IDEHU 05542
INSTITUTO DE ESTUDIOS DE LA INMUNIDAD HUMORAL PROF. RICARDO A. MARGNI
Unidad Ejecutora - UE
artículos
Título:
The rs1801278 G>A polymorphism of IRS-1 is associated with metabolic syndrome in healthy nondiabetic men. Modulation by cigarette smoking status
Autor/es:
PÉREZ MS; TELLECHEA ML; ARANGUREN F; TAVERNA MJ; RODRÍGUEZ RG; MEROÑO T; BRITES F; POSKUS E; FRECHTEL GD
Revista:
DIABETES RESEARCH AND CLINICAL PRACTICE
Editorial:
ELSEVIER IRELAND LTD
Referencias:
Año: 2011
ISSN:
0168-8227
Resumen:
Aims To explore associations between IRS-1 rs1801278 G > A polymorphism and metabolic syndrome (MS). Methods rs1801278 G > A was genotyped in 610 healthy Argentinian men. Results GA carriers had lower risk of MS (OR = 0.52, P = 0.045), particularly among smokers (OR = 0.10, P = 0.006). Conclusions rs1801278 GA carriers had lower risk of MS, especially among smokers.
