INVESTIGADORES
PIROLA Carlos Jose
artículos
Título:
PNPLA3 I148M variant is associated with metabolic stress-response phenotype in patients with nonalcoholic fatty liver disease
Autor/es:
SILVIA SOOKOIAN; GUSTAVO O CASTAÑO; CARLOS JOSE PIROLA
Revista:
HEPATOLOGY (BALTIMORE, MD.)
Editorial:
JOHN WILEY & SONS INC
Referencias:
Lugar: New York; Año: 2015 vol. 61 p. 1769 - 1769
ISSN:
0270-9139
Resumen:
In this case series, we report a novel observation in patients with nonalcoholic fatty liver disease and show a significant association between the PNPLA3 rs738409 (I148M) variant and the lactate-to-pyruvate ratio, confirming the complex liver metabolic regulatory pathway in which PNPLA3 is involved.