INVESTIGADORES
PIROLA Carlos Jose
artículos
Título:
Computational Pipeline for Next-Generation Sequencing (NGS) Studies in Genetics of NASH
Autor/es:
SALATINO, ADRIAN; SOOKOIAN, SILVIA; PIROLA, CARLOS J.
Revista:
METHODS IN MOLECULAR BIOLOGY (CLIFTON, N.J.)
Editorial:
Humana
Referencias:
Lugar: New York, NY; Año: 2022 vol. 2455 p. 203 - 222
ISSN:
1064-3745
Resumen:
High-throughput sequencing (HTS) technologies have contributed to expanding current knowledge of the biology of complex diseases, including nonalcoholic fatty liver disease (NAFLD). Genome-wide association studies, whole-exome sequencing, and sequencing of entire genes are used to identify variants and/or mutations that predispose to the disease pathogenesis. Here, we present a tutorial that may guide readers to manage the high volume of genetics data in the context of Next-Generation Sequencing (NGS) studies.
