILVIA

COVID-19 and non-alcoholic fatty liver disease: Biological insights from multi-omics data

LIVER INTERNATIONAL; Año: 2023 vol. 43 p. 580 - 587

PIROLA CJ; SOOKOIAN S

Editorial: NAFLD, chronic kidney disease, and pleiotropy-Why is PNPLA3 omnipresent?

ALIMENTARY PHARMACOLOGY & THERAPEUTICS.; Lugar: Londres; Año: 2023 vol. 57 p. 1180 - 1182

PIROLA, CARLOS J; SOOKOIAN, SILVIA

Advances in our understanding of the molecular heterogeneity of fatty liver disease: toward informed treatment decision making

Expert Review of Gastroenterology and Hepatology; Lugar: Abingdon, Oxford; Año: 2023 vol. 17 p. 317 - 324

PIROLA, CARLOS J.; SOOKOIAN, SILVIA

Non-alcoholic fatty liver disease mediates the effect of obesity on arterial hypertension

LIVER INTERNATIONAL; Año: 2023 vol. 43 p. 2167 - 2176

SOOKOIAN, SILVIA; PIROLA, CARLOS J.

The serum uric acid/creatinine ratio is associated with nonalcoholic fatty liver disease in the general population

JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY; Lugar: Navarra; Año: 2023 vol. 79 p. 891 - 899

SALATINO, ADRIAN; SOOKOIAN, SILVIA; PIROLA, CARLOS J.

Computational Pipeline for Next-Generation Sequencing (NGS) Studies in Genetics of NASH

METHODS IN MOLECULAR BIOLOGY (CLIFTON, N.J.); Lugar: New York, NY; Año: 2022 vol. 2455 p. 203 - 222

PIROLA, CARLOS JOSE; SALATINO, ADRIAN; QUINTANILLA, MARIA FLORENCIA; CASTAÑO, GUSTAVO OSVALDO; GARAYCOECHEA, MARTIN; SOOKOIAN, SILVIA

The influence of host genetics on liver microbiome composition in patients with NAFLD

eBioMedicine; Lugar: Amsterdam; Año: 2022 vol. 76 p. 103858 - 103871

PIROLA, CARLOS J.; SOOKOIAN, SILVIA

Metabolic dysfunction-associated fatty liver disease: advances in genetic and epigenetic implications

CURRENT OPINION IN LIPIDOLOGY; Lugar: Philadelphia; Año: 2022 vol. 33 p. 95 - 102

PIROLA, CARLOS J.; SOOKOIAN, SILVIA

MicroRNAs as messengers of liver diseases: has the message finally been decrypted?

CLINICAL SCIENCE (LONDON, ENGLAND : 1979); Lugar: Londres; Año: 2022 vol. 136 p. 323 - 328

DIAMBRA L.; ALONSO A.M.; SOOKOIAN S.; PIROLA, C. J.

Single cell gene expression profiling of nasal ciliated cells reveals distinctive biological processes related to epigenetic mechanisms in patients with severe COVID-19

COMPUTERS IN BIOLOGY AND MEDICINE; Lugar: Amsterdam; Año: 2022 vol. 148

VILAR-GOMEZ, EDUARDO; PIROLA, CARLOS J.; SOOKOIAN, SILVIA; WILSON, LAURA A.; LIANG, TIEBING; CHALASANI, NAGA

PNPLA3 rs738409 and risk of fibrosis in NAFLD: Exploring mediation pathways through intermediate histological features

HEPATOLOGY (BALTIMORE, MD.); Lugar: Hoboken, NJ; Año: 2022 vol. 76 p. 1482 - 1494

PIROLA CJ; SOOKOIAN S

Personalized Medicine in Nonalcoholic Fatty Liver Disease

Clinical and Molecular Hepatology; Lugar: Seoul; Año: 2022 vol. 28 p. 935 - 938

PIROLA, CARLOS J.; SILVIA SOOKOIAN

Repurposing drugs to target nonalcoholic steatohepatitis: Auranofin, a gold-organic molecule complex for the treatment of a specifc complex trait.

Clinical and Molecular Hepatology; Lugar: Seoul; Año: 2022 vol. 28 p. 806 - 809

SOOKOIAN, SILVIA; PIROLA, CARLOS J.

Liver tissue microbiota in nonalcoholic liver disease: a change in the paradigm of host-bacterial interactions

Hepatobiliary Surgery and Nutrition; Lugar: Hong Kong; Año: 2021 vol. 10 p. 337 - 349

PIROLA, CARLOS J.; SOOKOIAN, SILVIA

The lipidome in nonalcoholic fatty liver disease: actionable targets

JLR PAPERS IN PRESS; Año: 2021 vol. 62 p. 1 - 15

PIROLA, CARLOS J.; SOOKOIAN, SILVIA

PNPLA3 and COVID-19 outcomes: Thinking outside the box might explain the biology behind pleiotropic effects of rs738409 on the immune system

LIVER INTERNATIONAL; Lugar: Londres; Año: 2021 vol. 41 p. 2081 - 2804

PIROLA, CARLOS J; GARAYCOECHEA, MARTIN; FLICHMAN, DIEGO; CASTAÑO, GUSTAVO O; SOOKOIAN, SILVIA

Liver mitochondrial DNA damage and genetic variability of Cytochrome b ‐ a key component of the respirasome ‐ drive the severity of fatty liver disease

JOURNAL OF INTERNAL MEDICINE; Año: 2021 vol. 289 p. 84 - 96

PIROLA, CARLOS J; SOOKOIAN, SILVIA

NAFLD and cardiometabolic risk factors: The liver fibrosis trajectory through the lens of biological interactions

HEPATOLOGY (BALTIMORE, MD.); Lugar: Baltimore; Año: 2021 vol. 73 p. 479 - 482

PIROLA, CARLOS JOSE; SALATINO, ADRIAN; SOOKOIAN, SILVIA

Pleiotropy within gene variants associated with nonalcoholic fatty liver disease and traits of the hematopoietic system

WORLD JOURNAL OF GASTROENTEROLOGY; Lugar: Beijing; Año: 2021 vol. 27 p. 305 - 320

PIROLA, CARLOS J.; SOOKOIAN, SILVIA

Editorial: bariatric surgery to reduce the risk of liver cancer

ALIMENTARY PHARMACOLOGY & THERAPEUTICS.; Año: 2021 vol. 53 p. 1155 - 1156

VILAR-GOMEZ, EDUARDO; PIROLA, CARLOS J.; SOOKOIAN, SILVIA; WILSON, LAURA A.; BELT, PATRICIA; LIANG, TIEBING; LIU, WANQING; CHALASANI, NAGA

Impact of the Association Between PNPLA3 Genetic Variation and Dietary Intake on the Risk of Significant Fibrosis in Patients With NAFLD

AMERICAN JOURNAL OF GASTROENTEROLOGY; Año: 2021 vol. 116 p. 994 - 1006

VILAR-GOMEZ, EDUARDO; PIROLA, CARLOS J.; SOOKOIAN, SILVIA; WILSON, LAURA A.; LIANG, TIEBING; CHALASANI, NAGA

The Protection Conferred by HSD17B13 rs72613567 Polymorphism on Risk of Steatohepatitis and Fibrosis May Be Limited to Selected Subgroups of Patients With NAFLD

Clinical and Translational Gastroenterology; Lugar: New York; Año: 2021 vol. 12 p. 400 - 412

SOOKOIAN, SILVIA; PIROLA, CARLOS J.

Precision medicine in nonalcoholic fatty liver disease: New therapeutic insights from genetics and systems biology

Clinical and Molecular Hepatology; Lugar: Seul; Año: 2020 vol. 26 p. 461 - 475

PIROLA, CARLOS J.; SOOKOIAN, SILVIA

SARS‐CoV‐2 virus and liver expression of host receptors: Putative mechanisms of liver involvement in COVID‐19

LIVER INTERNATIONAL; Año: 2020 vol. 40 p. 2038 - 2040

SOOKOIAN, SILVIA; PIROLA, CARLOS J.; VALENTI, LUCA; DAVIDSON, NICHOLAS O.

Genetic pathways in nonalcoholic fatty liver disease: Insights from systems biology

HEPATOLOGY (BALTIMORE, MD.); Lugar: New York; Año: 2020 vol. 72 p. 330 - 346

PIROLA, CARLOS JOSE; SOOKOIAN, SILVIA

Epigenetics factors in nonalcoholic fatty liver disease

Expert Review of Gastroenterology & Hepatology; Lugar: Londres; Año: 2020 p. 1 - 16

LANDA, MARÍA SILVINA; GARCÍA, SILVIA INÉS; SCHUMAN, MARIANO LUIS; PERES DIAZ, LUDMILA SOLEDAD; AISICOVICH, MAIA; PIROLA, CARLOS JOSÉ

Cardiovascular and body weight regulation changes in transgenic mice overexpressing thyrotropin-releasing hormone (TRH)

JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY; Lugar: Navarra; Año: 2020 vol. 76 p. 599 - 608

SOOKOIAN, SILVIA; SALATINO, ADRIAN; CASTAÑO, GUSTAVO OSVALDO; LANDA, MARIA SILVIA; FIJALKOWKY, CINTHIA; GARAYCOECHEA, MARTIN; PIROLA, CARLOS JOSE

Intrahepatic bacterial metataxonomic signature in non-alcoholic fatty liver disease

GUT - AN INTERNATIONAL JOURNAL OF GASTROENTEOROLOGY AND HEPATOLOGY; Año: 2020 vol. 69 p. 1483 - 1491

PIROLA, CARLOS J.; SOOKOIAN, SILVIA

Estimation of RAAS-Inhibitor effect on the COVID-19 outcome: A Meta-analysis

THE JOURNAL OF INFECTION.; Año: 2020 vol. 81 p. 276 - 281

PIROLA, CARLOS J.; SOOKOIAN, SILVIA

COVID-19 and ACE2 in the liver and gastrointestinal tract: Putative biological explanations of sexual dimorphism

GASTROENTEROLOGY; Lugar: Baltimore; Año: 2020 vol. 159 p. 1620 - 1621

VILAR-GOMEZ, EDUARDO; SOOKOIAN, SILVIA; PIROLA, CARLOS JOSE; LIANG, TIEBING; GAWRIEH, SAMER; CUMMINGS, OSCAR; LIU, WANQING; CHALASANI, NAGA P.

ADH1B∗2 Is Associated With Reduced Severity of Nonalcoholic Fatty Liver Disease in Adults, Independent of Alcohol Consumption

GASTROENTEROLOGY; Año: 2020 vol. 159 p. 929 - 943

PERES DIAZ, LUDMILA SOLEDAD; SCHUMAN, MARIANO LUIS; AISICOVICH, MAIA; TOBLLI, JORGE EDUARDO; PIROLA, CARLOS JOSÉ; LANDA, MARÍA SILVINA; GARCÍA, SILVIA INÉS

Short-term doxorubicin cardiotoxic effects: involvement of cardiac Thyrotropin Releasing Hormone system

LIFE SCIENCES; Año: 2020 vol. 261

PIROLA, CARLOS J; SOOKOIAN, SILVIA

Age but not sex may explain the negative effect of arterial hypertension and diabetes on COVID-19 prognosis

THE JOURNAL OF INFECTION.; Año: 2020 vol. 81 p. 647 - 679

VILAR-GOMEZ, EDUARDO; PIROLA, CARLOS J; SOOKOIAN, SILVIA; WILSON, LAURA A.; BELT, PATRICIA; LIANG, TIEBING; LIU, WANQING; CHALASANI, NAGA

Impact of the Association Between PNPLA3 Genetic Variation and Dietary Intake on the Risk of Significant Fibrosis in Patients With NAFLD

AMERICAN JOURNAL OF GASTROENTEROLOGY; Año: 2020 vol. 116 p. 994 - 1006

SOOKOIAN, SILVIA; PIROLA, CARLOS J

Genetics of Nonalcoholic Fatty Liver Disease: From Pathogenesis to Therapeutics

SEMINARS IN LIVER DISEASE; Año: 2019

SOOKOIAN, SILVIA; PIROLA, CARLOS J.

Review article: shared disease mechanisms between non-alcoholic fatty liver disease and metabolic syndrome – translating knowledge from systems biology to the bedside

ALIMENTARY PHARMACOLOGY & THERAPEUTICS.; Año: 2019 vol. 49 p. 516 - 527

SOOKOIAN, S.; PIROLA, CARLOS J.

Nonalcoholic steatohepatitis pharmacotherapy and predictors of response: dual role of aminotransferases as biosensors of metabolism and biomarkers of histological improvement.

Hepatobiliary Surg Nutr; Lugar: Hong Kong; Año: 2019 vol. 8 p. 381 - 385

PIROLA, CARLOS J.; GARAYCOECHEA, MARTIN; FLICHMAN, DIEGO; ARRESE, MARCO; SAN MARTINO, JULIO; GAZZI, CARLA; CASTAÑO, GUSTAVO O.; SOOKOIAN, SILVIA

Splice variant rs72613567 prevents worst histologic outcomes in patients with nonalcoholic fatty liver disease

JLR PAPERS IN PRESS; Año: 2019 vol. 60 p. 176 - 185

SOOKOIAN, SILVIA; ARRESE, MARCO; PIROLA, CARLOS J.

Genetics Meets Therapy? Exome-wide Association Study Reveals a Loss-of-Function Variant in 17-Beta-Hydroxysteroid Dehydrogenase 13 That Protects Patients From Liver Damage and Nonalcoholic Fatty Liver Disease Progression

HEPATOLOGY (BALTIMORE, MD.); Lugar: Hoboken, NJ; Año: 2019 vol. 69 p. 907 - 910

SOOKOIAN, SILVIA; PIROLA, CARLOS J.

Repurposing drugs to target nonalcoholic steatohepatitis

WORLD JOURNAL OF GASTROENTEROLOGY; Lugar: Beijing; Año: 2019 vol. 25 p. 1783 - 1796

SOOKOIAN, SILVIA; FLICHMAN, DIEGO; GARAYCOECHEA, MARTIN E.; GAZZI, CARLA; MARTINO, JULIO SAN; CASTAÑO, GUSTAVO O.; PIROLA, CARLOS J.

Lack of evidence supporting a role of TMC4-rs641738 missense variant—MBOAT7- intergenic downstream variant—in the Susceptibility to Nonalcoholic Fatty Liver Disease

Scientific Reports; Lugar: London; Año: 2018 vol. 8 p. 5097 - 5108

CARLOS J. PIROLA; SILVIA SOOKOIAN

Tackling the complexity of nonalcoholic steatohepatitis treatment: challenges and opportunities based on systems biology and machine learning approaches.

Hepatobiliary Surgery and Nutrition; Lugar: Hong Kong; Año: 2018 vol. 7 p. 495 - 498

SOOKOIAN, SILVIA; FLICHMAN, DIEGO; GARAYCOECHEA, MARTIN E.; SAN MARTINO, JULIO; CASTAÑO, GUSTAVO O.; PIROLA, CARLOS J.

Metastasis-associated lung adenocarcinoma transcript 1 as a common molecular driver in the pathogenesis of nonalcoholic steatohepatitis and chronic immune-mediated liver damage

Hepatology Communications; Lugar: Hoboken, NJ; Año: 2018

SOOKOIAN, S.; PIROLA, C.J.

Systematic review with meta-analysis: The significance of histological disease severity in lean patients with nonalcoholic fatty liver disease

ALIMENTARY PHARMACOLOGY & THERAPEUTICS.; Año: 2018 vol. 47 p. 16 - 25

SOOKOIAN, SILVIA; PIROLA, CARLOS J.

Nonalcoholic Fatty Liver Disease Progresses into Severe NASH when Physiological Mechanisms of Tissue Homeostasis Collapse

ANNALS OF HEPATOLOGY; Año: 2018 vol. 17 p. 182 - 186

SOOKOIAN, SILVIA; PIROLA, CARLOS J.

The nonalcoholic steatohepatitis metabotype: Imbalance of circulating amino acids and transamination reactions reflect impaired mitochondrial function

HEPATOLOGY (BALTIMORE, MD.); Lugar: Hoboken; Año: 2018 vol. 67 p. 1177 - 1178

PIROLA, CARLOS J; SOOKOIAN, SILVIA

Multiomics biomarkers for the prediction of nonalcoholic fatty liver disease severity

WORLD JOURNAL OF GASTROENTEROLOGY; Lugar: Beijing; Año: 2018 vol. 24 p. 1601 - 1615

PIROLA, C. J.; SOOKOIAN, S.

Editorial: surviving your genes-the role of PNPLA3 variation in end-stage liver disease

ALIMENTARY PHARMACOLOGY & THERAPEUTICS.; Año: 2018 vol. 48 p. 773 - 775

PIROLA, CARLOS J.; FLICHMAN, DIEGO; DOPAZO, HERNÁN; FERNÁNDEZ GIANOTTI, TOMAS; SAN MARTINO, JULIO; ROHR, CRISTIAN; GARAYCOECHEA, MARTIN; GAZZI, CARLA; CASTAÑO, GUSTAVO O.; SOOKOIAN, SILVIA

A Rare Nonsense Mutation in the Glucokinase Regulator Gene Is Associated With a Rapidly Progressive Clinical Form of Nonalcoholic Steatohepatitis

Hepatology Communications; Año: 2018 vol. 2 p. 1082 - 1088

PERES DIAZ, LUDMILA S.; SCHUMAN, MARIANO LUIS; AISICOVICH, MAIA; TOBLLI, JORGE EDUARDO; PIROLA, CARLOS JOSÉ; LANDA, MARÍA SILVINA; GARCÍA, SILVIA INÉS

Angiotensin II requires an intact cardiac thyrotropin-releasing hormone (TRH) system to induce cardiac hypertrophy in mouse

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY; Año: 2018 vol. 124 p. 1 - 11

SILVIA SOOKOIAN; CARLOS J. PIROLA

Nonalcoholic fatty liver disease: Biomarkers support decisions around pharmacological intervention.

HEPATOLOGY (BALTIMORE, MD.); Lugar: New York; Año: 2017 vol. 65 p. 1417 - 1419

TELLECHEA, M.L.; PIROLA, C.J.

The impact of hypertension on leukocyte telomere length: a systematic review and meta-analysis of human studies.

JOURNAL OF HUMAN HYPERTENSION; Lugar: Londres; Año: 2017 vol. 31 p. 99 - 105

SILVIA SOOKOIAN; PUNEET PURI; GUSTAVO O CASTAÑO; ROMINA SCIAN; FARIDODDIN MIRSHASHI; ARUN SANYAL; CARLOS J. PIROLA

Nonalcoholic steatohepatitis is associated with a state of betaine-insufficiency.

LIVER INTERNATIONAL; Lugar: Londres; Año: 2017 vol. 37 p. 611 - 619

SILVIA SOOKOIAN; CARLOS J PIROLA

Genetic predisposition in nonalcoholic fatty liver disease.

Clinical and Molecular Hepatology; Lugar: Seoul; Año: 2017 vol. 23 p. 1 - 12

SOOKOIAN S.; ROHR, C; SALATINO A; DOPAZO, H; FERNANDEZ GIANOTTI T; CASTAÑO G,; PIROLA CJ

Genetic variation in long noncoding RNAs and the risk of nonalcoholic fatty liver disease.

Oncotarget; Lugar: Albany, N.Y. ; Año: 2017 vol. 8 p. 22917 - 22926

SILVIA SOOKOIAN; CARLOS J. PIROLA

Cell-free DNA methylation as liquid biopsy for the assessment of fibrosis in patients with nonalcoholic steatohepatitis: a gap between innovation and implementation.

HepatoBiliary Surgery and Nutrition; Lugar: Hong Kong; Año: 2017 vol. 6 p. 117 - 121

CARLOS J. PIROLA; SILVIA SOOKOIAN

The natural history of nonalcoholic fatty liver disease: mortality rates and liver enzymes

Hepatobiliary Surgery and Nutrition; Lugar: Hong Kong; Año: 2017 vol. 62 p. 130 - 134

SOOKOIAN, S.; PIROLA, C. J.

Systematic review with meta-analysis: risk factors for non-alcoholic fatty liver disease suggest a shared altered metabolic and cardiovascular profile between lean and obese patients

ALIMENTARY PHARMACOLOGY & THERAPEUTICS.; Año: 2017 vol. 46 p. 85 - 95

TELLECHEA, MARIANA L.; MENSEGUE, MELISA F.; PIROLA, CARLOS J.

The Association between High Fat Diet around Gestation and Metabolic Syndrome-related Phenotypes in Rats: A Systematic Review and Meta-Analysis

Scientific Reports; Año: 2017 vol. 7

BONNET, GEMMA; GÓMEZ-ABELLÁN, PURIFICACIÓN; VERA, BEATRIZ; SÁNCHEZ-ROMERA, JUAN FRANCISCO; HERNÁNDEZ-MARTÍNEZ, ANTONIO M.; SOOKOIAN, SILVIA; PIROLA, CARLOS JOSE; GARAULET, MARTA

Serotonin-transporter promoter polymorphism modulates the ability to control food intake: effect on total weight loss

MOLECULAR NUTRITION & FOOD RESEARCH; Año: 2017

SOOKOIAN, SILVIA; PIROLA, CARLOS J.

The nonalcoholic steatohepatitis metabotype: Imbalance of circulating amino acids and transamination reactions reflect impaired mitochondrial function

HEPATOLOGY (BALTIMORE, MD.); Lugar: Hoboken, NJ; Año: 2017

SOOKOIAN S; FLICHMAN, D; SCIAN, R; ROHR, C; DOPAZO, H; FERNANDEZ GIANOTTI, T; SAN MARTINO J; CASTANO G; PIROLA CJ

. Mitochondrial genome architecture in non-alcoholic fatty liver disease

JOURNAL OF PATHOLOGY; Lugar: Londres; Año: 2016 vol. 240 p. 437 - 449

SILVIA SOOKOIAN; GUSTAVO O CASTAÑO; ROMINA SCIAN; JULIO SAN MARTINO; CARLOS J. PIROLA

Heat Shock Protein 27 is down-regulated in Ballooned Hepatocytes of Patients with Nonalcoholic Steatohepatitis (NASH)

Scientific Reports; Lugar: London; Año: 2016 vol. 6 p. 1 - 8

LONARDO A; SOOKOIAN S; PIROLA CJ; TARGHER G

Non-alcoholic fatty liver disease and risk of cardiovascular disease

METABOLISM-CLINICAL AND EXPERIMENTAL; Lugar: Philadelphia; Año: 2016 vol. 65 p. 1136 - 1150

SILVIA C. SOOKOIAN; DIEGO FLICHMAN; GUSTAVO O CASTAÑO; CARLOS J. PIROLA

Mendelian randomisation suggests no beneficial effect of moderate alcohol consumption on the severity of nonalcoholic fatty liver disease

ALIMENTARY PHARMACOLOGY & THERAPEUTICS.; Lugar: Londres; Año: 2016 vol. 44 p. 1224 - 1234

PIROLA CJ; SOOKOIAN S

The Modulation of Liver Methylome in Liver Diseases

JOURNAL OF HEPATOLOGY; Lugar: Amsterdam; Año: 2016 vol. 64 p. 987 - 988

SOOKOIAN, S.; CASTAÑO, G.; SCIAN, R; FERNANDEZ GIANOTTI, T; DOPAZO, H; ROHR, C; SAN MARTINO J; SEVIC, I; FLICHMAN, D; PIROLA, C.J.

Serum aminotransferases in nonalcoholic fatty liver disease are a signature of liver metabolic perturbations at the amino acid and Krebs cycle level.

AMERICAN JOURNAL OF CLINICAL NUTRITION; Lugar: Maryland, EE.UU.; Año: 2016 vol. 103 p. 422 - 434

YIN X; SUBRAMANIAN S; WILLINGER CM; CHEN G; JUHASZ P; COURCHESNE P; CHEN BH; LI X; HWANG SJ; FOX CS; O'DONNELL CJ; MUNTENDAM P; FUSTER V; BOBELDIJK-PASTOROVA I; SOOKOIAN SC; PIROLA CJ; GORDON N; ADOURIAN A; LARSON MG; LEVY D

Metabolite Signatures of Metabolic Risk Factors and their Longitudinal Changes.

JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM; Año: 2016 vol. 101 p. 1779 - 1789

SOOKOIAN S; PIROLA CJ

Elafibranor for the treatment of NAFLD: One pill, two molecular targets and multiple effects in a complex phenotype

ANNALS OF HEPATOLOGY; Lugar: Mexico, DF.; Año: 2016 vol. 15 p. 604 - 609

SILVIA SOOKOIAN; CARLOS J PIROLA

How safe is Moderate Alcohol Consumption in Overweight and Obese Individuals?

GASTROENTEROLOGY; Lugar: Philadelphia; Año: 2016 vol. 150 p. 1698 - 1703

SILVIA SOOKOIAN; CARLOS J. PIROLA

Meta-analysis of the influence of TM6SF2 E167K variant on Plasma Concentration of Aminotransferases across different Populations and Diverse Liver Phenotypes

Scientific Reports; Lugar: London; Año: 2016 vol. 6 p. 27718 - 27728

SILVIA SOOKOIAN; CARLOS JOSE PIROLA

Nonalcoholic fatty liver disease and metabolicsyndrome: Shared genetic basis of pathogenesis

HEPATOLOGY (BALTIMORE, MD.); Lugar: New York; Año: 2016 vol. 64 p. 1417 - 1420

SILVIA SOOKOIAN; CARLOS J. PIROLA

The Exact Mechanism by Which Hepatic Transmembrane 6 Superfamily Member 2 Modulates Triglyceride Metabolism Is Still Uncertain.

GASTROENTEROLOGY; Lugar: Philadelphia; Año: 2016 vol. 151 p. 1033 - 1034

SILVIA SOOKOIAN; GUSTAVO O CASTAÑO; CARLOS JOSE PIROLA

PNPLA3 I148M variant is associated with metabolic stress-response phenotype in patients with nonalcoholic fatty liver disease

HEPATOLOGY (BALTIMORE, MD.); Lugar: New York; Año: 2015 vol. 61 p. 1769 - 1769

SILVIA SOOKOIAN; GUSTAVO O. CASTAÑO; ROMINA SCIAN; PABLO MALLARDI; TOMAS FERNANDEZ GIANOTTI; ADRIANA L. BURGUEÑO; JULIO SAN MARTINO; CARLOS J. PIROLA

Genetic variation in TM6SF2 and the risk of nonalcoholic fatty liver disease and histological disease severity.

HEPATOLOGY (BALTIMORE, MD.); Lugar: New York; Año: 2015 vol. 61 p. 515 - 525

SILVIA C. SOOKOIAN; CARLOS J. PIROLA

TM6SF2 as a genetic risk factor for fibrosis.

HEPATOLOGY (BALTIMORE, MD.); Lugar: New York; Año: 2015 vol. 62 p. 1321 - 1322

CARLOS J PIROLA; ROMINA SCIAN; TOMAS FERNANDEZ GIANOTTI; HERNAN DOPAZO; CRISTIAN ROHR; JULIO SAN MARTINO; GUSTAVO O. CASTAÑO; SILVIA SOOKOIAN

Epigenetic Modifications in the Biology of Nonalcoholic Fatty Liver Disease: The Role of DNA-Hydroxymethylation and TET Proteins

MEDICINE; Lugar: Philadelphia,; Año: 2015 vol. 94 p. 1480 - 1490

PIROLA, CARLOS J.; TOMAS FERNANDEZ GIANOTTI; GUSTAVO CASTAÑO; PABLO MALLARDI; JULIO SAN MARTINO; GONZALEZ LOPEZ LEDESMA MM; FLICHMAN, D; MIRSHAHI F; SANYAL AJ; SILVIA C. SOOKOIAN

Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis

GUT - AN INTERNATIONAL JOURNAL OF GASTROENTEOROLOGY AND HEPATOLOGY; Lugar: Londres; Año: 2015 vol. 64 p. 810 - 812

TELLECHEA, M.; FERNÁNDEZ GIANOTTI T.; ALVARIÑAS J.; GONZALEZ CD.; SOOKOIAN S.; PIROLA, C.J.

Telomere length in the two extremes of abnormal fetal growth and the programming effect of maternal arterial hypertension

Scientific Reports; Lugar: London; Año: 2015 vol. 5 p. 1 - 7

SILVIA SOOKOIAN; CARLOS J. PIROLA

Liver enzymes, metabolomics and genome-wide association studies: From systems biology to the personalized medicine.

WORLD JOURNAL OF GASTROENTEROLOGY; Lugar: Beijing; Año: 2015 vol. 21 p. 711 - 725

CARLOS JOSE PIROLA; SILVIA SOOKOIAN

The dual and opposite role of the TM6SF2-rs58542926 variant in Protecting against Cardiovascular Disease and Conferring Risk for Non-alcoholic fatty liver: A meta-analysis

HEPATOLOGY (BALTIMORE, MD.); Lugar: New York; Año: 2015 vol. 62 p. 1742 - 1756

NANCY SOLÍS; MARGARITA PIZARRO; PABLO QUINTERO; JUAN PABLO ARAB; ARNOLDO RIQUELME; OSLANDO PADILLA; GONZALO CARRASCO; CARLOS JOSE PIROLA; SILVIA SOOKOIAN; MARCO ARRESE

Effects of bile acid sequestration on hepatic steatosis in obese mice.

ANNALS OF HEPATOLOGY; Lugar: Mexico, DF.; Año: 2014 vol. 13 p. 105 - 112

SILVIA C. SOOKOIAN; GUSTAVO O. CASTAÑO; CARLOS J. PIROLA

Modest alcohol consumption decreases the risk of non-alcoholic fatty liver disease: a meta-analysis of 43 175 individuals

GUT - AN INTERNATIONAL JOURNAL OF GASTROENTEOROLOGY AND HEPATOLOGY; Lugar: Londres; Año: 2014 vol. 63 p. 530 - 532

CABRERIZO, R; CASTAÑO G.,; FERNANDEZ GIANOTTI T; GONZALEZ LOPEZ LEDESMA MM; FLICHMAN, D; CARLOS J. PIROLA; SILVIA SOOKOIAN

Promoter DNA Methylation of Farnesoid X Receptor and Pregnane X Receptor Modulates the Intrahepatic Cholestasis of Pregnancy Phenotype

PLOS ONE; Lugar: San Francisco; Año: 2014 vol. 9 p. 87697 - 87714

SILVIA SOOKOIAN; CARLOS J. PIROLA

NAFLD: Metabolic make-up of NASH: from fat and sugar to amino acids.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY; Lugar: Londres; Año: 2014 vol. 11 p. 205 - 207

SILVIA SOOKOIAN; CARLOS JOSE PIROLA

PNPLA3, the history of an orphan gene of the potate tuber protein family that found an organ: the Liver

HEPATOLOGY (BALTIMORE, MD.); Lugar: New York; Año: 2014 vol. 59 p. 2068 - 2071

SILVIA SOOKOIAN; CARLOS J. PIROLA

Genetic and Epigenetic Associations with NAFLD: Focus on Clinical Decision Making and Novel Concepts in Disease Pathogenesis

Curr Hepatol Rep; Año: 2014 vol. 13 p. 97 - 105

SILVIA SOOKOIAN; CARLOS JOSE PIROLA

Personalizing care for nonalcoholic fatty liver disease patients: what are the research priorities?.

PERSONALIZED MEDICINE; Lugar: Londres; Año: 2014 vol. 11 p. 735 - 743

MIN, HK; SOOKOIAN S,; PIROLA CJ; CHENG J; MIRSHAHI F; SANYAL AJ

Metabolic Profiling reveals that pnpla3 induces widespread effects on metabolism beyond Triacylglycerol remodeling in huh-7 hepatoma cells

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY; Lugar: Bethesda; Año: 2014 vol. 307 p. 66 - 76

SCHUMAN ML; PERES DIAZ LS; LANDA MS; TOBLI JE; CAO G; ALVAREZ AL; FINKIELMAN S; PIROLA CJ,; GARCIA, S.L.

Thyrotropin-Releasing Hormone Overexpression induces structural changes of the Left Ventricle in the normal Rat heart

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY; Lugar: Bethesda; Año: 2014 vol. 307 p. 1667 - 1674

BURGUENO, A.L.; FERNANDEZ GIANOTTI T; GONZALES MANSILLA N; PIROLA CJ.; SOOKOIAN S.

Cardiovascular disease is associated with high fat diet-induced liver damage and upregulation of hepatic expression of hypoxia-inducible factor 1 alpha in a rat model .

CLINICAL SCIENCE (LONDON, ENGLAND : 1979); Lugar: Londres; Año: 2013 vol. 124 p. 53 - 63

BURGUENO, ADRIANA L; CABRERIZO, R; GONZALES MANSILLA N; SOOKOIAN, S.; PIROLA, CJ,

Maternal high-fat intake during pregnancy programs metabolic-syndrome-related phenotypes through liver mitochondrial DNA copy number and transcriptional activity of liver PPARGC1A.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY; Lugar: Amsterdam; Año: 2013 vol. 24 p. 6 - 14

SOOKOIAN, S.; PIROLA, C.J.

Systems Biology Elucidates Common Pathogenic Mechanisms between Nonalcoholic and Alcoholic-Fatty Liver Disease

PLOS ONE; Lugar: San Francisco; Año: 2013 vol. 8 p. 58895 - 58906

SILVIA SOOKOIAN; CARLOS J. PIROLA

Epigenetics of Insulin Resistance: An Emerging Field in Translational Medicine

CURRENT DIABETES REPORTS; Lugar: Philadelphia ; Año: 2013 vol. 13 p. 229 - 237

SILVIA C. SOOKOIAN; TOMAS FERNANDEZ GIANOTTI; ADRIANA L. BURGUEÑO; CARLOS J. PIROLA

Fetal metabolic programming and epigenetic modifications: a systems biology approach.

PEDIATRIC RESEARCH; Lugar: The Woodlands, Texas; Año: 2013 vol. 73 p. 531 - 542

SILVIA SOOKOIAN; TOMAS FERNANDEZ GIANOTTI; GUSTAVO O CASTAÑO; CARLOS JOSE PIROLA

. Circulating microRNA-122 signature in nonalcoholic steatohepatitis and cardiovascular disease: a new endocrine system in metabolic syndrome

HEPATOLOGY (BALTIMORE, MD.); Lugar: New York; Año: 2013 vol. 57 p. 2545 - 2547

CARLOS J. PIROLA; T FERNÁNDEZ GIANOTTI; AL BURGUEÑO; MANUEL REY-FUNES; CESAR FABIAN LOIDL; PABLO MALLARDI; JULIO SAN MARTINO; GUSTAVO O CASTAÑO ; SILVIA C. SOOKOIAN

Epigenetic Modification Of Liver Mitochondrial Dna Is Associated With Histological Severity Of Nonalcoholic Fatty Liver Disease

GUT - AN INTERNATIONAL JOURNAL OF GASTROENTEOROLOGY AND HEPATOLOGY; Lugar: Londres 62(9):1356-63-2013; Año: 2013 vol. 62 p. 1356 - 1363

TOMAS FERNANDEZ GIANOTTI; ADRIANA L. BURGUEñO; NOELIA GONZALES MANSILLA; CARLOS JOSE PIROLA; SILVIA SOOKOIAN

Fatty Liver Is Associated with Transcriptional Downregulation of Stearoyl-CoA Desaturase and Impaired Protein Dimerization.

PLOS ONE; Lugar: San Francisco; Año: 2013 vol. 8 p. 76912 - 76923

SILVIA C. SOOKOIAN; CARLOS JOSE PIROLA

Obstructive Sleep Apnea Is Associated with Fatty Liver and Abnormal Liver Enzymes: a Meta-analysis.

OBESITY SURGERY : THE OFFICIAL JOURNAL OF THE AMERICAN SOCIETY FOR BARIATRIC SURGERY AND OF THE OBESITY SURGERY SOCIETY OF AUSTRALIA AND NEW ZEALAND.; Lugar: Berlin; Año: 2013 vol. 23 p. 1815 - 1825

SILVIA C. SOOKOIAN; GUSTAVO O CASTAÑO; CARLOS JOSE PIROLA

Modest alcohol consumption decreases the risk of non-alcoholic fatty liver disease: a meta-analysis of 43 175 individuals.

GUT - AN INTERNATIONAL JOURNAL OF GASTROENTEOROLOGY AND HEPATOLOGY; Lugar: Londres; Año: 2013

SILVIA C. SOOKOIAN; CARLOS J. PIROLA

PNPLA3, the history of an orphan gene of the potate tuber protein family that found an organ: the Liver.

HEPATOLOGY (BALTIMORE, MD.); Lugar: New York; Año: 2013

SILVIA SOOKOIAN; CARLOS JOSE PIROLA

Genetic determinants of acquired cholestasis: A systems biology approach

FRONTIERS IN BIOSCIENCE-LANDMARK; Lugar: NY; Año: 2012 vol. 17 p. 206 - 220

SILVIA SOOKOIAN; CARLOS J. PIROLA

Dna methylation and hepatic insulin resistance and steatosis.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE; Lugar: Philadelphia; Año: 2012 vol. 15 p. 350 - 356

SILVIA C. SOOKOIAN; CARLOS JOSE PIROLA

Genetic Epidemiology of Nonalcoholic Fatty Liver Disease: Toward a Personalized Medicin

CLINICS IN LIVER DISEASE; Lugar: Philadelphia; Año: 2012 vol. 16 p. 467 - 485

SILVIA SOOKOIAN; CARLOS JOSE PIROLA

Alanine and aspartate aminotransferase and glutamine-cycling.

WORLD JOURNAL OF GASTROENTEROLOGY; Lugar: Beijing; Año: 2012 vol. 18 p. 3775 - 3781

SILVIA SOOKOIAN; CARLOS J. PIROLA

Cardiovascular phenotype of nonalcoholic fatty liver disease: Changing the paradigm about the role of distant toxic fat accumulation on vascular disease

HEPATOLOGY (BALTIMORE, MD.); Lugar: Hoboken; Año: 2012 vol. 56 p. 1185 - 1186

SOOKOIAN, S.; PIROLA, C.J.

PNPLA3, the triacylglycerol synthesis/hydrolysis/storage dilemma, and nonalcoholic fatty liver disease.

WORLD JOURNAL OF GASTROENTEROLOGY; Lugar: Beijing; Año: 2012 vol. 18 p. 6018 - 6026

SILVIA SOOKOIAN; CARLOS J. PIROLA

Metabolic Syndrome: From the Genetics to the Pathophysiology

CURRENT HYPERTENSION REPORTS; Año: 2011 vol. 13 p. 149 - 157

SILVIA SOOKOIAN; ADRIANA BURGUEÑO; TOMASFERNÁNDEZ GIANOTTIB; GUILLERMO MARILLET; CARLOS JOSE PIROLA

Odor perception between heterosexual partners: Its association with depression,

BIOLOGICAL PSYCHOLOGY; Año: 2011 vol. 86 p. 153 - 157

J. CARABELLI.; AL BURGUEÑO.; MS ROSSELLI.; FERNANDEZ GIANOTTI, T; LAGO, NR; PIROLA CJ; SOOKOIAN S

High-fat Diet -induced liver steatosis promotes an increase in liver mitochondrial biogenesis in response to hypoxia.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (PRINT); Año: 2011 vol. 15 p. 1329 - 1338

SCHUMAN ML; LANDA MS; TOBLI JE; PERES DIAZ LS; ALVAREZ AL; FINKIELMAN S; PAZ L; CAO G; PIROLA CJ; GARCIA SI

Cardiac thyrotropin-releasing hormone mediates left ventricular hypertrophy in spontaneously hypertensive rats.

HYPERTENSION; Año: 2011 vol. 57 p. 103 - 109

SOOKOIAN S; PIROLA CJ

Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on susceptibility and histological severity of nonalcoholic fatty liver disease.

HEPATOLOGY (BALTIMORE, MD.); Año: 2011 vol. 53 p. 1883 - 1894

ROSSELLI MS; BURGUEÑO A; PIROLA CJ; SOOKOIAN S

Cyclooxygenase inhibition upregulates liver carnitine palmitoyltransferase 1A (CPT1A) expression and improves fatty liver.

HEPATOLOGY (BALTIMORE, MD.); Año: 2011 vol. 53 p. 2143 - 2144

SILVIA SOOKOIAN; TOMAS FERNÁNDEZ GIANOTTI; MARIA SOLEDAD ROSSELLI; ADRIANA L. BURGUEÑO; GUSTAVO O. CASTAÑO; CARLOS J. PIROLA

Liver transcriptional profile of atherosclerosis-related genes in human

ATHEROSCLEROSIS; Lugar: Amsterdam; Año: 2011 vol. 218 p. 378 - 385

S.SOOKOIAN; T FERNÁNDEZ GIANOTTI; AL BURGUEÑO; CJ PIROLA

Insulin resistance and epigenetic regulation: insights from human studies and prospects for future research.

BioMolecular Concepts; Lugar: BERLIN; Año: 2011 vol. 2 p. 445 - 457

SOOKOIAN S; PIROLA CJ

Targeting the renin-angiotensin system: Potential beneficial effects of the angiotensin II receptor bloxkers in patients with nonalcholic steatohepatitis.

HEPATOLOGY (BALTIMORE, MD.); Lugar: NJ USA.; Año: 2011 vol. 54 p. 2277 - 2278

SOOKOIAN S; PIROLA CJ

Methodological Concerns About a Recent Meta-Analysis of the Influence of the I148M Variant ofPatatin-Like Phospholipase Domain Containing 3 on the Susceptibility and Histological Severity of Nonalcoholic Fatty Liver Disease

HEPATOLOGY (BALTIMORE, MD.); Lugar: NJ, USA; Año: 2011 vol. 53 p. 2146 - 2147

TOMAS FERNÁNDEZ GIANOTTI; GUSTAVO CASTAÑO; CAROLINA GEMMA; ADRIANA L. BURGUEÑO; MARIA SOLEDAD ROSSELLI; CARLOS J PIROLA; SILVIA SOOKOIAN

Mitochondrial DNA copy number is modulated by geneticvariation in the signal transducer and activator of transcription 3 (STAT3)

METABOLISM-CLINICAL AND EXPERIMENTAL; Lugar: Amsterdam; Año: 2011 vol. 60 p. 1142 - 1149

SOOKOIAN S; FERNANDEZ GIANOTTI T; GEMMA C; BURGUEÑO A; PIROLA CJ,

Role of genetic variation in insulin-like growth factor 1 receptor on insulin resistance and arterial hypertension.

JOURNAL OF HYPERTENSION; Lugar: England; Año: 2010 vol. 28 p. 1194 - 1202

BURGUEÑO A.; GEMMA C.; GIANOTTI TF.; SOOKOIAN S.; PIROLA CJ.

Increased levels of resistin in rotating shift workers: A potential mediator of

ATHEROSCLEROSIS; Año: 2010 vol. 210 p. 625 - 629

GEMMA C; SOOKOIAN S; DIEUZEIDE G; GARCIA SI; GIANOTTI, T. F.; GONZALEZ CD; PIROLA CJ,

Methylation of TFAM gene promoter in peripheral white blood cells is associated with insulin resistance in adolescents.

MOLECULAR GENETICS AND METABOLISM; Año: 2010 vol. 100 p. 83 - 87

CASTAÑO G.,; BURGUEÑO A.; FERNÁNDEZ GIANOTTI T.; PIROLA CJ.; SOOKOIAN S.

The influence of common gene variants of the xenobiotic receptor ( PXR) in genetic susceptibility to intrahepatic cholestasis of pregnancy

ALIMENTARY PHARMACOLOGY & THERAPEUTICS.; Año: 2010 vol. 31 p. 583 - 592

SOOKOIAN S; CASTANO G; BURGUEÑO A; GIANOTTI, T. F.; ROSSELLI MS; PIROLA CJ,

The nuclear receptor PXR gene variants are associated with liver injury in nonalcoholic fatty liver disease.

PHARMACOGENETICS AND GENOMICS; Lugar: United States; Año: 2010 vol. 20 p. 1 - 8

SOOKOIAN S; CASTANO G; BURGUEÑO A; ROSSELLI MS; GIANOTTI, T. F.; MALLARDI P; SAN MARTINO J; PIROLA CJ,

Circulating levels and hepatic expression of molecular mediators of atherosclerosis in nonalcoholic fatty liver disease.

ATHEROSCLEROSIS; Lugar: Amsterdam; Año: 2010 vol. 209 p. 585 - 591

SILVIA SOOKOIAN; TOMAS FERNANDEZ GIANOTTI; ADRIANA BURGUEÑO; CARLOS JOSE PIROLA

Gene-gene interaction between serotonin transporter

CHRONOBIOLOGY INTERNATIONAL; Año: 2010 vol. 6 p. 1202 - 1218

SILVIA SOOKOIAN; MARIA SOLEDAD ROSSELLI; CAROLINA GEMMA; ADRIANA L. BURGUEÑO; TOMAS FERNÁNDEZ GIANOTTI; GUSTAVO O. CASTAÑO; CARLOS J. PIROLA

Epigenetic Regulation of Insulin Resistance in Nonalcoholic Fatty Liver Disease: Impact of LiverMethylation of the Peroxisome Proliferator–Activated Receptor ã Coactivator 1 á Promoter

HEPATOLOGY (BALTIMORE, MD.); Año: 2010 vol. 52 p. 1992 - 2000

ADRIANA L. BURGUEÑO; JULIETA CARABELLI; SILVIA SOOKOIAN; CARLOS J. PIROLA

The Impact of Maternal High-Fat Feeding on Liver and Abdominal Fat Accumulation in Adult Offspring Under a Long-Term High-Fat Diet

HEPATOLOGY (BALTIMORE, MD.); Año: 2010 vol. 51 p. 2234 - 2235

SILVIA SOOKOIAN; CAROLINA GEMMA; CARLOS J. PIROLA

Influence of hepatocyte nuclear factor 4a (HNF4a) gene variants on the risk of type 2 diabetes: A meta-analysis in 49,577 individuals

MOLECULAR GENETICS AND METABOLISM; Año: 2010 vol. 99 p. 80 - 89

MARÍA S.LANDA; SILVIA I. GARCÍA; CARLOS J. PIROLA

Diencephalic Thyrotropin-Releasing Hormone(trh) May Participate un letpin-Mediated Control Of arterial Blood Pressure(Abp) Exerted By Protein Tyrosine Phosphatase 1b

CIRCULATION; Año: 2010 vol. 21 p. 419 - 420

STEPHAN BUCH; CLEMENS SCHAFMAYER; HENRY VÖLZKE; MARCUS SEEGER; JUAN F. MIQUEL,; SILVIA C. SOOKOIAN; JAN H. EGBERTS; ALEXANDER ARLT; CARLOS J. PIROLA; MARKUS M. LERCH; ULRICH JOHN; ANDRE FRANKE; OLIVER VON KAMPEN,*; MARIO BROSCH; MICHAEL NOTHNAGEL; WOLFGANG KRATZER; BERNHARD O. BOEHM; DIETER C. BRÖRING; STEFAN SCHREIBER; MICHAEL KRAWCZAK; JOCHEN HAMPE

Loci From a Genome-Wide Analysis of Bilirubin Levels Are Associated With Gallstone Risk and Composition

GASTROENTEROLOGY; Año: 2010 vol. 139 p. 1942 - 1951

BURGUEÑO A; CARABELLI J; SOOKOIAN S; PIROLA CJ,

The impact of maternal high-fat feeding on liver and abdominal fat accumulation in adult offspring under a long-term high-fat diet.

HEPATOLOGY (BALTIMORE, MD.); Lugar: United States ; Año: 2010 p. 1 - 2

SOOKOIAN S; CASTANO G; GIANOTTI T, F.; GEMMA C; PIROLA CJ,

Polymorphisms of MRP2 (ABCC2) are associated with susceptibility to nonalcoholic fatty liver disease.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY; Lugar: United States ; Año: 2009 p. 765 - 770

LOPEZ VERRILLI MA,; PIROLA CJ,; PASCUAL MM; DOMINICI FP; TURYN D; GIRONACCI MM.

Angiotensin-(1-7) through AT receptors mediates tyrosine hydroxylase degradation via the ubiquitin-proteasome pathway.

JOURNAL OF NEUROCHEMISTRY; Lugar: England; Año: 2009 p. 326 - 335

SOOKOIAN S; GIANOTTI, T. F.; SCHUMAN M; PIROLA CJ,

Gene prioritization based on biological plausibility over genome wide association studies renders new loci associated with type 2 diabetes.

GENETICS IN MEDICINE; Lugar: United States ; Año: 2009 p. 338 - 343

SOOKOIAN S; PIROLA CJ,

Shift work and subclinical atherosclerosis: recommendations for fatty liver disease detection.

ATHEROSCLEROSIS; Año: 2009 vol. 207 p. 346 - 347

SOOKOIAN, S.; CASTANO G; BURGUEÑO A; FERNANDEZ GIANOTTI T; ROSSELLI MS; PIROLA CJ,

A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity.

JLR PAPERS IN PRESS; Lugar: United States ; Año: 2009 p. 2111 - 2116

GEMMA C,; SOOKOIAN S; ALVARIÑAS J; GARCIA SI; QUINTANA L; KANEVSKY D; GONZALEZ CD; PIROLA CJ,

Maternal pregestational BMI is associated with methylation of the PPARGC1A promoter in newborns.

OBESITY; Año: 2009 vol. 17 p. 1032 - 1039

BURGUEÑO A,; SOOKOIAN S; FERNANDEZ GIANOTTI T; GEMMA C; PIROLA CJ

Genetic Variation in the FAAH Gene and Metabolic syndrome?related Phenotypes

OBESITY; Año: 2009 vol. 17 p. 1979 - 1980

SOOKOIAN S; CASTANO G; BURGUEÑO A; GIANOTTI T, F.; ROSSELLI MS; PIROLA CJ

A diagnostic model to differentiate simple steatosis from nonalcoholic

CLINICAL BIOCHEMISTRY; Año: 2009 vol. 42 p. 624 - 629

ROSSELLI MS; BURGUEÑO A; CARABELLI J; SCHUMAN M; PIROLA CJ,; SOOKOIAN S

Losartan reduces liver expression of plasminogen activator inhibitor-1 (PAI-1) in

ATHEROSCLEROSIS; Año: 2009 vol. 206 p. 119 - 126

SOOKOIAN S; FERNANDEZ GIANOTTI T; PIROLA CJ

Role Of The C-344t Aldosterone Synthase Gene Variant In Left Ventricular Mass And Left Ventricular Structure-Related Phenotypes.

HEART (BRITISH CARDIAC SOCIETY); Lugar: London, UK; Año: 2008 vol. 94 p. 903 - 910

SOOKOIAN S; GEMMA C; FERNANDEZ GIANOTTI T; BURGUEÑO A; CASTAÑO, G.; PIROLA CJ

Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity.

AMERICAN JOURNAL OF CLINICAL NUTRITION; Lugar: Houston, TX, USA.; Año: 2008 vol. 87 p. 1606 - 1615

SOOKOIAN S; CASTAÑO, G.; FERNANDEZ GIANOTTI T; GEMMA C; ROSSELLI MS; PIROLA CJ

Genetic variants in STAT3 are associated with nonalcoholic fatty liver disease.

CYTOKINE.; Lugar: Ámsterdam, Holland.; Año: 2008 vol. 44 p. 201 - 206

SOOKOIAN S; PIROLA CJ

Non-alcoholic fatty liver disease is strongly associated with carotid atherosclerosis: A systematic review.

JOURNAL OF HEPATOLOGY; Lugar: Amsterdam, Holland.; Año: 2008 vol. 49 p. 600 - 607

LANDA MS; GARCIA SI; SCHUMAN ML; ALVAREZ AL; FINKIELMAN S; PIROLA CJ

Thyrotropin-Releasing Hormone Precursor Gene Knocking Down Impedes Melanocortin-Induced Hypertension in Rats.

HYPERTENSION; Lugar: Hagerstown,MD, USA ; Año: 2008 vol. 52 p. 8 - 8

FERNANDEZ GIANOTTI T; SOOKOIAN S; DIEUZEIDE G; GARCIA SI; GEMMA C; GONZALEZ CD; PIROLA CJ

A Decreased Mitochondrial DNA Content Is Related to Insulin Resistance in Adolescents.

Obesity (Silver Spring, ex Obesity Research); Lugar: London, United Kindom.; Año: 2008 vol. 16 p. 1591 - 1595

SOOKOIAN S; BURGUEÑO A; CASTAÑO, G.; PIROLA CJ

Should nonalcoholic fatty liver disease be included in the definition of metabolic syndrome? A cross-sectional comparison with adult treatment panel III criteria in nonobese nondiabetic subjects: response to Musso et al.

DIABETES CARE; Lugar: Alexandria, VA, USA.; Año: 2008 vol. 31 p. 42 - 43

SOOKOIAN S; CASTANO G; BURGUEÑO A; FERNANDEZ GIANOTTI T; PIROLA CJ

Association Of The Multidrug-Resistance-Associated Protein Gene (Abcc2) Variants With Intrahepatic Cholestasis Of Pregnancy.

JOURNAL OF HEPATOLOGY; Lugar: Amsterdam.; Año: 2008 vol. 48 p. 125 - 132

SOOKOIAN S; CASTAÑO, G.; PIROLA CJ

Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy.

World Journal of Gastroenterology; Lugar: Beijing, China.; Año: 2008 vol. 14 p. 2126 - 2127

FERNANDEZ GIANOTTI T; SOOKOIAN S; DIEUZEIDE G; GARCIA SI; GEMMA C; GONZALEZ CD; PIROLA CJ

Study of Genetic Variation in the STAT3 on Obesity and Insulin Resistance in Male Adults.

Obesity (Silver Spring, ex Obesity Research); Lugar: London, United Kindom; Año: 2008 vol. 16 p. 1702 - 1707

SOOKOIAN S; FERNANDEZ GIANOTTI T; GEMMA C; BURGUEÑO A; PIROLA CJ,

Contribution Of The Functional 5-Httlpr Variant Of The Slc6a4 Gene To Obesity Risk In Male Adults.

Obesity (Silver Spring); Lugar: London, United Kindom; Año: 2008 vol. 16 p. 488 - 491

SOOKOIAN S; GEMMA C; FERNANDEZ GIANOTTI T; BURGUEÑO A; ALVAREZ A; GONZALEZ C; PIROLA, CJ

Effects of rotating shift work on biomarkers of metabolic syndrome and inflammation.

JOURNAL OF INTERNAL MEDICINE; Lugar: London, UK; Año: 2007 vol. 261 p. 285 - 292

SOOKOIAN S; GEMMA C; FERNANDEZ GIANOTTI T; BURGUEÑO A; ALVAREZ A; GONZALEZ C; PIROLA CJ

Serotonin and Serotonin Transporter Gene Variant in Rotating Shift Workers.

SLEEP.; Lugar: Winchester, IL; Año: 2007 vol. 30 p. 1049 - 1053

SOOKOIAN S; PIROLA CJ

Genetics of the cardiometabolic syndrome: new insights and therapeutic implications

Therapeutic Advances in Cardiovascular Disease; Lugar: Los Angeles, London, New Delhi and Singapore; Año: 2007 vol. 1 p. 37 - 47

BURGUEÑO A; LANDA MS; SCHUMAN ML,; ALVAREZ A; CARABELLI J; GARCIA SI; PIROLA CJ

Association Between Diencephalic Thyroliberin And Arterial Blood Pressure In Agouti-Yellow And Ob/Ob Mice May Be Mediated By Leptin.

METABOLISM-CLINICAL AND EXPERIMENTAL; Lugar: Amsterdam; Año: 2007 vol. 56 p. 1439 - 1443

SOOKOIAN S; CASTAÑO, G.; GEMMA C; FERNANDEZ GIANOTTI T; PIROLA CJ

Common Genetic Variations In Clock Transcription Factor Are Associated With Nonalcoholic Fatty Liver Disease.

World Journal of Gastroenterology; Lugar: Beijing, China.; Año: 2007 vol. 13 p. 4242 - 4248

LANDA MS; SCHUMAN ML,; BURGUEÑO A; ALVAREZ A; GARCIA SI; PIROLA CJ

Sirna-Mediated Silencing Of The Diencephalic Thyrotropin-Releasing Hormone Precursor Gene Decreases The Arterial Blood Pressure In The Obese Agouti Mice.

Frontiers in Biosciences; Lugar: New York; Año: 2007 vol. 12 p. 3431 - 3435

LANDA MS; GARCIA SI; SCHUMAN ML,; BURGUEÑO A; ALVAREZ A; SARAVIA F; GEMMA C; PIROLA CJ

Knocking down the diencephalic thyrotropin-releasing hormone precursor gene normalizes obesity-induced hypertension in the rat

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM; Lugar: Bethesda, MD; Año: 2007 vol. 292 p. 1388 - 1394

SOOKOIAN S; GEMMA C; GARCIA SI; FERNANDEZ GIANOTTI T; DIEUZEIDE G; ROUSSOS A; TONIETTI M; TRIFONE L; KANEVSKY D; GONZALEZ C; PIROLA CJ

Short Allele of Serotonin Transporter Gene Promoter Is a Risk Factor for Obesity in Adolescents.

Obesity; Lugar: Silver Spring; Año: 2007 vol. 15 p. 271 - 276

SOOKOIAN, S.; GIANOTTI, T. F.; GONZALEZ, CLAUDIO; CARLOS JOSE PIROLA

Association of the C-344T aldosterone synthase gene variant with essential hypertension: a meta-analysis

Journal of Hypertension; Lugar: Hagerstown,MD, USA; Año: 2007 vol. 25 p. 5 - 13

C GEMMA; SOOKOIAN, S.; J. ALVARIÑAS; L QUINTANA; GARCIA, SILVIA I; D,, K.; GONZALEZ, CLAUDIO; CARLOS JOSE PIROLA

Mitochondrial DNA depletion in small- and large-for-gestational-age newborns.

Obesity; Lugar: Silver Spring, MD, USA; Año: 2006 vol. 14 p. 2193 - 2199

AJ, KLECHA; AM, GENARO; G, GORELIK; ML, BARRERO. ARCOS.; DM, SILVERMAN.; SCHUMAN, M.; GARCIA, S.; CARLOS JOSE PIROLA; GA., CREMASCHI.

Integrative study of hypothalamus-pituitary-thyroid-immune system interaction: thyroid hormone-mediated modulation of lymphocyte activity through the protein kinase C signaling pathway.

Journal of Endocrinology; Lugar: Bristol, UK; Año: 2006 vol. 189 p. 45 - 55

SOOKOIAN, S.; GARCIA, S.; PORTO, P.; DIEUZEIDE, G.; GONZALEZ, CLAUDIO; CARLOS JOSE PIROLA

Peroxisome Proliferator-Activated Receptor Gamma (Pparg) And Its Coactivator-1 Alpha (Pgc-1a) May Be Associated With Features Of The Metabolic Syndrome In Adolescents.

J Mol Endocrinol; Año: 2005 vol. 35 p. 375 - 382

SOOKOIAN, S.; GARCIA, S.; GIANOTTI, T. F.; DIEUZEIDE, G.; GONZALEZ, CLAUDIO; CARLOS JOSE PIROLA

The G-308a Promoter Variant Of The Tumor Necrosis Factor-a Gene Is Associated With Hypertension In Adolescents Harboring The Metabolic Syndrome

American Journal of Hypertension; Año: 2005 vol. 18 p. 1271 - 1275

HELLER PG,; GLEMBOTSKY AC; GANDHI MJ; CUMMINGS CL; PIROLA CJ; MARTA RF; KORNBLIHTT LI; DRACHMAN JG; MOLINAS FC.

Low Mpl receptor expression in a pedigree with familial platelet disorder with predisposition to acute myelogenous leukemia and a novel AML1 mutation.

BLOOD, THE JOURNAL OF THE AMERICAN SOCIETY OF HEMATOLOGY - PRINT; Año: 2005 vol. 15 p. 4664 - 4670

SOOKOIAN S; GARCIA SI; FERNANDEZ GIANOTTI T; DIEUZEIDE G,; GONZALEZ C; PIROLA CJ

The G-308A promoter variant of the tumor necrosis factor-alpha gene is associated with hypertension in adolescents harboring the metabolic syndrome.

AMERICAN JOURNAL OF HYPERTENSION; Lugar: United States; Año: 2005 vol. 18 p. 1271 - 1275

MARTA RF; GOETTE NP; LEV PR,; CHAZARRETA CD,; PIROLA CJ,; MOLINAS FC.

Normal platelets possess the soluble form of IL-6 receptor.

CYTOKINE.; Año: 2005 vol. 7 p. 13 - 17

SOOKOIAN S; CASTANO G; GARCIA SI; VIUDEZ P; GONZALEZ C; PIROLA CJ

A1166C angiotensin II type 1 receptor gene polymorphism may predict hemodynamic response to losartan in patients with cirrhosis and portal hypertension.

AMERICAN JOURNAL OF GASTROENTEROLOGY; Lugar: United Kingdom; Año: 2005 vol. 100 p. 636 - 642

LEV PR; SALIM JP; KORNBLIHTT LI; PIROLA CJ; MARTA RF; HELLER PG,; MOLINAS FC.

PDGF-A, PDGF-B, TGFbeta, and bFGF mRNA levels in patients with essential thrombocythemia treated with anagrelide.

AMERICAN JOURNAL OF HEMATOLOGY; Lugar: United States; Año: 2005 vol. 78 p. 155 - 157

LANDA MS; GARCÍA SI; LIBERJEN L,; SCHUMAN ML,; FINKIELMAN S,; PIROLA CJ

Parathyroid hormone-related protein overexpression decreases blood pressure in spontaneously hypertensive rats.

CLINICAL AND EXPERIMENTAL HYPERTENSION; Lugar: New York; Año: 2005 vol. 27 p. 343 - 354

GARCIA SI; PIROLA CJ

Thyrotropin-releasing hormone in cardiovascular pathophysiology.

REGULATORY PEPTIDES; Lugar: Netherlands; Año: 2005 vol. 30 p. 239 - 246

SOOKOIAN S; GONZALEZ C; PIROLA CJ

Meta-analysis on the G-308A tumor necrosis factor alpha gene variant and phenotypes associated with the metabolic syndrome.

OBESITY RESEARCH; Lugar: Silver Spring, Md; Año: 2005 vol. 13 p. 2122 - 2131

MARTA R,; GOETTE N,; LEV P; HELLER P,; KORNBLIHTT L; VASSALLU P,; GLEMBOTSKY A,; PIROLA C,; MOLINAS F.

Increased levels of plasma interleukin-6 soluble receptor in patients with essential thrombocythemia.

HAEMATOLOGICA; Lugar: Italy; Año: 2004 vol. 89 p. 657 - 663

SOOKOIAN S; PIROLA CJ

Pharmacogenetics/pharmacogenomics in clinical practice

MEDICINA (BUENOS AIRES); Lugar: Buenos Aires; Año: 2004 vol. 64 p. 563 - 567

PORTO I; GARCIA SI; DIEUZEIDE G,; GONZALEZ C; LANDA MS; PIROLA CJ

Clinical features of the metabolic syndrome in adolescents: minor role of the Trp64Arg beta3-adrenergic receptor gene variant.

PEDIATRIC RESEARCH; Año: 2004 vol. 55 p. 836 - 841

PORTO, P.; GARCIA, S.; DIEUZEIDE, G.; GONZALEZ, CLAUDIO; SPATARO, R.; CARLOS JOSE PIROLA

Renin-Angiotensin-Aldosterone System Loci and Nonallelic Interactions in Young-Onset Essential Hypertension

Clin Exp Hyperten; Año: 2003 vol. 25 p. 117 - 130

A.M, V.; PORTO, P.; GARCIA, SILVIA I; DIEUZEIDE, G.; KIRSZNER,, T.; SPATARO, R.; GONZALEZ, CLAUDIO; CARLOS JOSE PIROLA

Hyperhomocyst(e)inemia as a risk factor for young-onset essential hypertension

Journal of Human Hypertension; Año: 2003 vol. 17 p. 361 - 364

GARCIA, SILVIA I; LANDA, M. S.; PORTO, P.; ÁLVAREZ, AZUCENA L; SCHUMAN, M.; FINKIELMAN, SAMUEL; CARLOS JOSE PIROLA

Thyrotropin-releasing hormone decreases leptin and mediates the leptin-induced pressor effect

Hypertension; Año: 2002 vol. 39 p. 491 - 495

GARCIA, SILVIA I; ÁLVAREZ, AZUCENA L; PORTO, PATRICIA I; VAM, G.; FINKIELMAN, SAMUEL; CARLOS JOSE PIROLA

Antisense inhibition of thyrotropin releasing hormone reduces arterial blood pressor in spontaneously hypertensive rats.

Hypertension; Año: 2001 vol. 37 p. 365 - 370

GARCIA, SILVIA I; PORTO, PATRICIA I; DIEUZEIDE, G.; LANDA, M. S.; KIRSZNER,, T.; PLOTQUIN, Y.; GONZALEZ, CLAUDIO; CARLOS JOSE PIROLA

The thyrotropin-releasing hormone receptor (trhr) gene is associated with essential hypertension

Hypertension; Lugar: Hagerstown,MD; Año: 2001 vol. 38 p. 683 - 687

CARLOS JOSE PIROLA; LEONARDI, FABIANA; DIEUZEIDE, G.; PORTO, PATRICIA I; KIRSZNER, T.; PLOTQUIN, YANKEL; GARCIA, SILVIA I

Thyrotropin-releasing hormone receptor gene variants are associated to essential hypertension.

Hypertension; Lugar: Hagerstown,MD; Año: 2001 vol. 37 p. 1032 - 1032

GARCIA, SILVIA I; PORTO, PATRICIA I; ÁLVAREZ, AZUCENA L; SCHUMAN, M.; FINKIELMAN, SAMUEL; CARLOS JOSE PIROLA

A novel Thyrotropin-releasing Hormone-Leptin Interaction

Hypertension; Año: 2001 vol. 38 p. 508 - 508

PORTO, PATRICIA I; GARCIA, SILVIA I; DIEUZEIDE, G.; GARFUNKEL, VICTORIA AM; LEONARDI, FABIANA; PERUSCO, A.; SPATARO, R.; GONZALEZ, CLAUDIO; CARLOS JOSE PIROLA

Nonallelic interactions may be more important than single genes in essential hypertension.

Hypertension; Año: 2001 vol. 37 p. 1032 - 1032

GARCIA, S.; PORTO, P.; MARTINEZ, V.; ÁLVAREZ, AZUCENA L; FINKIELMAN, SAMUEL; CARLOS JOSE PIROLA

Expression of TRH and TRH-like peptides in a human glioblastoma astrocytoma cell line (U-373-MG).

Journal of Endocrinology; Año: 2000 vol. 166 p. 697 - 703

GARCIA, SILVIA I; ÁLVAREZ, AZUCENA L; PORTO, PATRICIA I; P, H.; GARFUNKEL, VICTORIA AM; FINKIELMAN, SAMUEL; CARLOS JOSE PIROLA

Central antisense treatment against thyroliberin normalizes blood pressure in spontaneously hypertensive rats without affecting thyroid status

Hypertension; Año: 2000 vol. 36 p. 729 - 730

MARTA, ROSANA F; GOETTE, NORA P; LEV, PAOLA R; CARLOS JOSE PIROLA; MOLINAS, FELISA C

IL-6 soluble and anchored receptor in mononuclear cells from patients with essential thrombocythemia

Blood; Año: 1999 vol. 94 p. 1 - 1

CARLOS JOSE PIROLA; PORTO, PATRICIA I; SIMSOLO, R.; GARCIA, SILVIA I; GRUNFELD, B.; ÁLVAREZ, AZUCENA L

Association of renin-angiotensin system genes with ambulatory blood pressure in adolescents

Hypertension; Año: 1999 vol. 33 p. 1088 - 1088

CARLOS JOSE PIROLA

" Factores genéticos en Hipertensión Arterial Esencial"

Boletín de la Sociedad Argentina de Hipertensión Arterial; Año: 1999 vol. 1 p. 5 - 6

GARCIA, SILVIA I; CLEMENS, T.; FAGIN, J.; FINKIELMAN, SAMUEL; CARLOS JOSE PIROLA

Parathyroid hormone-related protein expression in vascular smooth muscle of spontaneously hypertensive rats: evidence for lack of response to angiotensin II

Journal of Hypertension; Año: 1998 vol. 16 p. 1467 - 1474

CARLOS JOSE PIROLA; PORTO, PATRICIA I; KIRSZNER, T.; ÁLVAREZ, AZUCENA L; PLOTQUIN, YANKEL; SHAURLI, D.; LAJFER, J.; GONZALEZ, CLAUDIO; GARCIA, SILVIA I

Thyrotropin-Releasing Hormone Receptor Gene Variants are Associated to Essential Arterial Hypertension (HT).

JACC; Año: 1998 vol. 31 p. 1 - 1

GARCIA, SILVIA I; CARLOS JOSE PIROLA

"Hormona liberadora de tirotrofina (TRH) e hipertensión experimental."

Iberoamerican Journal of Hypertension; Año: 1997 vol. 1 p. 63 - 71

GARCIA, S.; PORTO, P.; ÁLVAREZ, AZUCENA L; FINKIELMAN, SAMUEL; CARLOS JOSE PIROLA

Central Overexpression of the TRH Precursor Gene Induces Hypertension in Rats: antisense reversal

Hypertension; Año: 1997 vol. 30 p. 759 - 766

CARLOS JOSE PIROLA; GARCIA, S.; CLEMENS, T.; FAGIN, J.

. Evidence for alterations of expression of parathyroid hormone related protein (PTHrP) in spontaneously hypertensive rats (SHR

Hypertension; Año: 1997 vol. 29 p. 887 - 887

GARCIA, S.; PORTO, P.; ÁLVAREZ, AZUCENA L; FINKIELMAN, SAMUEL; CARLOS JOSE PIROLA

Thyrotropin-releasing Hormone precursor (preTRH) gene over-expression induces hypertension in rats: antisense reversal.

Hypertension; Año: 1997 vol. 29 p. 886 - 886

DELORENZI, A.; PEDREIRA, ,. M.; ROMANO, A.; GARCIA, S.; CARLOS JOSE PIROLA; NAHMOD, V.; MALDONADO, H.

Angiotensin II Enhances Long-Term Memory in the Crab Chasmagnatus

Brain Research Bulletin; Año: 1996 vol. 41 p. 211 - 220

GARCIA, S.; DABSYS, S.; MARTINEZ, V.; DELORENZI, A.; SANTAJULIANA, D.; NAHMOD, V.; FINKIELMAN, SAMUEL; CARLOS JOSE PIROLA

Thyrotropin-releasing Hormone (TRH) Hyperactivity in the Preoptic Area (POA) of the Spontaneoulsy Hypertensive Rats (SHR).

Hypertension; Año: 1995 vol. 26 p. 1105 - 1110

DELORENZI, A.; PEDREIRA, ,. M.; ROMANO, A.; CARLOS JOSE PIROLA; NAHMOD, V.; MALDONADO, H.

Acute administration of angiotensin II improves long-term habituation in the crab chasmagnathus

Neuroscience Letters; Año: 1995 vol. 196 p. 193 - 196

OKANO, K.; CARLOS JOSE PIROLA; WANG, H.; FORRESTER, J.; FAGIN, J.; CLEMENS, T.

Involvement of cell cycle and mitogen-activated pathways in induction of parathyroid hormone related protein gene expression in rat aortic smooth muscle cells.

Endocrinology; Año: 1995 vol. 136 p. 1782 - 1789

CARLOS JOSE PIROLA

"La proteina relacionada con la parathormona (PTHrP): una novel proteina en busca de una función

Medicina-Buenos Aires; Año: 1995 vol. 55 p. 470 - 472

OKANO, K.; WU, S.; HUANG, X.; CARLOS JOSE PIROLA; JUPPNER, H.; ABOU-SAMRA, A.; SEGRE, G. V.; IWASAKI, K.; FAGIN, J.; CLEMENS, T.

Parathyroid Hormone (PTH)/PTH-Related Protein (PTHrP) Receptor and Its Messenger Ribonucleic Acid in Rat Aortic Vascular Smooth Muscle Cells and UMR Osteoblastic-Like Cells: Cell-Specific Regulation by Angiotensin II and PTHrP

Endocrinology; Año: 1994 vol. 135 p. 1093 - 1099

CARLOS JOSE PIROLA; WANG, H.; STRGACICH, M.; CERCEK, B.; FORRESTER, J.; CLEMENS, T.; FAGIN, J.

Mechanical Stimuli Induce Vascular Parathyroid Hormone-Related Protein Gene Expression In Vivo and In Vitro.

Endocrinology; Año: 1994 vol. 134 p. 2230 - 2236

KAMYAR, A.; CARLOS JOSE PIROLA; WANG, H.; SHARIFI, B.; MOHAN, S.; FORRESTER, J.; FAGIN, J.

Expression and IGF-dependent proteolysis of IGFBP-4 are regulated by cell confluency in vascular smooth muscle cells

Circulation Research; Año: 1994 vol. 74 p. 576 - 585

CARLOS JOSE PIROLA; KAMYAR, A.; WANG, H.; WU, S.; FORRESTER, J.; CLEMENS, T.; FAGIN, J.

Angiotensin II Regulates Parathyroid Hormone-related Protein Expression in Cultured Rat Aortic Smooth Muscle Cells through Transcriptional and Post-transcriptional Mechanisms

Journal of Biological Chemistry; Lugar: ; Año: 1993 vol. 268 p. 1987 - 1994

WU, S.; CARLOS JOSE PIROLA; GREEN, J.; YAMAGUCHI, D.; OKANO, K.; JUPPNER, H.; FORRESTER, J.; FAGIN, J.; CLEMENS, T.

Effects of N-terminal, mid-region and C-terminal parathyroid hormone related peptides on adenosine 3', 5' monophosphate and cytoplasmic free calcium in rat smooth muscle cells and UMR-106 osteoblast-like cells.

Endocrinology; Año: 1993 vol. 133 p. 2437 - 2444

CARLOS JOSE PIROLA; WANG, H.; STRGACICH, M.; CERCEK, B.; FORRESTER, J.; CLEMENS, T.; FAGIN, J.

Mechanical Stimuli Induce vascular Parathyroid Hormone-Related Protein Gene Expression In Vivo and In Vitro

Clinical Res; Año: 1993 vol. 41 p. 1 - 1

CARLOS JOSE PIROLA; GARCIA, SILVIA I

Pasado y Presente de la cromatografía líquida de alta Presión: alguna de sus aplicaciones.

Revista de la Asociación Bioquímica Argentina; Año: 1993 p. 1 - 1

GARCIA, S.; DABSYS, S.; SANTAJULIANA, D.; DELORENZI, A.; FINKIELMAN, SAMUEL; NAHMOD, V.; CARLOS JOSE PIROLA

Interaction between thyrotropin-releasing hormone and muscarinic cholinergic system in the rat brain

Journal of Endocrinology; Año: 1992 vol. 134 p. 215 - 219

GARCIA, S.; CARLOS JOSE PIROLA; DABSYS, S.; SANTAJULIANA, D.; DELORENZI, A.; FINKIELMAN, SAMUEL; NAHMOD, V.

Thecholinergic system participates in thyrotropin-releasing hormone (TRH) regulation.

Neuroscience Letters; Año: 1992 vol. 135 p. 193 - 195

GIANNELLA- NETO, D.; KAMYAR, A.; SHARIFI, B.; CARLOS JOSE PIROLA; KUPFER, J.; ROSENFELD, R.; FORRESTER, J.; FAGIN, J.

Platelet- derived growth factor isoforms decrease insulin-like growth factor I gene expression in rat vascular smooth muscle cells and selectively stimulate the biosynthesis of insulin-like growth factor binding protein 4.

Circulation Res; Año: 1992 vol. 71 p. 646 - 656

ÁLVAREZ, AZUCENA L; DELORENZI, A.; SANTAJULIANA, D.; FINKIELMAN, SAMUEL; NAHMOD, V.; CARLOS JOSE PIROLA

Central bradykininergic system in normotensive and hypertensive rats.

Clinical science (London, England : 1979); Año: 1992 vol. 82 p. 513 - 519

FANELI, M.; NAHMOD, V.; TORRES, N.; SANTAJULIANA, D.; GARCIA, S.; FINKIELMAN, SAMUEL; CARLOS JOSE PIROLA

Brain amines in glucocorticoid-induced hypertension in the rat.

Neuroscience Letters; Año: 1992 vol. 135 p. 189 - 192

SHARIFI, B.; LAFLEUR, D.; CARLOS JOSE PIROLA; FAGIN, J.; FORRESTER, J.

Angiotensin II regulates tenascin gene expression in vascular smooth muscle cells.

Journal of Biological Chemistry; Año: 1992 vol. 267 p. 23910 - 23915

CARLOS JOSE PIROLA; WU, S.; GREEN, J.; CAULFIELD, M.; FAGIN, J.; CLEMENS, T.

Biological Activities of N-terminal, Mid-region and C-terminal parathyroid hormone related peptides in vitro and in vivo

J. of Bone and Mineral Research; Año: 1992 vol. 7 p. 232 - 232

CARLOS JOSE PIROLA; KAMYAR, A.; WU, S.; FORRESTER, J.; CLEMENS, T.; FAGIN, J.

Parathyroid hormone related peptide: a novel vascular smooth muscle cell protein regulated by angiotensin II.

Clinical Res; Año: 1992 vol. 40 p. 1 - 1

CARLOS JOSE PIROLA; WANG, H.; WU, S.; KAMYAR, A.; FORRESTER, J.; CLEMENS, T.; FAGIN, J.

PArathyroid Hormone-Related Protein: a Functional Vascular Smooth Muscle Cell Protein Regulated by Vasoconstrictors

Circulation Suppl.I; Año: 1992 vol. 86 p. 1 - 1

KAMYAR, A.; CARLOS JOSE PIROLA; CERCEK, B.; FORRESTER, J.; FAGIN, J.

. Mitogen regulation of insulin-like growth factor binding proteins in rat vascular smooth muscle cells

Circulation Suppl.I; Año: 1992 vol. 86 p. 760 - 760

HONGO, T.; KUPFER, J.; ENOMOTO, H.; SHARIFI, B.; GIANNELLA- NETO, D.; FORRESTER, J.; SINGER, F.; HENDY, G.; CARLOS JOSE PIROLA; FAGIN, J.

Abundant Expression of Parathyroid Hormone-related Protein in Primary Rat Aortic Smooth Muscle Cells Accompanies Serum-induced Proliferation.

J. Clin. Inves; Año: 1991 vol. 88 p. 1841 - 1847

SCHEUCHER, A.; ÁLVAREZ, AZUCENA L; TORRES, N.; FINKIELMAN, SAMUEL; NAHMOD, V.; CARLOS JOSE PIROLA

Cholinergic hyperactivity in the lateral septal area of spontaneously hypertensive rats: depressor effect of hemicholinium-3 and pirenzepine.

Neuropharmacology; Año: 1991 vol. 30 p. 391 - 397

BERCOVICH, C.; FINKIELMAN, SAMUEL; NAHMOD, V.; CARLOS JOSE PIROLA

Sodium o-iodobenzoate and acid-base parameters in dogs with irreversible hemorragic shock.

Circulatory shock; Año: 1991 vol. 33 p. 63 - 67

CARLOS JOSE PIROLA; ÁLVAREZ, AZUCENA L; FINKIELMAN, SAMUEL; NAHMOD, V.

Release of acetylcholine from isolated canine renal tissue.

Am. J. Physiol; Año: 1991 vol. 29 p. 198 - 203

TORRES, N.; SCHEUCHER, A.; ÁLVAREZ, AZUCENA L; FINKIELMAN, SAMUEL; NAHMOD, V.; CARLOS JOSE PIROLA

Glucocorticoid induced hypertension in rats: role of the central muscarinic cholinergic system

Journal Endocrinology Investigation; Año: 1991 vol. 129 p. 269 - 274

FINOCCHIARO, L.; SCHEUCHER, A.; ÁLVAREZ, AZUCENA L; FINKIELMAN, SAMUEL; NAHMOD, V.; CARLOS JOSE PIROLA

Pineal hyperactivity in spontaneously hypertensive rats (SHR): muscarinic regulation of indole metabolism

Clinical science (London, England : 1979); Año: 1990 vol. 79 p. 437 - 442

CARLOS JOSE PIROLA; ÁLVAREZ, AZUCENA L; BALDA, M.; FINKIELMAN, SAMUEL; NAHMOD, V.

Biochemical evidence for cholinergic innervation in dog renal tissue.

Am. J. Physiol; Año: 1989 vol. 257 p. 1 - 1

FINOCCHIARO, L.; SCHEUCHER, A.; FINKIELMAN, SAMUEL; NAHMOD, V.; CARLOS JOSE PIROLA

Muscarinic effects on the hydroxy and methoxyindole pathway in rat pineal gland.

Journal Endocrinology Investigation; Año: 1989 vol. 123 p. 205 - 211

DABSYS, S.; BALDA, M.; CARLOS JOSE PIROLA; NAHMOD, V.; FINKIELMAN, SAMUEL

Angiotensin converting enzyme in the amygdaloid complex in neurogenic hypertension.

Clinical and Experimental Hypertension; Año: 1988 vol. A10 p. 605 - 605

CARLOS JOSE PIROLA; BALDA, M.; FINKIELMAN, SAMUEL; NAHMOD, V.

Serotonin mediates hypertensive effects of acetylcholine, norepinephrine, angiotensin II and bradykinin in the lateral septal area.

Neuropharmacology; Año: 1987 vol. 26 p. 561 - 561

SCHEUCHER, A.; CARLOS JOSE PIROLA; BALDA, M.; DABSYS, S.; ÁLVAREZ, AZUCENA L

Muscarinic M1 receptors in lateral septal area mediate vascular responses to cholinergic agonists and bradykinin: supersensitivity induced by chronic atropine treatment.

Neuropharmacology; Año: 1987 vol. 26 p. 181 - 181

BALDA, M.; CARLOS JOSE PIROLA; DABSYS, S.; FINKIELMAN, SAMUEL; NAHMOD, V.

Salarasin blocks the effects of angiotensin II and extracellular fluid saline expansion on the Na-K-ATPase inhibitor

Clinical and Experimental Hypertension; Año: 1986 vol. A p. 997 - 997

CARLOS JOSE PIROLA; BALDA, M.; ÁLVAREZ, AZUCENA L; FINKIELMAN, SAMUEL; NAHMOD, V.

Acetylcholine-bradykinin interaction in the lateral septal area of the rat brain: involvement of muscarinic receptors in cardiovascularresponses.

Neuropharmacology; Año: 1986 vol. 25 p. 1387 - 1387

CARLOS JOSE PIROLA; BALDA, M.; FINKIELMAN, SAMUEL; NAHMOD, V.

. Increase in muscarinic receptors in rat intestine by thyrotropin releasing hormone.

Life Sciences; Año: 1984 p. 1 - 1

NAHMOD, V.; BALDA, M.; CARLOS JOSE PIROLA; CARDINALI, D.

Changes in plasma aldosterone levels and renin activity after superior cervical ganglionectomy in two strain of rats.

Acta Physiol. Latinoam; Año: 1984 p. 1 - 1

CARLOS JOSE PIROLA; BALDA, M.; FINKIELMAN, SAMUEL; NAHMOD, V.

. Thyrotropin-releasing hormone increases the number of muscarinic receptors in the brain lateral septal area of the rat

Brain Research; Año: 1983 p. 1 - 1

NAHMOD, V.; BALDA, M.; CARLOS JOSE PIROLA; FINKIELMAN, SAMUEL; GEJMAN, P.; CARDINALI, D.

Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme.

Brain Research; Año: 1982 p. 1 - 1

BENARROCH, E.; CARLOS JOSE PIROLA; ÁLVAREZ, AZUCENA L; NAHMOD, V.

Serotoninergic and noradrenergic mechanisms in the cardiovascular effects of angiotensin II into the anterior hypothalamic preoptic region of the rats.

Neuropharmacology; Año: 1981 p. 1 - 1

ÁLVAREZ, AZUCENA L; CARLOS JOSE PIROLA; BENARROCH, E.; FINKIELMAN, SAMUEL; NAHMOD, V.

Muscarinic receptor involvement in the electrolytic changes of kidney tubular cells elicited by bradykinin and cholinergic agonists.

IRCS Medical Science: Biochemistry, Cardiovascular System, Drug, Metabolism; Año: 1980 vol. 8 p. 214 - 214

CARLOS JOSE PIROLA; CRISCUOLO, M.; ÁLVAREZ, AZUCENA L; BENARROCH, E.; FINKIELMAN, SAMUEL; NAHMOD, V.

Cholinergic mechanisms involvedin the natriuretic effect of furosemide.

IRCS Medical Science: Cardiovascular System, Kidney and Urinary Systems, Ph; Año: 1980 p. 1 - 1

BENARROCH, E.; CARLOS JOSE PIROLA; NAHMOD, V.

Cholinergic mechanisms involved in the pressor action of bradykinin in the lateral septal area

IRCS Medical Science: Cardiovascular System, Pharmacology, and Nervous Syst; Año: 1980 vol. 8 p. 83 - 83

NAHMOD, V.; FINKIELMAN, SAMUEL; BENARROCH, E.; CARLOS JOSE PIROLA

Angiotensin regulates release and synthesis of serotonin.

Science; Año: 1978 vol. 202 p. 1091 - 1091