INVESTIGADORES
MORELLI Laura
congresos y reuniones científicas
NOVACK, GISELA V.; GALEANO, PABLO; CASTAÑO EM; CUELLO, A CLAUDIO; MORELLI LAURA
Mitochondrial complex I: stabilization and activity in a rat model of cerebral amyloidosis.
LXVIII Reunión Anual de la Sociedad Argentina de Investigación Clínica (SAIC)
Lugar: Mar del Plata; Año: 2023;
CAMPANELLI, L; GALEANO P; GONZALEZ-JIMENEZ, A; RODRÍGUEZ DE FONSECA, FERNANDO; CUELLO, A CLAUDIO; CASTAÑO EM; MORELLI LAURA
Multiomics analysis of the metabolome and microbiota in a rat model of cerebral amyloidosis
ISN-ASN Meeting 2023
Lugar: Porto; Año: 2023;
CAMPUZZANO K; DO CARMO, S; PIROMALLI GIRADO, D; BEKINSCHTEIN, P; CASTAÑO EM; SANTIN, L.; CUELLO, A.C.; MORELLI L; GALEANO, P.
Environmental enrichment rescues pattern separation deficit in a rat transgenic model of Alzheimer's‐like brain amyloidosis
XXXVIII Congreso de la Sociedad Argentina de Neurociencias (SAN)
Lugar: San Luis; Año: 2023;
MORELLI LAURA
Mitochondrial Supercomplexes: Organization and Dysregulation in a rat model of cerebral amyloidosis
Current Trends in Redox Biochemistry and Medicine Symposium
Lugar: Montevideo; Año: 2023;
NOVACK, GISELA V.; GALEANO P; CASTAÑO E.M; CUELLO, A CLAUDIO; MORELLI LAURA
Assembly of mitochondrial supercomplexes in the brain of a rat model of Alzheimer
Bi Annual Congress ASN 2022
Lugar: ROANOKE; Año: 2022;
CAMPANELLI, L; GALEANO, P.; CASTANO E.M; GONZALEZ-JIMENEZ, A; RODRIGUEZ-FONSECA, F; CUELLO, A CLAUDIO; MORELLI, L
Association of microbiome, metabolome and cognitive performance, an exploratory multiomics approach in a rat model of cerebral amyloidosis
LVIII Annual Meeting of the Argentine Society for Biochemistry and Molecular Biology
Lugar: Mendoza; Año: 2022;
NOVACK, GISELA V.; GALEANO, P.; CASTANO E.M; MORELLI L
ENSAMBALDO DE COMPLEJOS MITOCONDRIALES EN CEREBRO DE RATAS QUE MODELAN ALZHEIMER
XXIII Jornadas Anuales de la Sociedad Argentina de Biología
Lugar: CABA; Año: 2021;
PRESTIA, FEDERICO A.; GALEANO, P.; DALMASSO MC; COSTA, L.; CASTAñO E.M; POLITIS, DANIEL GUSTAVO; KOCHEN, SILVIA; BRUSCO, LI; MORELLI L
Pilot human study to define the impact of vascular and Inflammatory risk factors in Alzheimer?s disease
ISN-ASN MEETING 2019
Lugar: Montreal; Año: 2019;
GALEANO P; DALMASSO MC; PRESTIA, F.A.; CASTAñO E.M; CUELLO, C; SANTIN, L.; MORELLI, L
Adult hippocampal neurogenesis impairment at pre‐plaque stage in a transgenic rat model of Alzheimer's‐like amyloid pathology
ISN-ASN Meeting 2019
Lugar: Montreal; Año: 2019;
RUIZ VIROGA, V.; GALEANO P; MORELLI L; LAGOS, P.
Efectos de la administración intra-hipocampal de la hormona concentradora de melanina (MCH) sobre la memoria en ratas
Sociedad Uruguaya de Biociencias
Lugar: Montevideo; Año: 2019;
DALMASSO MC; BRUSCO, LI; OLIVAR N; MORELLI L
Rare Coding Variants in PLCG2, ABI3, and TREM2 Are Associated with Alzheimer Disease in the Argentinian Population
AAIC 2018 Chicago-USA
Año: 2018;
MORELLI L
Genetic Consortium in LATAM: Strengths, Weaknesses, Opportunities, and Threats.
3rd Annual Global Brain Health Institute (GBHI) Conference
Año: 2018;
MARTINO ADAMI PV; CASTAÑO, EM; CUELLO, C; HAJNÓCZKY, G.; MORELLI L
MOLECULAR MECHANISMS INVOLVED IN EARLY NEURONAL BIOENERGETIC DYSFUNCTION
AAIC Satellite Symposium
Año: 2018;
FERNANDEZ SUAREZ, M.; RUSSO, G.; DALMASSO MC; OLIVAR, N; RAMIREZ, A; MORELLI, L.; BRUSCO, LI
CASE REPORT: HETEROZYGOUS APP A713T MUTATION CARRIER WITH INFLAMMATORYAMYLOID ANGIOPATHYAND FAMILY HISTORY OF AD: FIRST CASE IN ARGENTINA
AAIC 2017 London
Lugar: Londres; Año: 2017;
MARTINO ADAMI PV; CASTAÑO E.M; CUELLO, C; HAJNÓCZKY, G.; MORELLI L
Relaxed mitochondria-endoplasmic reticulum connections and amyloid β accumulation: a common neurotoxic pathway?
Conference
Año: 2017;
MORELLI, L.
Alzheimer Disease: A complex Multifactorial Disorder
4th ISN Latinamerican School of Advanced Neurochemistry: ?Brain Pathologies and Natural Products?
Año: 2017;
MARTINO ADAMI PV; CASTAÑO EM; CUELLO, C; HAJNÓCZKY, G.; MORELLI, L.
Understanding risk factors for Alzheimer disease: interplay of neurovascular coupling, neuroinflammation and cognitive performance
The role of glial cells in health and disease of the nervous system: clinical and basic science working together
Año: 2017;
MARTINO ADAMI PV; CASTAÑO E.M; CUELLO, C; HAJNÓCZKY, G.; MORELLI, L.
Can ER-Mitochondria coupling, bioenergetics and accumulation of Aβ be linked together in a common and early pathogenic pathway in Alzheimer ?
Alexander von Humboldt Kolleg Current Advances on Neurodegeneration: from Molecular Biology to Translational Medicine
Año: 2017;
GUITART ME; ROSATO-SIRI V; MARTINO ADAMI PV; VERSTRATEN S; MORELLI L; PASQUINI, J.M.
Oligodendrocytes maturation and metabolic profile upon iron deficiency.
Reunion de Sociedades Conjuntas
Año: 2017;
CACERES L; PAZ M; MARTINO ADAMI PV; OJEDA D; GARCES M; CALABRO V; TASSAT D.; MORELLI L; ALVAREZ S; GONZALEZ MAGLIO D; MARCHINI T; EVELSON, P
THE ROLE OF MITOCHONDRIA IN THE OXIDATIVE RESPONSE OF RAW 264.7 MURINE MACROPHAGES EXPOSED TO AIR POLLUTION PARTICULATE MATTER
Reunion de Sociedades Conjuntas
Año: 2017;
MARTINO ADAMI PV; ROTONDARO, MC; CASTAÑO, E.M.; HAJNÓCZKY, G.; MORELLI, L.
Relaxed mitochondria-endoplasmic reticulum connections and amyloid β accumulation: a common neurotoxic pathway?
Reunion de Sociedades Conjuntas
Año: 2017;
PRESTIA, F.A.; MARTINO ADAMI PV; GALEANO P; CUELLO, C; CASTAÑO, E.M.; MORELLI L
Platelets bioenergetics as a potential biomarker for Alzheimer?s disease.
Reunion de Sociedades Conjuntas
Año: 2017;
BELFIORI-CARRASCO, LAUTARO F.; MARCORA, MARÍA S.; BOCAI, NADIA I.; CERINAI, MF; MORELLI L; CASTAÑO E.M
A novel genetic screen identifies modifiers of agedependent amyloid b toxicity in the drosophila brain
26th Biennial Meeting of the International Society for Neurochemistry (ISN).
Lugar: Paris; Año: 2017;
MARTINO ADAMI PV; BARRANTES, FJ; ROTONDARO, MC; CASTAÑO E.M; HAJNÓCZKY, G.; MORELLI, L.
Altered neuronal endoplasmic reticulum-mitochondria coupling in a transgenic rat model of Alzheimer?s disease
26th Biennial Meeting of the International Society for Neurochemistry (ISN).
Año: 2017;
DALMASSO MC; ARAN, M.; FERRARI CC; SMAL, C.; CASTAÑO EM; CUELLO C; MORELLI L
Untargeted 1 h-NMR spectrometry to detect central and systemic metabolic changes in a rat model of early Alzheimer?s disease
26th Biennial Meeting of the International Society for Neurochemistry (ISN).
Lugar: Paris; Año: 2017;
FUCHS, F.; MORELLI, L.; KADENER, S.; GROSSHANS, H.; DE LA MATA, M.
DIFFERENTIAL ROLE OF CIRCULAR AND LINEAR TARGET RNAS ON MICRORNA STABILITY.
Reunion de Sociedades Conjuntas
Año: 2017;
GALEANO P; LEAL MC; FERRARI CC; DALMASSO MC; MARTINO ADAMI PV; FARÍAS MI; CASTAÑO EM; PITOSSI F ; MORELLI L
Adult hippocampal Notch activation impairs Aβ clearance and cognition in a rat model of Alzheimer
SAIB - 5 2 th Annual Meeting Argentine Society for Biochemistry and Molecular Biology L I I Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular
Lugar: Cordoba; Año: 2016;
MARTINO ADAMI PV; GALEANO P; WALLINGER ML; RABOSSI A; RADI R; GEVORKIAN G; CUELLO C; MORELLI L
METABOLIC DYSFUNCTION WORSENS COGNITION AND NEURONAL RESILIENCE IN A RAT MODEL OF EARLY ALZHEIMER
SAIB - 5 2 th Annual Meeting Argentine Society for Biochemistry and Molecular Biology L I I Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular
Lugar: Cordoba; Año: 2016;
MORELLI L; MARCORA, MS; BOCAI N; CASTAÑO EM
MODELING ALZHEIMER'S DISEASE IN TRANSGENIC ANIMALS
25th ISN-APSN Joint Biennial Meeting in conjunction with ANS
Año: 2015;
MARTINO ADAMI P; QUIJANO C; MAGNANI, N; GALEANO, P.; CASSINA A; LEAL MARIA C.; CUELLO C; MORELLI L
BRAIN BIOENERGETICS AND COGNITIVE PERFORMANCE IN A TRANSGENIC RAT MODEL OF EARLY ALZHEIMER'S DISEASE
51 Annual Meeting SAIB
Año: 2015;
DALMASSO C; MUCHNIK C; ACION L ; KELMANSKY D; OLIVAR N; BRUSCO LI; MORELLI L
SINGLE NUCLEOTIDE POLYMORPHISMS (SNPS) ASSOCIATED TO ALZHEIMER?S DISEASE IN THE ARGENTINE POPULATION
51 Annual Meeting SAIB
Año: 2015;
MORELLI LAURA
Impact of pyrroloquinoline quinone on synaptic bioenergetic status, cognition and behavior in a transgenic rat model of early Alzheimer?s disease
Dementia 2014
Año: 2014;
MORELLI, LAURA
Impact of Brain Bioenergetic Status on Cognition and Behavior in a Rat Model Mimicking Early Alzheimer
International Symposium: Mitochondria and Cell Metabolism
Año: 2014;
MORELLI L
Use of Genetic Variation as Biomarkers for Alzheimers Disease
5to- LACIM 2013- Encuentro Latinoamericano sobre Deterioro Cognitivo
Año: 2013;
GALEANO, P.; MARTINO ADAMI, P.; BLANCO CALVO, E.; LOGICA TORNATORE, T.; CAPANI, F.; CASTAÑO, E.M.; MORELLI, L
Early behavioral abnormalities are independent of extracellular Aâ accumulation in a new transgenic rat model of Alzheimer's disease
15? Congreso Nacional de la Sociedad Española de Neurociencia; 2013
Lugar: Oviedo; Año: 2013;
MORELLI L
Strategies on Biomarkers to Diagnose Alzheimer?s Disease.
ISN ASN 24th Biennial Joint Meeting
Año: 2013;
MARTINO ADAMI P; MAGNANI, N; GALEANO, P.; ROTONDARO C; CUELLO C; EVELSON, P; CASTAñO E.M; MORELLI L
Premature bioenergetic and cognitive defects in a rat model of presymptomatic Alzheimer disease
Reunion Anual SAIB 2013
Año: 2013;
MARTINO ADAMI P; MAGNANI, N; GALEANO, P.; CUELLO C; EVELSON, P; CASTAñO E.M; MORELLI L
Early mitochondrial dysfunction and behavioral alterations in a new transgenic rat model of presymptomatic Alzheimer disease.
VIII Meeting of the Society for Free Radical Biology and Medicine, South American Group.
Año: 2013;
BRUSCO LI; OLIVAR N; MUCHNIK C; AZURMENDI, P; DALMASSO C; MORELLI, L
?Selección de marcadores genéticos para la enfermedad de Alzheimer en población argentina y construcción de un patrón de riesgo con utilidad diagnóstica
nano-mercosur 2013
Año: 2013;
MARCORA, MS; MORELLI L
Modelado de proteinopatías cerebrales humanas en animales transgénicos
XIV CONGRESO ARGENTINO DE NEUROPSIQUIATRÍA y Neurociencia Cognitiva 10° CONGRESO LATINOAMERICANO DE NEUROPSIQUIATRÍA XV Jornadas de la Enfermedad de Alzheimer IV Jornadas de Neurología Cognitiva y Esclerosis Múltiple
Año: 2012;
LEAL M.C; MARINO BUSJLE,, C; MAGNANI, N; EVELSON, P; CASTAÑO E.M; MORELLI L
The human IDE is a downstream target gene of mitochondrial biogenesis pathway
5th Special Conference-ISN
Lugar: Buenos Aires; Año: 2012;
MORELLI L
Human Insulin-degrading enzyme is a target of mitochondrial biogenesis pathway and modulates mitochondrial AÒ accumulation.
Nuerodegeneration Conference
Lugar: Cancun; Año: 2012;
FERNANDEZ-GAMBA A.; LEAL M.C; DITULLIO M; ROHER A.E; MORELLI, L; CASTAÑO, E.M.
La retracción reversible de procesos en oligodendrocitos inducida por estres oxidativo no-letal está mediada por la fosforilación de CRMP-2 en un sitioomotes the reversible retraction of oligodendrocyte processes in response to non-lethal oxidative stress
LVI Reunión Anual de la SAIC
Lugar: Mar del Plata; Año: 2011;
MORELLI L; SURACE EI; LEAL MC; HOLGADO MP; FERRARI CC; TARELLI R; PITOSSI F; WISNIEWSKI T; CASTAÑO EM
Notch signaling impacts on amyloid β metabolism by modulating IDE and BACE1.
International Conference of Alzheimer`s Disease & Related Disorders
Lugar: Hawaii; Año: 2010;
CASTAÑO EM; SURACE EI; LEAL M.C; MORELLI L
Keeping the balance of amyloid β with proteases on both sides of the equation
XLVI Reunión Anual de la SAIB
Lugar: Puerto Madryn; Año: 2010;
MORELLI LAURA
Plegamiento anormal de proteínas y demencias: Mecanismos moleculares que conducen a la neurodegeneración
LV Reunión Científica Anual de la Sociedad Argentina de Investigación Clínica (SAIC).
Lugar: Mar del Plata; Año: 2010;
FERNANDEZ-GAMBA AGATA; WILLIAMS AISHA; LEAL MC; DI TULLIO, M; ROHER ALEX; MORELLI LAURA; CASTAÑO EM
Dynamic changes in oligodendrocytes induced by oxidative stress and amyloid-beta.
International Workshop on Nanomaterials and Functional Materials
Lugar: Campinas-Brasil; Año: 2009;
LEAL MARIA; SURACE EZEQUIEL; BULLOJ AYELEN; GHIGULLY M; CATAÑO EDUARDO; MORELLI LAURA
Mitogen-activated protein kinase pathways play a critical role in hypoxia-induced Insulin Degrading Enzyme expression and activity in astrocytes.
International Meeting American Society for Neuroscience
Lugar: San Antonio, USA; Año: 2008;
LEAL MARIA; BULLOJ AYELEN; XU HUAXI; CASTAÑO EDUARDO; MORELLI LAURA
Exosome-dependent Trafficking Of Insulin Degrading Enzyme Modulates Amyloid Beta Clearance.
International Conference of Alzheimer`s disease and related disorders (ICAD)
Lugar: Chicago, USA; Año: 2008;
DI TULLIO MATIAS; FERNANDEZ-GAMBA AGATA; LLOVERA RAMIRO; MORELLI LAURA; CASTAÑO EDUARDO
Insulin-degrading enzyme: a possible dead-end chaperone for amyloid peptides.
International conferences of Alzheimer`s disease and related disorders
Lugar: Chicago, USA.; Año: 2008;
SURACE EI; GHIGULLY M; LEAL MC; BULLOJ A; CASTAÑO EM; MORELLI L
Transcriptional expression and enzymatic activity of Insulin-degrading enzyme is modulated by genetic and environmental factors.
International Society for Neurochemistry
Lugar: Cancu;n, Mexico; Año: 2007;
DORFMAN VB; PASQUINI LA; RUIDAVETS M; CASTAÑO EM; MORELLI L
DIFERENCIAS EN EL DEPÓSITO CORTICAL DE LA ENZIMA DEGRADADORA DE INSULINA EN CEREBROS CON ENFERMEDAD DE ALZHEIMER FAMILIAR Y ESPORÁDICA
LII REUNION CIENTIFICA ANUAL (SAIC)
Lugar: Mar del Plata; Año: 2007;
BULLOJ A; LEAL MC; XU H; CASTAÑO EM; MORELLI L
Exosome-dependent trafficking of insulin degrading enzyme (IDE) modulates amyloid ß (Aß) degradation.
SAIB 43th Annual Meeting.
Lugar: Mar del Plata; Año: 2007;
LLOVERA RE; DE TULIO M; ALONSO L; PRAT GAY G; MORELLI L; CASTAÑO EM
THE CATALYTIC DOMAIN OF INSULIN-DEGRADING ENZYME FORMS A HIGHLY STABLE COMPLEX WITH AMYLOID ?Ò PEPTIDE
SAIB 43th Annual Meeting
Lugar: Mar del Plata; Año: 2007;
DE TULIO M; LLOVERA RE; MORELLI L; CASTAÑO EM
Characterization of a stable complex between inactive insulin-degrading enzyme with Aß peptide.
SAIB 43th Annual Meeting
Lugar: Mar del Plata; Año: 2007;
SURACE EI; LEAL MC; BULLOJ A; CASTAñO EM; MORELLI L
Transcriptional regulation of insulin-degrading enzyme (IDE): Possible role of hypoxia and Notch.
SAIB 43th Annual Meeting.
Lugar: Mar del Plata, Argentina; Año: 2007;
LEAL MC; DORFMAN VB; FERNANDEZ-GAMBA A; FRANGIONE B; WISNIEWSKI T; CASTAÑO EM; SIGURDDSON E; MORELLI L
FIBRILLAR AB TRIGGERS INSULIN DEGRADING ENZYME (IDE) OVER-EXPRESSION BY GLIAL CELLS IN OLD Tg2576 MICE.
International Conference of Alzheimer`s Disease & Related Disorders
Lugar: Madrid, España; Año: 2006;
BULLOJ A; LEAL MC; MORELLI L; XU H; CASTAÑO EM
Active Insulin Degrading Enzyme in lipid rafts: relevance for Aß degradation in the brain.
International Conference of Alzheimer`s Disease & Related Disorders
Lugar: Madrid, España; Año: 2006;
BULLOJ A; LEAL MC; CASTAÑO EM; XU H; MORELLI L
Active Insulin Degrading Enzyme in lipid rafts: Relevance for Aâ degradation in the brain.
The Second ISN Special Neurochemistry Conference on Neural Glycoproteins and Glycolipids.
Lugar: Antigua; Año: 2006;
LOVERA, RE; ALONSO, L; FERNANDEZ-GAMBA,A; DI TULLIO, M; PRAT-GAY, G; MORELLI, L; CASTAÑO, EM
12. The formation of stable complex between Aß and insulin-degrading enzyme: a possible trans-acting pathway of amyloid self-propagation in the brain.
PABMB 10th Congress, SAIB 41th Annual Meeting and SAN 20th Annual Meeting
Lugar: Pinamar, Argentina; Año: 2005;
LEAL, MC; GHIGULLY, M; CASTAÑO, EM; MORELLI, L
Insulin degrading enzyme as a downstream target of stress and growth factors signaling cascades: implications for Alzheimer`s disease interventions
PABMB 10th Congress, SAIB 41th Annual Meetin and SAN 20th Annual Meeting.
Lugar: Pinamar, Argentina; Año: 2005;
BULLOJ, A; LEAL, MC; CASTAÑO, EM; XU,H; MORELLI,L
Insulin degrading enzyme: the secretory pathway implicated in the clearance of amyloid ß.
PABMB 10th Congress, SAIB 41th Annual Meeting and SAN 20th Annual Meeting.
Lugar: Pinamar, Argentina; Año: 2005;
DORFMAN, V; CASTAÑO, EM; MORELLI, L
Insulin degrading enzyme over-expression is associated with amyloid ß plaque development.
PABMB 10th Congress, SAIB 41th Annual Meetin and SAN 20th Annual Meeting.
Lugar: Pinamar, Argentina; Año: 2005;
MORELLI, L; LLOVERA, RE; FRANGINE, B; GHISO, J; CASTAÑO, EM
Insulin degrading enzyme from human brain microvessels degrades amyloid β and its Flemish, Dutch and Italian vasculotropic variants. Laura Morelli, Ramiro E. Llovera, Blas Frangione, Jorge Ghiso, Eduardo M. Castaño.
Annual Meeting Alzheimer Disease Association.
Lugar: Philadelphia, USA; Año: 2004;
MORELLI,L.; LOVERA, RE.; FRANGIONE, B.; GHISO, J.; CASTAÑO, EM
Proteolysis of the ABri and ADan peptides by insulin degrading enzyme.
Annual Meeting Society for Neuroscience
Lugar: San Diego; Año: 2004;
LEAL, MC; DORFMAN, V; MATHOV, I; CASTAÑO, EM; MORELLI, L
La proteólisis insuficiente del péptido Aß por la enzima degradadora de insulina (EDI) como posible mecanismo involucrado en enfermedad de Alzheimer
Congreso de Sociedades Conjuntas
Lugar: Mar del Plata, Argentina; Año: 2004;
