INVESTIGADORES
MORELLI Laura
artículos
DALMASSO, MARIA CAROLINA; DE ROJAS, ITZIAR; OLIVAR, NATIVIDAD; MUCHNIK, CAROLINA; ANGEL, BÁRBARA; GLOGER, SERGIO; SANCHEZ ABALOS, MARIANA SOLEDAD; CHACÓN, MARÍA VICTORIA; ARÁNGUIZ, RAFAEL; ORELLANA, PAULINA; CUESTA, CAROLINA; GALEANO, PABLO; CAMPANELLI, LORENZO; NOVACK, GISELA VANINA; MARTINEZ, LUIS EDUARDO; MEDEL, NANCY; LISSO, JULIETA; SEVILLANO, ZULMA; IRURETA, NICOLÁS; CASTAÑO, EDUARDO MIGUEL; MONTRREAL, LAURA; THOENES, MICHAELA; HANSES, CLAUDIA; HEILMANN-HEIMBACH, STEFANIE; KAIRIYAMA, CLAUDIA; MINTZ, INÉS; VILLELLA, IVANA; RUEDA, FABIANA; ROMERO, AMANDA; WUKITSEVITS, NANCY; QUIROGA, IVANA; GONA, CRISTIAN; LAMBERT, JEAN-CHARLES; SOLIS, PATRICIA; POLITIS, DANIEL GUSTAVO; MANGONE, CARLOS ALBERTO; GONZALEZ-BILLAULT, CHRISTIAN; BOADA, MERCÈ; TÀRRAGA, LLUÍS; SLACHEVSKY, ANDREA; ALBALA, CECILIA; FUENTES, PATRICIO; KOCHEN, SILVIA; BRUSCO, LUIS IGNACIO; RUIZ, AGUSTÍN; MORELLI, LAURA; RAMÍREZ, ALFREDO
The first genome-wide association study in the Argentinian and Chilean populations identifies shared genetics with Europeans in Alzheimer's disease
ALZHEIMERS & DEMENTIA; Año: 2023
RUIZ-VIROGA, VICENTE; DE CEGLIA, MARIALUISA; MORELLI, LAURA; CASTAÑO, EDUARDO M.; CALVO, EDUARDO BLANCO; SUÁREZ, JUAN; RODRÍGUEZ DE FONSECA, FERNANDO; GALEANO, PABLO; LAGOS, PATRICIA
Acute intrahippocampal administration of melanin-concentrating hormone impairs memory consolidation and decreases the expression of MCHR-1 and TrkB receptors
PROGRESS OF NEUROPSYCHOPHARMACOLOGY AND BIOLOGICAL PSYCHIATRY; Año: 2023 vol. 123
DALMASSO MC; ARAN, M.; GALEANO P; PERIN S; GIAVALISCO P; ADAMI, PAMELA MARTINO; NOVACK, GISELA V.; CASTANO E.M; CUELLO, A.C.; SCHERER M; MAIER W; WAGNER M; RIEDEL-HELLER S; RAMIREZ, A; MORELLI L
Nicotinamide as potential biomarker for Alzheimer’s disease: a translational study based on metabolomics
Front. Mol. Biosci. - Metabolomics; Año: 2023
GALEANO P; DI CEGLIA ML; MASTOGIOVANNI M; CAMPANELLI, L; MEDINA VERA D; CAMPOLO N; NOVACK, GISELA V.; ROSELL VALLE C; SUAREZ J; AICARDO A; CAMPUZZANO K; CASTAÑO E.M; DO CARMO, S; CUELLO, A CLAUDIO; BARTESAGHI S; RADI R; RODRÍGUEZ DE FONSECA, FERNANDO; MORELLI L
The Effect of Fat Intake with Increased Omega-6-to-Omega-3 Polyunsaturated Fatty Acid Ratio in Animal Models of Early and Late Alzheimer’s Disease-like Pathogenesis
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; Lugar: Basel; Año: 2023
HORIMOTO, ANDREA R.V.R.; BOYKEN, LISA A.; BLUE, ELIZABETH E.; GRINDE, KELSEY E.; NAFIKOV, RAFAEL A.; SOHI, HARKIRAT K.; NATO, ALEJANDRO Q.; BIS, JOSHUA C.; BRUSCO, LUIS I.; MORELLI, LAURA; RAMIREZ, ALFREDO; DALMASSO, MARIA CAROLINA; TEMPLE, SETH; SATIZABAL, CLAUDIA; BROWNING, SHARON R.; SESHADRI, SUDHA; WIJSMAN, ELLEN M.; THORNTON, TIMOTHY A.
Admixture mapping implicates 13q33.3 as ancestry-of-origin locus for Alzheimer disease in Hispanic and Latino populations
Human Genetics and Genomics Advances; Lugar: Amsterdam; Año: 2023 vol. 4
ROSATO-SIRI V; GUITART ME; ADAMI, PAMELA MARTINO; MORELLI L; VERSTRAETEN S; CORREALE J; PASQUINI, J.M.
Glial cell metabolic profile upon iron deficiency: oligodendroglial and astroglial casualties of bioenergetic adjustments
MOLECULAR NEUROBIOLOGY; Lugar: Oregon; Año: 2023
BELLENGUEZ*; KÜÇÜKALI*; JANSEN*; KLEINEIDAM*; MORENO-GRAU*, ; DALMASSO C; MORELLI LAURA; RAMIREZ, ALFREDO; LAMBERT, JEAN-CHARLES
New insights on the genetic etiology of Alzheimer?s and related dementia.
NATURE GENETICS; Lugar: Londres; Año: 2022
NAVAS GUIMARAES, MARIÁ EUGENIA; LOPEZ-BLANCO, ROI; CORREA, JUAN; FERNANDEZ-VILLAMARIN, MARCOS; BISTUÉ, MARIÁ BEATRIZ; MARTINO-ADAMI, PAMELA; MORELLI, LAURA; KUMAR, VIJAY; WEMPE, MICHAEL F.; CUELLO, A.C.; FERNANDEZ-MEGIA, EDUARDO; BRUNO, MARTIN A.
Liver X Receptor Activation with an Intranasal Polymer Therapeutic Prevents Cognitive Decline without Altering Lipid Levels
ACS NANO; Año: 2021
PARRA, MARIO ALFREDO; BAEZ, SANDRA; SEDEÑO, LUCAS; GONZALEZ CAMPO, CECILIA; MORELLI, LAURA; IBANEZ, AGUSTIN
Dementia in Latin America: Paving the way toward a regional action plan
ALZHEIMERS & DEMENTIA; Año: 2021
DE ROJAS, I.; RUIZ, A.; MORELLI L; RAMIREZ, A
Common variants in Alzheimer?s disease and risk stratification by polygenic risk scores
NATURE COMMUNICATIONS; Año: 2021
CACERES L; PAZ M; GARCES M; CALABRO V; MAGNANI, N; MARTINEVSKY, M.; ADAMI, PAMELA MARTINO; CALTANA, L; TASAT, D.; MORELLI L; TRIPODI, V; VALACCHI, G; ALVAREZ S; GONZALEZ MAGLIO D; MARCHINI, T; EVELSON, P
NADPH oxidase and mitochondria are relevant sources of superoxide anion in the oxin ammatory response of macrophages exposed to airborne particulate matter
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY; Lugar: Amsterdam; Año: 2020
NOVACK, GISELA V.; GALEANO, PABLO; CASTAÑO, EDUARDO M.; MORELLI, LAURA
Mitochondrial Supercomplexes: Physiological Organization and Dysregulation in Age-Related Neurodegenerative Disorders
Frontiers in Endocrinology; Año: 2020 vol. 11
BOCAI, NADIA I.; MARCORA, MARÍA S.; BELFIORI-CARRASCO, LAUTARO F.; MORELLI, LAURA; CASTAÑO, EDUARDO M.
Endoplasmic Reticulum Stress in Tauopathies: Contrasting Human Brain Pathology with Cellular and Animal Models
JOURNAL OF ALZHEIMER'S DISEASE; Año: 2019 vol. 68 p. 439 - 458
DALMASSO, MARIA CAROLINA; BRUSCO, LUIS IGNACIO; OLIVAR, NATIVIDAD; MUCHNIK, CAROLINA; HANSES, CLAUDIA; MILZ, ESTHER; BECKER, JULIAN; HEILMANN-HEIMBACH, STEFANIE; HOFFMANN, PER; PRESTIA, FEDERICO A.; GALEANO, PABLO; AVALOS, MARIANA SOLEDAD SANCHEZ; MARTINEZ, LUIS EDUARDO; CARULLA, MARIANA ESTELA; AZURMENDI, PABLO JAVIER; LIBERCZUK, CYNTHIA; FEZZA, CRISTINA; SAMPAÑO, MARCELO; FIERENS, MARIA; JEMAR, GUILLERMO; SOLIS, PATRICIA; MEDEL, NANCY; LISSO, JULIETA; SEVILLANO, ZULMA; BOSCO, PAOLO; BOSSÙ, PAOLA; SPALLETTA, GIANFRANCO; GALIMBERTI, DANIELA; MANCUSO, MICHELANGELO; NACMIAS, BENEDETTA; SORBI, SANDRO; MECOCCI, PATRIZIA; PILOTTO, ALBERTO; CAFFARRA, PAOLO; PANZA, FRANCESCO; BULLIDO, MARIA; CLARIMON, JORDI; SÁNCHEZ-JUAN, PASCUAL; COTO, ELIECER; SANCHEZ-GARCIA, FLORENTINO; GRAFF, CAROLINE; INGELSSON, MARTIN; BELLENGUEZ, CÉLINE; CASTAÑO, EDUARDO MIGUEL; KAIRIYAMA, CLAUDIA; POLITIS, DANIEL GUSTAVO; KOCHEN, SILVIA; SCARO, HORACIO; MAIER, WOLFGANG; JESSEN, FRANK; MANGONE, CARLOS ALBERTO; LAMBERT, JEAN-CHARLES; MORELLI,
Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer’s disease
TRANSLATIONAL PSYCHIATRY; Año: 2019 vol. 9
FERNANDEZ SUAREZ, M.; BRUSCO, LI; DALMASSO MC; OLIVAR N; MORELLI L; RUSSO, G.
Heterozygous app a713t mutation carrier with inflammatoy amyloid angiopathy and family history of alzheimer´s disease. First case in Argentina
Journal of neurology and Stroke; Año: 2019
MARTINO ADAMI, PAMELA V.; NICHTOVÁ, ZUZANA; WEAVER, DAVID B.; BARTOK, ADAM; WISNIEWSKI, THOMAS; JONES, DREW R.; DO CARMO, SONIA; CASTAÑO, EDUARDO M.; CUELLO, A CLAUDIO; HAJNÓCZKY, GYÖRGY; MORELLI, LAURA
Perturbed mitochondria-ER contacts in live neurons that model the amyloid pathology of Alzheimer's disease
Journal of cell science; Año: 2019 vol. 132
SANMARCO, LILIANA MARÍA; EBERHARDT, NATALIA; BERGERO, GASTÓN; QUEBRADA PALACIO, LUZ PIEDAD; ADAMI, PAMELA MARTINO; VISCONTI, LAURA MARINA; MINGUEZ, ÁNGEL RAMÓN; HERNÁNDEZ-VASQUEZ, YOLANDA; CARRERA SILVA, EUGENIO ANTONIO; MORELLI, LAURA; POSTAN, MIRIAM; AOKI, MARIA PILAR
Monocyte glycolysis determines CD8+ T cell functionality in human Chagas disease
JCI Insight; Año: 2019 vol. 4
PRESTIA, F.A.; GALEANO, P.; MARTINO ADAMI PV; DO CARMO, S; CASTAÑO E.M; CUELLO, C; MORELLI L
Platelets bioenergetics screening reflects the impact of brain Aβ plaque accumulation in a rat model of Alzheimer
NEUROCHEMICAL RESEARCH; Lugar: New York; Año: 2019
GALEANO, P.; LEAL M.C; FERRARI CC; DALMASSO MC; MARTINO ADAMI PV; FARÍAS MI; CASABONA, JC; PUNTEL, M; DO CARMO, S; SMAL, C.; ARAN, M.; CASTAÑO E.M; PITOSSI F; CUELLO, C; MORELLI, L.
Chronic hippocampal expression of Notch intracellular domain induces vascular thickening, reduces glucose availability and exacerbates spatial memory deficits in a rat model of early Alzheimer
MOLECULAR NEUROBIOLOGY; Lugar: Oregon; Año: 2018
MARTINO ADAMI P; GALEANO, P.; WALLINGER, ML; QUIJANO C; RABOSSI, A; PAGANO, ES; OLIVAR, N; REYES TOSO, C; CARDINALE, D; BRUSCO LI; DO CARMO, S; RADI, R; GEVORKIAN, G; CASTAÑO, E.M.; CUELLO, C; MORELLI, L
Worsening of memory deficit induced by energy-dense diet in a rat model of early-Alzheimer's disease is associated to neurotoxic Aβ species and independent of neuroinflammation
BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE; Lugar: Amsterdam; Año: 2017
BELFIORE CARRASCO; MARCORA, MS; BOCAI N; CERINAI, MF; MORELLI L; CASTAÑO E.M
A Novel Genetic Screen Identifies Modifiers of Age-Dependent Amyloid b Toxicity in the Drosophila Brain
Frontiers in Aging Neuroscience; Año: 2017
MARCORA, MARÍA S.; BELFIORI-CARRASCO, LAUTARO F.; BOCAI, NADIA I.; MORELLI, LAURA; CASTAÑO EDUARDO
Amyloid-β42 clearance and neuroprotection mediated by X-box binding protein 1 signaling decline with aging in the Drosophila brain
NEUROBIOLOGY OF AGING; Año: 2017 vol. 60 p. 57 - 70
MORELLI LAURA
La contribución de la hipótesis amiloide a la comprensión de la enfermedad de Alzheimer: una visión crítica
QUíMICA VIVA; Lugar: Buenos Aires; Año: 2016
MARTINEZ-VIVOT, R.; COPELLO, G; LEAL M.C; PIÑEIRO, G; USACH, V; ROZENSZAJN,M; MORELLI L; SETTON-AVRUJ, PC
DMT1 iron uptake in the PNS: bridging the gap between injury and regeneration
METALLOMICS; Lugar: CAMBRIDGE; Año: 2015
MARTINO ADAMI P; QUIJANO C; MAGNANI, N; GALEANO, P.; EVELSON, P; CASSINA A; DO CARMO, S; LEAL M.C; CASTAÑO E.M; CUELLO C; MORELLI L
Synaptosomal bioenergetic defects are associated with cognitive impairment in a transgenic rat model of early Alzheimer?s disease
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM; Lugar: Londres; Año: 2015
MUCHNIK C; OLIVAR N; DALMASSO C; AZURMENDI, P; LIBERCZUK C; MORELLI L; BRUSCO LI
Identification of PSEN2 mutation p.N141I in Argentine pedigrees with early-onset familial Alzheimer's Disease
NEUROBIOLOGY OF AGING; Lugar: Amsterdam; Año: 2015
MARCORA, MS; FERNANDEZ-GAMBA A; AVENDAñO; LA; ROTONDARO, MC; PODHAJCER, O; VIDAL, R; MORELLI L; CERINAI, MF; CASTAñO, EM
Amyloid peptides ABri and ADan show differential neurotoxicity in transgenic
MOLECULAR NEURODEGENERATION; Lugar: Londres; Año: 2014 p. 2 - 14
GALEANO, P.; MARTINO ADAMI P; DO CARMO, S; BLANCO, E.; ROTONDARO C; CAPANI, F.; CASTAñO E.M; CUELLO C; MORELLI L
Longitudinal analysis of the behavioral phenotype in a novel transgenic rat model of early stages of Alzheimer?s disease
Frontiers in Behavioral Neuroscience; Lugar: Lausana; Año: 2014
DE TULIO M; CASTELLETO V; HAMLEY I; MARTINO ADAMI P; MORELLI L; CASTAñO E.M
Proteolytically inactive insulin-degrading enzyme inhibits amyloid formation yielding non-neurotoxic AƒÒ peptide aggregates
PLOS ONE; Lugar: San Francisco; Año: 2013 p. 1 - 13
LEAL M.C; MAGNANI, N; VILLORDO S; MARINO BUSLJE MC; EVELSON, P; CASTAñO E.M; MORELLI L
Transcriptional regulation of Insulin Degrading Enzyme modulates mitochondrial Aâ catabolism and functionality.
JOURNAL OF BIOLOGICAL CHEMISTRY (ONLINE); Año: 2013 p. 1 - 11
MATHIEU, P; MARTINO ADAMI P; MORELLI L
Notch signaling in the pathologic adult brain
BIOMOLECULAR CONCEPTS; Año: 2013 p. 1 - 12
MORELLI L; PERRY, G.; TAGLIAVINI, F
The Contribution of the Amyloid Hypothesis to the Understanding of Alzheimer?s Disease: A Critical Overview
International Journal of Alzheimer`s Disease; Año: 2012 p. 1 - 2
FERNANDEZ-GAMBA AGATA; LEAL MARIA C.; MAAROUF CH; RICHTER-LANDSBERG C; WU T; MORELLI L; ROHER A.E; CASTAÑO E.M
Collapsin response mediator protein-2 phosphorylation promotes the reversible retraction of oligodendrocyte processes in response to non-lethal oxidative stress
JOURNAL OF NEUROCHEMISTRY; Año: 2012 p. 1 - 10
LEAL MC; SURACE EI; HOLGADO MP; FERRARI CC; TARELLI R; PITOSSI F; WISNIEWSKI T; CASTAÑO EM; MORELLI L
Notch signaling proteins HES-1 and Hey-1 bind to insulin degrading enzyme (IDE) proximal promoter and repress its transcription and activity: implications for cellular Abeta metabolism
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH; Año: 2011 p. 227 - 235
BULLOJ, A; LEAL, MC; XU, H; CASTAÑO EM; MORELLI L
Insulin-degrading enzyme sorting in exosomes: a secretory pathway for a key brain Aâ-degrading protease
JOURNAL OF ALZHEIMERS DISEASE; Año: 2010 vol. 19 p. 79 - 95
DANTUR, K; ALONSO L; CASTAÑO EM; MORELLI, L.; CENTENO-CROWLEY, JM; VIGHY, S; DE PRAT GAY, G.
Cytosolic accumulation of HPV16 E7 oligomers supports different transformation routes for the prototypic viral oncoprotein: The amyloid–cancer connection
INTERNATIONAL JOURNAL OF CANCER. JOURNAL INTERNATIONAL DU CANCER.; Año: 2009 vol. 125 p. 1902 - 1911
LEAL MARIA; FERNANDEZ-GAMBA AGATA; MORELLI LAURA; CASTAÑO EDUARDO
Cerebral proteolysis of amyloid-ß peptide: relevance of insulin-degrading enzyme in Alzheimer¡¦s diseas
MEDICINA (BUENOS AIRES); Año: 2009 vol. 69 p. 466 - 472
FERNANDEZ-GAMBA AGATA; LEAL MARIA; MORELLI LAURA; CASTAÑO EDUARDO
Insulin-degrading enzyme: structure-function relationship and its possible roles in health and disease.
CURRENT PHARMACEUTICAL DESIGN.; Año: 2009 vol. 15 p. 3644 - 3655
DE TULLIO MATIAS; MORELLI LAURA; CASTAÑO EDUARDO
The irreversible binding of amyloid peptide substrates to insulin-degrading enzyme. A biological perspective
PRION; Año: 2008 vol. 2 p. 51 - 56
LLOVERA RAMIRO; DE TULLIO MATIAS; ALONSO LEONARDO; LEISSRING MALCOM; KAUFMAN SERGIO; ROHER ALEX; DE PRAT GAY GONZALO; MORELLI LAURA; CASTAÑO EDUARDO
The catalytic domain of insulin-degrading enzyme forms a denaturant-resistant complex with amyloid beta peptide: implications for Alzheimer disease pathogenesis.
JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2008 vol. 283 p. 17039 - 17048
DORFMAN VERONICA; PASQUINI LAURA; RUIDAVETS MIGUEL; LOPEZ-COSTA JUAN; VILLEGAS ANDRES; TRONCOSO JUAN; LOPERA FRANCISCO; CASTAÑO EDUARDO; MORELLI LAURA
Differential deposition of IDE and NEP in sporadic and familial Alzheimer`s disease brain.
NEUROBIOLOGY OF AGING; Año: 2008 p. 9 - 16
BULLOJ AYELEN; LEAL MARIA; SURACE EZEQUIEL; ZHANG XUE; XU HUAXI; LEDESMA MARIA; CASTAÑO EDUARDO; MORELLI LAURA
Detergent resistant membrane-associated IDE in brain tissue and cultured cells: Relevance to Aâ and insulin degradation.
MOLECULAR NEURODEGENERATION; Año: 2008 vol. 3 p. 1 - 13
LEAL MC; DORFMAN VB; FERNANDEZ-GAMBA A; FRANGIONE B; WISNIEUSKI T; CASTAÑO EM; SIGURDDSON E; MORELLI L
Plaque-associated overexpression of Insulin degrading enzyme in the cerebral cortex of aged transgenic Tg2576 mice with Alzheimer pathology. Leal MC
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY; Año: 2006 vol. 65 p. 976 - 987
MORELLI, L.; LLOVERA, RE; ALONSO, L; FRANGIONE, B; DE PRAT GAY, G.; CASTAÑO, EM
Insulin-degrading enzyme degrades amyloid peptides associated with British and Danish familial dementia.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 2005 vol. 332 p. 808 - 816
WEBBER, KM; RAINA, AK.; MARLATT, MW.; ZHU, X.; PRAT, MI.; MORELLI, L.; CASADESUS, G.; PERRY, G.; SMITH, M.
The cell cycle in Alzheimer disease: A unique target for neuropharmacology.
MECHANISMS OF AGEING AND DEVELOPMENT; Año: 2005 vol. 126 p. 1019 - 1025
ZHU, X.; MCSHEA, A.; HARRIS, P.; RAINA, AK.; CASTELLANI, RJ; FUNK, JO.; SHAH, S.; ATWOOD, C.; BOWEN, R.; MORELLI, L; PERRY, G.; SMITH, M
Elevated Expression of a Regulator of the G2/M Phase of the Cell Cycle, neuronal CIP-1 associated regulator of cyclin B, in Alzheimer Disease
JOURNAL OF NEUROSCIENCE RESEARCH; Año: 2004 vol. 75 p. 698 - 703
MORELLI, L.; LOVERA, RE; MATHOV, I.; LUE, L.; FRANGIONE, B; GHISO, J.; CASTAÑO, EM
Insulin-degrading Enzyme in Brain Microvessels Proteolyisis of amyloid ß vasculotropic vatiants and reduced activity in cerebral amyloid angiopathy.
JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2004 vol. 279 p. 56004 - 65013
MORELLI, L.; CASTAÑO, EM
Buscando Blancos terapéuticos para las enfermedades neurodegenerativas: Pin 1 y Tau en la mira
Ciencia Hoy; Año: 2004 vol. 14 p. 30 - 33
MORELLI LAURA; LLOVERA RAMIRO; MATHOV, I; LUE, L.; FRANGIONE B; GHISO, J; CASTAÑO EDUARDO
Insulin-degrading Enzyme in Brain Microvessels Proteolyisis of amyloid ß vasculotropic vatiants and reduced activity in cerebral amyloid angiopathy
JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2004 vol. 279 p. 56004 - 56013
MORELLI LAURA; LLOVERA RAMIRO; GONZALEZ, S; AFRFFRANCHINO, JL; PRELLI, F; FRANGIONE, B; GHISO, J; CASTAÑO EDUARDO
Differential degradation of amyloid beta genetic variants associated with hereditary dementia or stroke by insulin-degrading enzyme.
JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2003 vol. 278 p. 23221 - 23226
PEREZ, A; MORELLI LAURA; CRESTO, JC; CASTAÑO, E.M.
Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains.
NEUROCHEMICAL RESEARCH; Lugar: New York; Año: 2000 vol. 25 p. 247 - 255
LOPEZ SALON; M.; MORELLI L; CASTAÑO E.M; SOTO, E.; PASQUINI, J.M.
Defective Ubiquitination of cerebral proteins in Alzheimer´s disease
JOURNAL OF NEUROSCIENCE RESEARCH; Lugar: New York; Año: 2000 p. 302 - 310
MORELLI L; PRAT, MI.; CASTAÑO E.M
Differential accumulation of soluble amyloid ß peptides 1-40 and 1-42 in human monocytic and neuroblastoma cell lines: implication for cerebral amyloidogenesis
CELL AND TISSUE RESEARCH; Lugar: Berlin; Año: 1999 p. 225 - 232
MORELLI L; GIANBARTOLOMEI GH; PRAT, MI.; CASTAÑO E.M
Internalization and resistance to degradation of Alzheimer¡¦s AƒÒ1-42 at nanomolar concentration in THP-1 human monocytic cell line
NEUROSCIENCE LETTERS; Lugar: Amsterdam; Año: 1998 p. 5 - 8
SOTO, C; SIGURDSSON, E; MORELLI LAURA; KUMAR, R; CASTAÑO E.M; FRANGIONE B
-sheet breaker peptides inhibit fibrillogenesis in rat brain model of amiloidosis: implication for Alzheimer´s therapy
NATURE MEDICINE.; Lugar: Londres; Año: 1998 p. 822 - 826
MORELLI L; PRAT, MI.; LEVY E; MANGONE CA; CASTAÑO EM
Presenilin 1 Met146Leu variant due to an A„_T transition in an Early-Onset Familial Alzheimer¡¦s disease pedigree from Argent
CLINICAL GENETICS; Lugar: Londres; Año: 1997 p. 469 - 473
CASTAÑO EM; PRELLI, F; MORELLI L; AVAGNINA A; KAHAN A; CASTAÑO E.M
Immunoglobulin lambda light chains are the precursors of ureteral localized amyloidoses: a micromethod for extraction of amyloid
AMYLOID; Lugar: London; Año: 1997 p. 253 - 258
MORELLI L; MANGONE CA; LAMBIERTO A; LEONI J; CASTAÑO E.M
Apolipoprotein E polymorphism and late-onset Alzheimer’s disease in Argentina
JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY; Lugar: Londres; Año: 1996 p. 426 - 427
MORELLI L; WEI L; AMORIN A; MCDERMID J; ABEE C; FRANGINE, B; WALKER L; LEVY E
Cerebrovascular amyloidosis in squirrel monkeys and reshus monkeys- Apolopoprotein E genotype
FEBS LETTERS; Lugar: Amsterdam; Año: 1995 p. 132 - 134
WISNIEUSKI T; MORELLI L; WEGIEL J; LEVY E; WISNIEUSKI H; FRANGINE, B
The influence of Apolipoprotein E isotypes on Alzheimer’s Disease Pathology in 40 cases of Down’s Syndrome
ANNALS OF NEUROLOGY; Lugar: New York; Año: 1995 p. 136 - 137
SQUIQUERA L; GALIMBERTI L; MORELLI L; MILICICH L; PLOTKIN L; KOWALKZUK A; LEONI J
Sera of psoriatic patients react with a 120 KD periplasmic protein from Pityrosporum ovale
CLINICAL AND EXPERIMENTAL DERMATOLOGY; Lugar: Londres; Año: 1994 p. 289 - 293
MORELLI L; PLOTKIN L; LEONI J; FOSSATI CA
Analysis of terminal oligossacharides involved in the asymmetrical glycosilation of IgG monoclonal antibodies
MOLECULAR IMMUNOLOGY; Lugar: Amsterdam; Año: 1992 p. 695 - 700
MORELLI L; LEONI J; FOSSATI CA; MARGNI RA
Symmetric and asymmetric IgG1 antibodies are synthezised by the same cellular clone
MOLECULAR IMMUNOLOGY; Lugar: Amsterdam; Año: 1989 p. 789 - 792